Blood irradiators are utilized for the irradiation of blood and its components to impede the growth of T lymphocytes, which can hinder the immune response, causing graft-versus-host disease (GVHD). These irradiators are extensively employed in several medical and research settings, such as blood transfusion preparation and cancer research. The irradiation process is imperative for transfusion recipients susceptible to GVHD, including fetuses receiving intrauterine transfusions, patients undergoing hematopoietic transplantation, and individuals receiving platelets. Blood irradiators have various applications in the irradiation of blood, which is essential for surgeries, cancer treatment, chronic illnesses, and traumatic injuries.
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Blood Irradiator Market Drivers
Blood transfusion can lead to rare but severe complications such as transfusion-associated graft-versus-host disease (TA-GVHD), caused by the white blood cells in the transfused blood attacking the recipient’s body. To prevent this, irradiated blood is provided. According to the Royal Children’s Hospital Melbourne, TA-GVHD occurs when lymphocytes from the transfused blood engraft in the recipient, leading to hepatitis, diarrhea, and pancytopenia, accompanied by clinical symptoms of fever and skin rash. Unfortunately, TA-GVHD is fatal in over 90% of cases.
The market growth of blood irradiators is also driven by government organizations’ support for the development of new irradiators to guarantee safe blood transfusions. For example, the Department of Energy awarded a $1.1 million grant to Stellarray, Inc. in 2014 to develop and market novel irradiators for replacing cesium-137, which is recognized as a national security hazard and ensuring blood transfusion safety.
Additionally, the Advancing Transfusion Cellular Therapies Worldwide (AABB) organization collaborates with the Food and Drug Administration (FDA) to establish proper guidelines and regulations for the irradiation of blood products, promoting the use of blood irradiators by ensuring safety and compliance to restrict the use of radioactive irradiators.
However, the lack of awareness among population regarding uses and benefits of irradiators in the healthcare facilities and high cost of the irradiators are the factors hindering the market growth. For instance, according to the survey by College of American Pathologists, 2017, the cost of X-ray irradiators is around US$ 250,000 to US$ 300,000, with annual service contract accounting for US$ 15,000 to US$ 20,000.
Blood Irradiator Market – Competitive Landscape
The major players operating in the global blood irradiator market are emphasizing on strategic mergers and acquisitions to increase the adoption of blood irradiators worldwide. As an example, Charter Medical has teamed up with RadTag Technologies to distribute RadTag blood irradiator indicators in the United States.
Among the major players in the global market for blood irradiators are Sukosol Group, Typenex Medical, Gamma-Service Medical GmbH, Best Theratronics, Ltd., Cegelec NDT-PES, and Rad Source Technologies.
Blood Irradiator Market – Market Taxonomy
The worldwide blood irradiator market is divided into the following categories based on product type:
- X-ray Irradiators
- Gamma-ray Irradiators
On the basis of end user, the global blood irradiator market is segmented into:
- Hospitals
- Research Institutions
- Blood Banks
The worldwide blood irradiator market is divided into the following regions based on geography:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
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Blood Irradiator Market – Regional Insights
The global market for blood irradiators is segmented into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America currently holds the dominant position in the global blood irradiator market due to the launch and adoption of novel technologies. In September 2017, Typenex Medical launched Rad-Control, a new irradiation indicator tag technology in the blood banks and blood centers in the United States and Canada. This technology ensures that the blood component has received proper irradiation, thereby preventing life-threatening transfusion-associated Graft-vs.-Host Disease (TA-GvHD).
Additionally, the growth of the blood irradiator market is expected to be fueled by the rising adoption of X-ray irradiators. The U.S. Department of Energy’s National Nuclear Security Administration (DOE/NNSA) collaborated with the New York City Department of Health and Mental Hygiene (DOHMH) and the Nuclear Threat Initiative (NTI) in 2017 to replace the hazardous radioactive irradiators with safer X-ray alternatives.
In addition, the growing incidence of diseases in the region that require blood transfusions is a significant factor contributing to the market growth. According to the American National Red Cross, sickle cell disease affects between 90,000 to 100,000 people in the U.S. each year, and about 1,000 babies are born with the disease annually. Patients with sickle cell disease often require blood transfusions throughout their lifetime. Furthermore, according to the American Cancer Society, it is estimated that about 1.7 million people in the U.S. will be diagnosed with cancer in 2023, and many of these patients will require blood transfusions during chemotherapy treatments.
In addition, the North American market is anticipated to witness significant growth due to the widespread use of blood irradiators in medical facilities to prevent and manage the spread of transfusion-associated graft-versus-host disease (TA-GVHD). The Department of Health and Human Services has reported that in 2013, approximately 500 blood irradiators were used to irradiate nearly 2 million blood units, which further supports the potential growth of the market in the region.
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