Japan Epigenetics Market is estimated to witness a rise in revenue from US$ 23.6 Mn in 2021 to US$ 48.6 Mn by 2027. The market is growing at a CAGR of 12.8% during the forecast period from 2022 to 2027.
The Japan epigenetics market is experiencing a remarkable surge, propelled by various factors. One primary driver is the escalating prevalence of chronic diseases, necessitating extensive medical scrutiny. Coupled with advancements in treatment technologies, this has fueled the growth trajectory of the market. Additionally, the aging population in Japan has contributed to the surge in demand for research and development activities in the field of epigenetics. Moreover, the government’s favorable support for epigenetic procedures has further bolstered the market’s expansion. Excitingly, the integration of cutting-edge technologies such as artificial intelligence and machine learning into the realm of epigenetics has unlocked tremendous growth opportunities for the market.
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The Japan epigenetics market is being driven by a significant increase in pharmaceutical research and development (R&D) investments and expenditures This indicates a growing focus on exploring the potential of epigenetics in drug discovery and development. Additionally, healthcare providers are under mounting pressure to lower healthcare expenses, which has led to a greater emphasis on finding innovative and cost-effective solutions, such as epigenetic therapies.
Researchers have discovered that differences in the epigenetic states between healthy and diseased tissues can serve as valuable biomarkers for diseases This has opened up new possibilities for diagnosing and treating various conditions. Epigenetics has already made a significant impact on drug discovery, with several drugs and therapies targeting epigenetic modifications now available. Although the number of approved drugs in this category is currently limited, researchers are actively exploring innovative approaches, such as protein degraders (PROTACs) and antibody-drug conjugates, to enhance the effectiveness and reduce the side effects of epigenetic inhibitors.
Epigenetics in Cancer Treatment: Offering Immense Opportunity for Prominent Players
The demand for epigenetics is growing because of its growing use in cancer treatment. According to data from the National Center for Biotechnology Information (NCBI), the prevalence of cancer in Japan is projected to increase by 13.1% by 2050, with an estimated 3,665,900 thousand cases. Among males, prostate, lung, and malignant lymphoma cancers are expected to see the highest absolute increases in prevalence, while among females, female breast, colorectal, and corpus uteri cancers are projected to have the highest absolute increases.
Epigenetic dysregulation is frequently associated with human diseases, particularly cancer. The use of targeted epigenetic mechanisms in the treatment of hematological abnormalities has shown promising therapeutic potential, and various medications targeting epigenetic regulators have emerged. The chief of the Carcinogenesis Division at Japan’s National Cancer Center Research Institute has emphasized the significance of epigenetic mechanisms in the field of cancer, accounting for a substantial portion of known genetic alterations.
Epigenetic therapy has demonstrated its efficacy in treating various types of cancer. As the understanding and utilization of these mechanisms in cancer treatment continue to advance, the epigenetics market in Japan is experiencing significant growth.
A breakthrough in this field has been achieved by an international team of researchers. They conducted a comprehensive analysis of 1.7 million cells from 225 samples, including primary and metastatic cancer cells from 205 patients with 11 different cancer types. The team obtained the complete transcriptome, exome, and epigenome data for each cell, covering gene mutations, gene accessibility, and their consequences. Through powerful computational analysis, they were able to deduce the functional status of each analyzed cell, linking it to its specific cancer type. This milestone represents a significant advancement in our understanding of cancer and its epigenetic components.
Adoption of Advanced Technology: A Promising Future for the Market
The field of epigenetics is undergoing a remarkable transformation with the integration of artificial intelligence (AI) and machine learning (ML) techniques. This fusion of cutting-edge technology has the potential to revolutionize epigenetics research, offering a deeper understanding of gene regulation and disease mechanisms.
AI algorithms, including machine learning and deep learning, are being harnessed to develop powerful epigenetic classifiers for a wide range of applications. One notable example is the development of machine learning-based epigenetic classifiers for axillary staging of breast cancer. These classifiers leverage the immense power of AI to analyze complex epigenetic data, providing accurate predictions about the spread of cancer to the lymph nodes. This breakthrough has the potential to greatly assist medical professionals in determining appropriate treatment plans.
The impact of AI and machine learning in the field of epigenetics extends far beyond research applications. These technologies have also been utilized to aid in diagnostic cytology and genomic analysis. By leveraging the capabilities of AI, medical experts can effectively interpret intricate cytological and genomic data, leading to more precise diagnoses and personalized treatment strategies. This integration of AI and machine learning into diagnostic processes has the potential to revolutionize the way diseases are detected and treated.
The adoption of AI and machine learning in epigenetics has paved the way for remarkable progress in research, diagnostics, and even drug development. These technologies hold the key to unlocking new insights into the complex realm of gene regulation and disease mechanisms, ultimately leading to improved healthcare outcomes. As a result, the market for AI and machine learning in epigenetics is expected to experience significant growth, as their potential impact becomes increasingly recognized and embraced by the scientific and medical communities.
Key Takeaways for Epigenetics Market
- Based on product type, the kits segment accounted for the highest share in the Japan epigenetics market in 2021 and is likely to grow at the highest CAGR during the forecast period due to the increased usage of kits in epigenetics mechanisms.
- In terms of technology, the DNA methylation segment will generate maximum revenue share over the forecast period due to the high application of this technique in research and academic institutes. On the other hand, the bromodomains segment is likely to hold the highest CAGR from 2022 to 2027.
- By application, the oncology segment generated the highest revenue share in Japan epigenetics market in 2021 and will register the highest CAGR during the analysis period due to the growing applications of epigenetics in cancer treatment. The ongoing research in the oncology field to stimulate the treatment process is further anticipated to propel segmental growth in the near future.
- Based on end-users, the pharmaceutical & biotechnology companies dominated the Japan epigenetics market in 2021 owing to R&D for drug resistance developed by microorganisms, oncology, molecular aspects of cancer, and drug discovery for non-oncology applications. On the other hand, the academic and research institutes segment is expected to project the highest CAGR during the forecast period.
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Top Companies in the Japan Epigenetics Market
- Abcam PLC
- Daiichi Sankyo Company Limited
- Illumina, Inc.
- Rhelixa Inc.
- National Institute of Genetics
- Takeda Pharmaceutical Company Limited
- Other Prominent Players
By Product Type
- Bisulfite Conversion Kits
- ChIP Kits
- RNA Kit
- Software Tools
- BiQ Analyzer
- Proteins & Peptides
- DNA Methylation
- Histone Methylation
- Histone Acetylation
- Non-coding RNA
- Cardiovascular diseases
- Academic and Research Institutes
- Pharmaceutical & Biotechnology Companies
- Contract Research Organizations (CROs)
- Research and consulting firms
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