November 15th, 2019 by Rukmani Sridharan
Continuous monitoring of bacterial growth is a critical step in the biotechnology industry and in biological labs. These measurements are typically taken using large and bulky spectrophotometers that do not fit into incubators for real-time monitoring. Moreover, continuous monitoring is labor-intensive as it requires multiple samplings. Recent developments by researchers from Cork, Ireland have overcome these challenges by hacking a generic heart rate monitor to make a low-cost turbidity tracker. The team 3D printed a holder where an LED light can shine through, while the sensors' photodiode can measure the...Read More
A good deal of clinical diagnostics are effectively performed by cytologists who examine cells through a microscope for signs of disease. This is an imperfect, slow process that depends on the training, focus, and attention to detail of the cytologist. Now, researchers at Helmholtz Zentrum München and the University Hospital of LMU Munich in Germany have developed an automated system that points to the reality of cytologists becoming an endangered species. They taught a computer, running deep learning algorithms, to automatically classify cells within blood samples for signatures of acute...Read More

November 14th, 2019 by Medgadget Editors
Electrospinning is a maturing manufacturing technology that is already being used in medicine to produce unusual materials with novel properties. It involves melting a polymer and extruding it through a narrow nozzle, while an electric field is used to pull and spin the polymer into a very fine mesh. When a biocompatible polymer is used, the printed materials may be applicable for medical applications, as the resulting mesh has an extremely large surface area. The fibers can also have drugs attached to them, resulting in active meshes with interesting therapeutic...Read More
Butterfly Network, the digital health unicorn democratizing medical imaging, is continuing to add new applications for its handheld, single probe, smartphone-connected ultrasound technology. The Butterfly iQ, the multi-purpose pocket-sized ultrasound, won FDA clearance a couple years ago and earlier this year received the CE Mark, clearing it for distribution in Europe. The innovation found within Butterfly iQ centers around the device's matrix array of microelectromechanical (MEMS) sensors. As part of an integrated circuit, Butterfly iQ provides high-resolution performance comparable to that of a full-size ultrasound machine. Similar to the ubiquity...Read More
Scientists at Harvard’s Wyss Institute have developed a technique to deliver chemotherapy to the lungs using red blood cells. The method involves binding chemotherapy-loaded nanoparticles to red blood cells, which are then injected into the bloodstream. Once the red blood cells reach the lungs they have to squeeze through the small capillaries and the resulting shear force removes the nanoparticles, which can then enter cells within the lungs. The researchers hope that the technique could help treat lung metastases with increased efficacy and reduced side-effects, compared with conventional chemotherapy.  ...Read More

November 14th, 2019 by Medgadget Editors
Drug-releasing implants may have significant benefits for treating a variety of diseases. They're already used in a few limited applications, but wider implementation has proven to be challenging because it is difficult to know how a drug moves through the implant and into the surrounding tissues. Now, researchers at Purdue University have developed a way to use an MRI machine to view the movement of a drug through and out of a drug eluting implant. The capability will allow drug implant developers to study how their designs work with different...Read More
Surgeons at the Cleveland Clinic managed to implant a donor kidney into a patient using a surgical robot, and all through one small incision. The technique, in which instruments as well as the donor kidney can be passed through a four centimeter (1.6 inch) wide incision, is designed to make it easier to perform transplants on patients with difficult anatomies and to cause less collateral damage to internal and external tissues. “The aim was not only to make a smaller incision, but also to minimize the area in which the...Read More
Eyevensys, a clinical-stage biotechnology company based in France, has developed a method to perform non-viral gene therapy in the eye, with the aim of treating ocular diseases. The system uses ocular electrotransfection to deliver therapeutic genes into the eye. Consisting of an ocular device and an electrical pulse generator, the system can deliver DNA plasmids into the ciliary muscle. The idea is that the transfected cells in the eye allow for sustained local production of therapeutic proteins, which can then produce effects in a variety of structures in the eye,...Read More
Nevro, a firm based in Silicon Valley, won FDA approval for its Senza Omnia spinal cord neurostimulation system for chronic pain management. The device can deliver traditional spinal cord stimulation at frequencies below 1.5 kHz, along with Nevro's proprietary HF10 stimulation that goes up to 10 kHz. Both low and high frequency therapies can even be provided at the same time. The Senza Omnia can operate at frequencies between 2 and 10,000 Hertz, a range unheard of in a spinal cord stimulator. It is a rechargeable device and is guaranteed...Read More
Transcutaneous electrical muscle stimulation is used in a variety of clinical applications, including as a rehabilitation tool to help people with limited mobility. It is effective for maladies such as certain types of urinary incontinence, for example, but getting the muscles of the arm to move in unison and with appropriate strength via electrical stimulation through the skin is very difficult. Researchers at The Feinstein Institutes for Medical Research, a part of Northwell Health, a New York State healthcare network, have now developed a system that can, without relying on...Read More

November 12th, 2019 by Conn Hastings
Researchers at the University of Wisconsin-Madison have developed an injectable flexible electrode that can aid in neuromodulation therapy, potentially replacing more rigid electrodes that do not mesh well with soft tissues. The injectable material consists of a silicone gel and small metal particles, and it forms a flexible bolus when injected around a target nerve. The nerve can then be electrically stimulated from the surface of the skin using a basic transcutaneous electrical nerve stimulation (TENS) unit. The approach could pave the way for effective neuromodulation therapy for a large...Read More

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Injectable Electrodes for Neuromodulation

Researchers at the University of Wisconsin-Madison have developed an injectable flexible electrode that can aid in neuromodulation therapy, potentially replacing... November 12th, 2019


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