(Albany, USA) DelveInsight’s, “Cryopyrin-Associated Periodic Syndrome Pipeline Insight 2023” report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Cryopyrin-Associated Periodic Syndrome (CAPS) pipeline landscape. It covers the Cryopyrin-Associated Periodic Syndrome pipeline drug profiles, including Cryopyrin-Associated Periodic Syndrome clinical trials and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.
For Cryopyrin-Associated Periodic Syndrome Emerging Drugs the Cryopyrin-Associated Periodic Syndrome Pipeline analysis report provides a 360° view of the Cryopyrin-Associated Periodic Syndrome pipeline therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The Cryopyrin-Associated Periodic Syndrome pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.
Key Takeaways from the Cryopyrin-Associated Periodic Syndrome Pipeline Report
- Over 4+ Cryopyrin-Associated Periodic Syndrome companies are evaluating 4+ Cryopyrin-Associated Periodic Syndrome pipeline therapies in various stages of development, and their anticipated acceptance in the Cryopyrin-Associated Periodic Syndrome market would significantly increase market revenue.
- The leading Cryopyrin-Associated Periodic Syndrome Companies include Zydus Cadila, Novartis, Inflazome, Roche, Aclaris Therapeutics, Mabpharm, Regeneron Pharmaceuticals, and others.
- Promising Cryopyrin-Associated Periodic Syndrome Pipeline Therapies include ACZ885, rilonacept 160 mg, Canakinumab (ACZ885), ZYIL 1, DFV890, Zunsemetinib, IZD334, and others.
- The Cryopyrin-Associated Periodic Syndrome Companies and academics are working to assess challenges and seek opportunities that could influence Cryopyrin-Associated Periodic Syndrome R&D. The Cryopyrin-Associated Periodic Syndrome pipeline therapies under development are focused on novel approaches to treat/improve Cryopyrin-Associated Periodic Syndrome.
- Aclaris is developing zunsemetinib as a potential treatment for RA and other immuno-inflammatory diseases. Currently the drug is in phase 2 stage of development for the treatment of Cryopyrin-associated periodic syndromes.
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Cryopyrin-Associated Periodic Syndrome Overview
Cryopyrin-associated periodic syndrome or syndromes (CAPS), also known as cryopyrinopathies, are genetic autoinflammatory syndromes defined by ‘gain-of-function’ mutations affecting the cryopyrin protein. Cryopyrin-associated periodic syndromes are all autosomal dominant genetic conditions, meaning only one copy of the abnormal gene is required to develop the clinical syndrome.
Cryoprin-Associated Periodic Syndrome Emerging Drugs
- ZYIL 1 : Zydus Cadila
ZYIL1 is a novel oral small molecule NLRP3 inhibitor. It was found to be safe and well-tolerated in Phase I trials. Currently, it is in Phase II stage of development to treat Cryopyrin-associated periodic syndromes.
- DFV890: Novartis Pharmaceuticals
DFV 890 is a NLRP3 protein inhibitor being developed by Novartis. Currently, it is in Phase II stage of development to treat Cryopyrin-associated periodic syndromes.
- Zunsemetinib : Aclaris Therapeutics
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated protein kinase 2 (MK2) inhibitor. This mechanism potentially leads to the inhibition of multiple cytokines, chemokines, matrix metalloproteases and other inflammatory signals. Key inflammatory cytokines driven by this mechanism include tumor necrosis factor α (TNFα) and interleukin-1α, -1β, -6 and -8 (IL1α, IL1β, IL6 and IL8). Aclaris is developing zunsemetinib as a potential treatment for RA and other immuno-inflammatory diseases. Currently the drug is in phase 2 stage of development for the treatment of Cryopyrin-associated periodic syndromes.
- IZD334: Inflazome
IZD334 is a NLRP3 protein inhibitors. Activated NLRP3 acts as a ‘danger sensor’ in the body to release the pro-inflammatory cytokines IL-1β, IL-18 and induce uncontrolled, lytic cell death (pyroptosis). These processes lead to chronic inflammation, and as such, NLRP3 has been implicated in a large number of diseases. Acquisition of Inflazome had given Roche full rights to the Inflazome portfolio.
Find out more about the Cryopyrin-Associated Periodic Syndrome Diagnosis and Treatment of patients @ Cryopyrin-Associated Periodic Syndrome Ongoing Clinical Trials Analysis
Cryopyrin-Associated Periodic Syndrome Companies
- Zydus Cadila
- Novartis
- Inflazome
- Roche
- Aclaris Therapeutics
- Mabpharm
- Regeneron Pharmaceuticals, and others
Cryopyrin-Associated Periodic Syndrome Pipeline Therapies
- ACZ885
- rilonacept 160 mg
- Canakinumab (ACZ885)
- ZYIL 1
- DFV890
- Zunsemetinib
- IZD334, and others
Cryopyrin-Associated Periodic Syndrome Pipeline: Phases
- Late stage products (Phase III)
- Mid-stage products (Phase II)
- Early-stage product (Phase I) along with the details of
- Pre-clinical and Discovery stage candidates
- Discontinued & Inactive candidates
Route of Administration
- Intra-articular
- Intraocular
- Intrathecal
- Intravenous
- Ophthalmic
- Oral
- Parenteral
- Subcutaneous
- Topical
- Transdermal
Molecule Type
- Oligonucleotide
- Peptide
- Small molecule
Discover more about the list of Cryopyrin-Associated Periodic Syndrome FDA-approved drugs @ Cryopyrin-Associated Periodic Syndrome Treatment Landscape
Scope of the Cryopyrin-Associated Periodic Syndrome Pipeline Report
- Coverage- Global
- Cryopyrin-Associated Periodic Syndrome Companies- Zydus Cadila, Novartis (NYSE: NVS), Inflazome, Roche (NYSE: ROG.SW), Aclaris Therapeutics (NYSE: ACRS), Mabpharm, Regeneron Pharmaceuticals (NYSE: REGN), and others.
- Cryopyrin-Associated Periodic Syndrome Pipeline Therapies- ACZ885, rilonacept 160 mg, Canakinumab (ACZ885), ZYIL 1, DFV890, Zunsemetinib, IZD334, and others
- Cryopyrin-Associated Periodic Syndrome Pipeline Segmentation: Product Type, Molecule Type, Mechanism of Action, Route of Administration
Dive deep into rich insights for Cryopyrin-Associated Periodic Syndrome Emerging Therapies and Ongoing Clinical Trials; visit @ Cryopyrin-Associated Periodic Syndrome Pipeline Therapies and Companies
Table of Content
- Introduction
- Executive Summary
- Cryoprin-Associated Periodic Syndrome: Overview
- Pipeline Therapeutics
- Therapeutic Assessment
- Cryoprin-Associated Periodic Syndrome– DelveInsight’s Analytical Perspective
- Late Stage Products (PhaseIII)
- Drug Name : Company Name
- Drug profiles in the detailed report…..
- Mid Stage Products (Phase II)
- ZYIL1: Zydus Cadila
- Drug profiles in the detailed report…..
- Early Stage Products (Phase I)
- IZD334: Inflazome
- Drug profiles in the detailed report…..
- Preclinical and Discovery Stage Products
- Drug name: Company Name
- Drug profiles in the detailed report…..
- Inactive Products
- Cryoprin-Associated Periodic Syndrome Key Companies
- Cryoprin-Associated Periodic Syndrome Key Products
- Cryoprin-Associated Periodic Syndrome- Unmet Needs
- Cryoprin-Associated Periodic Syndrome- Market Drivers and Barriers
- Cryoprin-Associated Periodic Syndrome- Future Perspectives and Conclusion
- Cryoprin-Associated Periodic Syndrome Analyst Views
- Cryoprin-Associated Periodic Syndrome Key Companies
- Appendix
For further information on the Cryopyrin-Associated Periodic Syndrome Pipeline therapeutics, reach out @ Cryopyrin-Associated Periodic Syndrome Market Drivers and Barriers
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