(Albany, USA) DelveInsight’s ‘Hepatocellular Carcinoma Pipeline Insight 2023‘ report provides comprehensive global coverage of pipeline Hepatocellular Carcinoma therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the Hepatocellular Carcinoma pipeline domain.
For Hepatocellular Carcinoma emerging drugs, the Hepatocellular Carcinoma pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.
Key Takeaways from the Hepatocellular Carcinoma Pipeline Report
- DelveInsight’s Hepatocellular Carcinoma Pipeline analysis depicts a robust space with 90+ active players working to develop 95+ pipeline therapies for Hepatocellular Carcinoma treatment.
- The leading Hepatocellular Carcinoma companies include Can-Fite BioPharma, Sinocelltech, AVEO Oncology, Oxford BioTherapeutics, Beijing SyngenTech, Surface Oncology, Novartis Oncology, Array BioPharma, Taizhou Hanzhong Pharmaceuticals, Akeso Biopharma, Shanghai Henlius Biotech, Chugai Pharmaceutical, CStone Pharmaceuticals, Shenogen Pharma, GlaxoSmithKline, Tarus Therapeutics, Tvardi Therapeutics, Virogin Biotech, Yiviva, Chia Tai Tianqing Pharmaceutical Group, Antengene Corporation, Iterion Therapeutics, Sumitomo Pharma, SillaJen Biotherapeutics, SCG Cell Therapy, Guangdong ProCapZoom Biosciences, Eutilex, Polaris Pharmaceuticals, OriCell Therapeutics, Gongwin Biopharm, Celgene Corporation, Phanes Therapeutics, MacroGenics, Genoscience Pharma, Tempest Therapeutics, JW Therapeutics, NETRIS Pharma, Adagene, and others are evaluating their lead assets to improve the Hepatocellular Carcinoma treatment landscape.
- Key Hepatocellular Carcinoma pipeline therapies in various stages of development include Namodenoson, Tivozanib, SCT-I10A, OBT-624, SynOV1.1, SRF388, INC280, HX008, AK104, Serplulimab, ERY974, Fisogatinib, Icaritin, TSR-022, TT-4, TTI-101, VG161, YIV-906, TQB2450, ATG 008, BBI608, Tegavivint, Pexastimogene Devacirepvec, SCG101, SZ003, EU307, ADI-PEG20, Ori-C101, Para-Toluenesulfonamide, CC-122, PT199, vobramitamab duocarmazine, ezurpimtrostat, TPST-1120, JWATM214, NP137, ADG126, and others.
- In July 2023, the FDA accepted for evaluation a new drug application seeking approval of rivoceranib in conjunction with camrelizumab as a first-line therapy option for patients with unresectable hepatocellular carcinoma (HCC).
- In July 2023, Can-Fite BioPharma Ltd., a biotechnology company developing a pipeline of proprietary small molecule drugs to treat oncology, inflammatory, and liver diseases, announced that its abstract titled “A novel approach for the treatment of advanced hepatocellular carcinoma (HCC)” was one of the highest scoring abstracts and received the prestigious Breakthrough Abstract Award from Conquer Cancer, the ASCO Foundation, and the 2023 ASCO Breakthrough Programme Committee.
- In May 2023, Harbour BioMed announced the results of the phase Ib clinical trial of porustobart (HBM4003), in combination of toripalimab in patients with hepatocellular carcinoma (HCC) (trial code: NCT05149027) were released at the American Society of Clinical Oncology (ASCO) Annual Meeting 2023.
- In April 2023, Tempest Therapeutics announced positive early results from a global randomized Phase Ib/II clinical study in which TPST-1120, Tempest’s small molecule PPAR⍺ antagonist, demonstrated clinically-meaningful improvement in multiple categories when combined with the standard-of-care regimen of atezolizumab and bevacizumab in a randomized comparison to atezolizumab and bevacizumab in the first-line treatment of patients with unresectable or metastatic hepatocellular carcinoma (HCC).
Request a sample and discover the recent breakthroughs happening in the Hepatocellular Carcinoma pipeline landscape @ Hepatocellular Carcinoma Pipeline Outlook
Hepatocellular Carcinoma Overview
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, accounting for the majority of cases. It typically originates in hepatocytes, the main type of liver cells. HCC can have serious consequences, as it tends to progress rapidly and may spread to other parts of the body if not detected and treated early. Several factors can contribute to the development of hepatocellular carcinoma. Chronic viral infections, particularly hepatitis B and C, are considered major risk factors.
The symptoms of hepatocellular carcinoma can vary depending on the stage of the disease. In the early stages, individuals may experience no symptoms at all. As cancer progresses, common symptoms may include abdominal pain or discomfort, weight loss, loss of appetite, fatigue, jaundice (yellowing of the skin and eyes), abdominal swelling, and easy bruising or bleeding.
Diagnosing hepatocellular carcinoma typically involves a combination of imaging tests, blood tests, and a biopsy. Imaging tests such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) can help visualize the liver and detect any suspicious masses. Blood tests may be done to assess liver function and check for specific markers that indicate HCC. If a suspicious mass is found, a biopsy may be performed to obtain a sample of the liver tissue for further analysis and confirmation of the diagnosis.
Find out more about Hepatocellular Carcinoma medication @ New Drug for Hepatocellular Carcinoma
Hepatocellular Carcinoma Treatment Analysis: Drug Profile
Namodenoson: Can-Fite BioPharma
Namodenoson, also known as Cl-IB-MECA (2-chloro-N6-(3-iodobenzyl)-adenosine-5′- N-methyl-propanamide), is an oral small molecule medication that is a highly specific and selective agonist at the A3 adenosine receptor (A3AR). For treating liver cancer and NASH, the medication was out-licensed to Chong Kun Dang (CKD) Pharmaceutical in Korea and CMS in China. Phase I/II research in hepatocellular carcinoma (HCC) satisfied its primary and secondary goals, indicating early indications of Namodenoson efficacy. A global Phase II research using Namodenoson as a second-line treatment on patients was just completed. Although the primary aim of overall survival was not met, a significant clinical impact was seen in a subset of Child-Pugh B7 (CPB7) patients. The Company secured an agreement with the FDA and the EMA on a Phase III protocol in the CPB7 population during an End-of-Phase II conference. The medication is now in Phase III development for the treatment of Hepatocellular carcinoma.
SRF388: Surface Oncology
SRF388 is a fully human anti-IL-27 antibody that is intended to block the function of this immunosuppressive cytokine. IL-27 is an immunosuppressive cytokine that has a role in the resolution of T cell-mediated inflammation. Recent evidence suggests that IL-27 is a master regulator of the production of co-inhibitory receptors on CD4+ and CD8+ T cells. Cancer has elevated amounts of IL-27 transcripts and mRNA gene signatures, which are associated with a bad prognosis. Surface Oncology has discovered several tumor forms in which IL-27 appears to play a major function in the immunosuppressive tumor microenvironment and may lead to checkpoint inhibitor resistance. Surface Oncology has also identified a possible biomarker related to IL-27 that may be beneficial in identifying individuals who are most likely to respond to SRF388. The drug is currently in Phase II development for the treatment of Hepatocellular carcinoma.
Key Hepatocellular Carcinoma Therapies and Companies
- Namodenoson: Can-Fite BioPharma
- SCT-I10A: Sinocelltech
- SRF388: Surface Oncology
- Capmatinib: Novartis Oncology
- Fisogatinib: CStone Pharmaceuticals
- Tivozanib: AVEO Oncology
- ERY974: Chugai Pharmaceutical
Learn more about the novel and emerging Hepatocellular Carcinoma pipeline therapies @ Hepatocellular Carcinoma Clinical Trials
Hepatocellular Carcinoma Therapeutics Assessment
- By Product Type
-
- Monotherapy
- Combination Therapy
- By Stage
-
- Discovery
- Pre-Clinical
- Phase I
- Phase II
- Phase III
- Pre-registration
- By Route of Administration
-
- Intra-articular
- Intraocular
- Intrathecal
- Intravenous
- Ophthalmic
- Oral
- Parenteral
- Subcutaneous
- Topical
- Transdermal
- By Molecule Type
- Oligonucleotide
- Peptide
- Small molecule
Scope of the Hepatocellular Carcinoma Pipeline Report
- Coverage: Global
- Key Hepatocellular Carcinoma Companies: Can-Fite BioPharma, Sinocelltech, AVEO Oncology, Oxford BioTherapeutics, Beijing SyngenTech, Surface Oncology, Novartis Oncology, Array BioPharma, Taizhou Hanzhong Pharmaceuticals, Akeso Biopharma, Shanghai Henlius Biotech, Chugai Pharmaceutical, CStone Pharmaceuticals, Shenogen Pharma, GlaxoSmithKline, Tarus Therapeutics, Tvardi Therapeutics, Virogin Biotech, Yiviva, Chia Tai Tianqing Pharmaceutical Group, Antengene Corporation, Iterion Therapeutics, Sumitomo Pharma, SillaJen Biotherapeutics, SCG Cell Therapy, Guangdong ProCapZoom Biosciences, Eutilex, Polaris Pharmaceuticals, OriCell Therapeutics, Gongwin Biopharm, Celgene Corporation, Phanes Therapeutics, MacroGenics, Genoscience Pharma, Tempest Therapeutics, JW Therapeutics, NETRIS Pharma, Adagene, and others.
- Key Hepatocellular Carcinoma Pipeline Therapies: Namodenoson, Tivozanib, SCT-I10A, OBT-624, SynOV1.1, SRF388, INC280, HX008, AK104, Serplulimab, ERY974, Fisogatinib, Icaritin, TSR-022, TT-4, TTI-101, VG161, YIV-906, TQB2450, ATG 008, BBI608, Tegavivint, Pexastimogene Devacirepvec, SCG101, SZ003, EU307, ADI-PEG20, Ori-C101, Para-Toluenesulfonamide, CC-122, PT199, vobramitamab duocarmazine, ezurpimtrostat, TPST-1120, JWATM214, NP137, ADG126, and others.
Dive deep into rich insights for drugs used for Hepatocellular Carcinoma treatment; visit @ Hepatocellular Carcinoma Drugs
Table of Contents
| 1. | Introduction |
| 2. | Executive Summary |
| 3. | Hepatocellular Carcinoma Pipeline: Overview |
| 4. | Analytical Perspective In-depth Commercial Assessment |
| 5. | Hepatocellular Carcinoma Pipeline Therapeutics |
| 6. | Hepatocellular Carcinoma Pipeline: Late Stage Products (Phase III) |
| 7. | Hepatocellular Carcinoma Pipeline: Late Stage Products (Phase III) |
| 8. | Hepatocellular Carcinoma Pipeline: Mid-Stage Products (Phase II) |
| 9. | Hepatocellular Carcinoma Pipeline: Early Stage Products (Phase I) |
| 10. | Therapeutic Assessment |
| 11. | Inactive Products |
| 12. | Company-University Collaborations (Licensing/Partnering) Analysis |
| 13. | Key Companies |
| 14. | Key Products |
| 15. | Unmet Needs |
| 16. | Market Drivers and Barriers |
| 17. | Future Perspectives and Conclusion |
| 18. | Analyst Views |
| 19. | Appendix |
For further information on the Hepatocellular Carcinoma therapy in the pipeline, reach out @ Hepatocellular Carcinoma Medication
Related Reports
Hepatocellular Carcinoma Epidemiology
Hepatocellular Carcinoma Epidemiology Forecast – 2032 report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the hepatocellular carcinoma epidemiology trends.
Hepatocellular Carcinoma Market
Hepatocellular Carcinoma Market Insights, Epidemiology, and Market Forecast – 2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key hepatocellular carcinoma companies, including Surface Oncology, Novartis Oncology, Array BioPharma, Taizhou Hanzhong Pharmaceuticals, Akeso Biopharma, Innovent Biologics, Eli Lilly and Company, Shanghai Henlius Biotech, Chugai Pharmaceutical, CStone Pharmaceuticals, among others.
Metastatic Hepatocellular Carcinoma Market
Metastatic Hepatocellular Carcinoma Market Insight, Epidemiology, and Market Forecast – 2032 report delivers an in-depth understanding of the market trends, market drivers, market barriers, and key metastatic hepatocellular carcinoma companies, including BeiGene, Zai Lab (Shanghai) Co., Geneos Therapeutics, Adaptimmune Therapeutics, among others.
Metastatic Hepatocellular Carcinoma Pipeline
Metastatic Hepatocellular Carcinoma Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key metastatic hepatocellular carcinoma companies, including BeiGene, Zai Lab (Shanghai) Co., Geneos Therapeutics, Adaptimmune Therapeutics, among others.
Advanced Hepatocellular Carcinoma Pipeline
Advanced Hepatocellular Carcinoma Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key advanced hepatocellular carcinoma companies, including CStone Pharmaceuticals, TaiRx, Yiviva, AVEO Oncology, Eureka Therapeutics, Shanghai Henlius Biotech, Innovent Biologics, Akesobio, among others.
Advanced Hepatocellular Carcinoma with CPB Liver Cirrhosis Pipeline
Advanced Hepatocellular Carcinoma with CPB Liver Cirrhosis Pipeline Insight – 2023 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key advanced hepatocellular carcinoma with CPB liver cirrhosis companies, including Can-Fite Biopharma, among others.
Other Trending Reports
T-Cell Prolymphocytic Leukemia Market | Acral Lentiginous Melanoma Market | Malt Lymphoma Market | Primary Progressive Multiple Sclerosis Ppms Market | 3d Cardiac Mapping System Market | Adult Growth Hormone Deficiency Market | Angioedema Market | Pain Management Devices Market | Allergic Rhinoconjunctivitis Market | Multiple Myeloma Market | Blood Gas And Electrolyte Analyzers Market | Helicobacter Pylori Infection Market | Helicobacter Pylori Infections Market | Cardiac Amyloidosis Market | Cardiac Resynchronization Therapy Device Market | Cerebral Aneurysm Market | Anemia In Ckd Market | Capnography Device Market | Cutaneous T-cell Lymphoma Market | Chronic Hepatitis B Virus Market | Ventricular Hypertrophy Market | Parkinson’s Disease Market | Penicillinbinding Proteins Market | Critical Limb Ischemia Market | Hemophilia B Market | Cardiotoxicity Market | Xerostomia Market | Alopecia Market | Asmd Market | Hypothalamic Obesity Market | Chronic Cutaneous Ulcer Market | Chronic Insomnia Market
Related Healthcare Services
Healthcare Competitive Intelligence Services
Healthcare Asset Prioritization Services
About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. Get hassle-free access to all the healthcare and pharma market research reports through our subscription-based platform PharmDelve.
Connect With Us at LinkedIn | Facebook | Twitter
Contact Us
Sandeep Joshi
info@delveinsight.com
+1(919)321-6187