The research study on the ’U.S. Gene Editing Market – Industry Outlook & Forecast 2022-2027’, recently published by Arizton Advisory & Intelligence, states that the market will grow at a CAGR of 21.13% during 2022-2027.
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Market Overview
The US gene editing market to reach $9.16 billion by 2027. Cell and gene therapies are advanced medicinal products that treat severe and rare diseases, cancer, and other communicable and non-communicable diseases. Increasing research and development in cell & gene therapy has boosted market growth in recent years. Government, as well as industrial and academic financing and collaboration among small and large biopharmaceutical companies, offer significant growth to the market in the coming years.
Gene therapy gathered the pace in the last 2 decades because of the discovery of several genes responsible for mutation in various diseases. The advancement in this field and innovative technologies are creating a new era for biological therapeutics. Also, PRIME Designation and marketing authorization for products provide a new opportunity for the manufacturer’s financing and revenue generation.
The U.S. Gene Editing Market Report Scope
| Report Attributes | Details |
| Market Size (2027) | USD 9.16 Billion |
| Market Size (2021) | USD 2.90 Billion |
| CAGR (2022-2027) | 21.13% |
| Base Year | 2021 |
| Forecast Year | 2022-2027 |
| Market Segments | Products, Technology, Application, and End User |
| Geographic Analysis | United States |
| Market Dynamics |
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Recent Developments and Partnerships
- The most exciting developments in CRISPR therapeutics often come from start-ups. However, CRISPR is also attracting big pharmaceutical companies to start-up companies. Start-ups and big pharma companies frequently partner with companies offering gene editing approaches and technologies in the U.S. gene editing market.
- The latest genome-editing company to partner with a major pharmaceutical company is Beam Therapeutics, which pioneered the fundamental editing of human disease. In January 2022, Beam and Pfizer announced their four-year exclusive research collaboration focused on an in vivo baseline treatment program.
- In January 2022, Bayer and Mammoth Biosciences collaborated on novel gene editing technology. Mammoth Biosciences received USD 40 million to develop an in vivo gene-editing therapy.
- In November 2021, Moderna collaborated with Metagenomi to add CRISPR-based and other novel gene-editing systems to the company’s mRNA/LNP expertise to develop in vivo gene-editing therapeutics.
- In February 2022, a gene-editing company, Intellia Therapeutics, and ONK Therapeutics, a company developing natural killer (NK) cell therapies in oncology, announced a licensing and collaboration agreement. ONK will take a non-exclusive license to Intelia’s proprietary ex-vivo CRISPR-Cas9-based gene editing platform and its lipid nanoparticle (LNP)-based technologies for the discovery & development of five allogeneic NK cell therapies.
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Rising Demand for Gene Editing in Drug Discovery & Development
Drug discovery, where new drug candidates are discovered and evaluated for therapeutic use, provides promising and life-saving therapies for many diseases, including hereditary and pathogenic infectious diseases. However, finding and testing new drug candidates typically takes more than a decade, and the cost of the drug discovery process can exceed $ 1 billion. In the US, the drug discovery process takes an average of 12 years and over $1 billion to develop new drugs. The chances of a new drug hitting the market are only one in 5,000. The high cost and time required to bring a new drug into the market make the drug development process challenging for pharmaceutical companies, thus slowing the discovery and development of new therapies.
There are high expectations that direct genome manipulation may revolutionize the drug discovery process with the advent of the latest genome editing technologies and understanding the human genome sequence. Emerging technologies, such as CRISPR-Cas9, are key to unlocking potential drug discovery targets and can significantly impact modern drug discovery and development. CRISPR is a genome editing technology that lets scientists precisely modify parts of the DNA sequence in the genome of any organism.
Market Segmentation
Therapy Type: Gene Therapy and Cell Therapy
Application: Oncology, Genetic Disorders, Dermatology Disorders, Musculoskeletal Disorders, and Others)
End-Users: Hospitals, Cancer Care Centers, Wound Care Centers, and Others)
Geography: North America, Europe, APAC, Latin America, and the Middle East & Africa)
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