The melatonin API market has experienced significant growth and demand in recent years. Melatonin, a hormone produced naturally by the pineal gland in the brain, plays a crucial role in regulating sleep-wake cycles. Due to its potential benefits in treating sleep disorders and jet lag, the market for melatonin API (active pharmaceutical ingredient) has expanded rapidly, attracting attention from pharmaceutical companies and healthcare professionals worldwide.
The global melatonin API market recorded a CAGR of 14.3% in the last 5 years and reached a valuation of US$ 1.7 billion in 2022. The market is forecasted to expand at a high-value CAGR of 15.1% to surge to US$ 10.1 billion by the end of 2033.
According to this study by Persistence Market Research, GMP grade manufacturing accounted for a market share of 93.5% in 2022. Overall, melatonin API sales accounted for 6.4% revenue share of the global sleep aids market in 2022.
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One key driver behind the growth of the melatonin API market is the rising prevalence of sleep disorders. In today’s fast-paced society, insomnia and other sleep-related conditions have become increasingly common. Melatonin supplements, which can help regulate sleep patterns, have gained popularity as a non-prescription solution for individuals seeking better sleep quality. This increased demand has led to a surge in the production and availability of melatonin API.
- Merck KGaA
- Caesar & Loretz GmbH
- Bio-Techne Corp.
- Cayman Chemical Company (Matreya)
- Spectrum Chemical
- Caesar & Loretz GmbH
- LGM Pharma
- Flavine Europe GmbH
- Ralington Pharma
- SimSon Pharma Limited
- Santa Cruz Biotechnology, Inc.
- Otto Chemie Pvt. Ltd.
- Pharmaffiliates Analytics and Synthetics P. Ltd.
- Clearsynth Labs
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Moreover, the use of melatonin API extends beyond sleep disorders. Research suggests that melatonin may have potential applications in other areas of healthcare, such as treating certain neurological conditions, reducing symptoms of seasonal affective disorder (SAD), and even mitigating the side effects of cancer treatment. These potential therapeutic uses have generated further interest in the melatonin API market, as pharmaceutical companies explore new formulations and drug combinations.
In addition, the growing trend of self-care and wellness has contributed to the expansion of the melatonin API market. Many individuals are actively seeking natural and alternative remedies to improve their overall well-being. Melatonin supplements, with their reputation for promoting healthy sleep, have become a popular choice among consumers looking for non-invasive approaches to managing sleep-related issues. As a result, the market for melatonin API has seen a surge in demand from dietary supplement manufacturers and retailers.
Furthermore, the increasing geriatric population has also played a significant role in the growth of the melatonin API market. Older adults often experience age-related changes in sleep patterns, leading to difficulties falling asleep or staying asleep. Melatonin supplements offer a potential solution for addressing these sleep disturbances in the elderly population. With the global population aging rapidly, the demand for melatonin API is expected to continue rising in the coming years.
However, it’s important to note that the melatonin API market also faces challenges and regulatory considerations. While melatonin is widely regarded as safe for short-term use, the long-term effects and optimal dosages are still being studied. Regulatory bodies around the world have varying guidelines and restrictions regarding the sale and use of melatonin supplements. Compliance with these regulations and ensuring quality control in the production of melatonin API remain critical factors for companies operating in this market.
The growth of the melatonin API industry has been facilitated by low-cost inventions, production, skilled labor, and innovative research and development activities in countries such as India. Additionally, businesses are able to accomplish complex synthesis with efficiency and in a significantly shorter amount of time.
Companies that produce melatonin APIs are concentrating on forming alliances with new businesses to expand their presence in the industry and attract more clients to meet demand. Acquisitions are another important promotional strategy used in this market. Through acquisitions, businesses can improve their capabilities, increase their geographic coverage, and diversify their product portfolio.
Some key market developments include:
- Biosynth Carbosynth, which is financed by KKR, acquired Vivitide in March 2022 and welcomed Ampersand Capital Partners as a new shareholder.
- The launch of Bio-Techne Corporation’s unique GMP facility, which is located in St. Paul, Minnesota, and measures about 61,000 square feet, was implemented in September 2020. The purpose of the new facility is to support the industrial-scale manufacturing of GMP-grade components.
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Key Segments of Melatonin API Industry Research
- North America
- Latin America
- South Asia
- East Asia
- Middle East & Africa
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