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The other name of generic chronic obstructive pulmonary disorder is Alpha-1 Antitrypsin Deficiency (Alpha-1). This disorder gets transmitted from the parentages to their young ones (offspring) by means of DNA. Genes can be regarded as a type of coding or a set of instructions that the cell of the human body monitors to give features such as black hair, blue eyes etc. Sometimes, we talk about a certain feature which we inherit from our parents, sometimes from mother or sometimes from father, like skin tone or other feature that is inherited from them through genes. This is often called the genetic trait inherited. One such disease is the Alpha-1 lung disease that is very often mentioned as genetic COPD as it is genetic in nature. The disease, Alpha-1 consists of two broken-down genes, derived uniquely from the parents. The genes named, Z and S are the prominent abnormal genes present. Preliminary analysis of alpha-1 often has asthma or the chronic obstructive pulmonary disease which is caused due to smoking. The other two types of COPD are chronic bronchitis and Emphysema. The most common hereditary factor of risk for the aforesaid generic disorder is alpha-1. Alpha-1 is sometimes found in 3% of person having COPD and did not undergo the test.
According to the research report, the global Genetic chronic obstructive pulmonary disease (COPD) market was valued at US$ 560.3 Million in 2022 and is expected to reach US$ 720.5 Million by 2030, to grow at a CAGR of 3.2% during the forecast period.
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Growing incidence of COPD is anticipated to boost the genetic COPD growth of the market worldwide in the predicted period. For example, in May 2022, as per the fact sheet issued by WHO (World Health Organization), COPD (chronic obstructive pulmonary disease) ranks third in the reason of causing death issued by the National Heart, Lung and Blood Institute, every November, the community of COPD congregates in promoting superior understanding of COPD. Chronic obstructive pulmonary disease is an advanced disease of the lungs that impacts on a great mass of people in the United States. Growing consciousness about COPD and its indications is vital as initial analysis and cure can develop the standard of living.
Growing R&D activities by the main market players for the progress of the consciousness and introduction of the product is anticipated to push the genetic COPD growth of the market worldwide. For example, Verona Pharma is a medical company which announced in June 2022 the closure of the enrolment of the patient, with over 800 subjects engaged for its randomized ENHANCE-1 trial. Assessment of ensifentrine in maintaining the treatment of COPD will be done in the study. The step is a complicated one in phase III ENHANCE trial with top-line data anticipated by 2022 and more data from ENHANCE-2 in the third quarter of 2022.
Furthermore, Verona Pharma which is a medical company that started a new phase IIb in May 2019, a clinical trial to evaluate nebulized ensifentrine (RPL554), in a blend with a long-term bronchodilator in treating mild to severe COPD.
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As the pandemic of COVID-19 and its outbreak in December 2019, the disease made its presence in more than 100 countries worldwide and WHO declared it as a situation of public health emergency on 30th January 2020.
Though, the pandemic of COVID-19 had a constructive effect on the genetic COPD (chronic obstructive pulmonary disease) worldwide, due to the rising need of drugs in treating COPD among patients with the infection of COVID-19. For example, as per an article issued by the National Center for Biotechnology Information, offering access to genomic and biomedical information in February 2022, chronic respiratory diseases (CRDs) impacts the airways and also the lung’s structures, lungs dysfunction is seen in the patients affected by coronavirus. The coronavirus infected patients’ shows symptoms like insufficient oxygen rich blood supply to lungs and body, difficulty in breathing as in COPD. Need for drugs used in treating COPD have been augmented in the first wave of COVID-19 as there was unavailability of drug therapy treatment for coronavirus. COPDs drug therapy treatment was used for treating coronavirus in the initial phase.
Alembic Pharmaceuticals Ltd is a medical company that got the final consent in May 2022 from the United States health controller for its standard form of Arformoterol Tartrate inhalation solution directed for treating long-term bronchoconstriction in patients having COPD. The consent by the United States FDA (Food and Drug Administration) for the abbreviated new drug application (ANDA) for Arformoterol Tartrate inhalation solution is for power of 15 mcg (base)/2 mL unit-dose vial.
The main factors that hamper the market of the generic COPD (chronic obstructive pulmonary disease) and its growth worldwide include that the new drugs’ development is a stimulating task and failure of drugs or termination in the clinical trials. For example, asthma drug benralizumab failed to reduce the yearly COPD exacerbation rates for patients with mild to very serious COPD in May 2019. The Phase III trial is a random, placebo-controlled, double-blind, parallel-group medical trials GALATHEA and TERRANOVA assessed the efficiency and safety of benralizumab in preventing exacerbations among patients with mild to serious chronic obstructive pulmonary disease.
The main companies participating in the market of genetic COPD worldwide are GSK Plc, AstraZeneca Plc, Merck (Sigma-Aldrich), Dey Pharma, Grifols, S.A., Teva Pharmaceutical Industries Ltd, Baxter, Boehringer Ingelheim International GmbH, Kamada Ltd, Takeda Pharmaceutical Company Limited, LFB SA, Abeona Therapeutics, Alnylam Pharmaceuticals, Inc., Vertex Pharmaceuticals Incorporated, Kedrion S.p.A., and Arrowhead Pharmaceuticals, Inc.
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Table of Contents
- Research Objectives and Assumptions
- Research Objectives
- Assumptions
- Abbreviations
- Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Market Snapshot, By Drug Class
- Market Snapshot, By Route Of Administration
- Market Snapshot, By Distribution Channel
- Market Snapshot, By Region
- Coherent Opportunity Map (COM)
- Report Description
- Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Drivers
- Restraints
- Market Opportunities
- Regulatory Scenario
- Key Highlights
- Research and Development Collaboration, Mergers, and Acquisitions
- PEST Analysis
- Pipeline Analysis
- Epidemiology
- Market Dynamics
- Global Genetic Chronic Obstructive Pulmonary Disease (COPD) Market – Impact of Coronavirus (Covid-19) Pandemic
- Overall Impact
- Government Initiatives
- COVID-19 Impact on the market
- Global Genetic Chronic Obstructive Pulmonary Disease (COPD) Market, By Drug Class, 2017 – 2030, (US$ Million)
- Overview
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Bronchodilators
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Phosphodiesterase Type 4 Inhibitors
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Steroids
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Antibiotics
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Others
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Overview
- Global Genetic Chronic Obstructive Pulmonary Disease (COPD) Market, By Route Of Administration, 2017 – 2030, (US$ Million)
- Overview
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Oral
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Nasal
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Overview
- Global Genetic Chronic Obstructive Pulmonary Disease (COPD) Market, By Distribution Channel, 2017 – 2030, (US$ Million)
- Overview
- Market Share Analysis, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Hospital Pharmacies
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Retail Pharmacies
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Online Pharmacies
- Overview
- Market Size and Forecast, and Y-o-Y Growth, 2017–2030, (US$ Million)
- Overview
- Global Genetic Chronic Obstructive Pulmonary Disease (COPD) Market, By Region, 2017 – 2030, (US$ Million)
- Introduction
- Market Share Analysis, By Region, 2023 and 2030 (%)
- Y-o-Y Growth Analysis, For Regions, 2017–2030
- Regional Trends
- North America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 – 2030, (US$ Million)
- U.S.
- Canada
- Latin America
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 – 2030, (US$ Million)
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Europe
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 – 2030, (US$ Million)
- U.K.
- Germany
- Italy
- France
- Spain
- Russia
- Rest of Europe
- Asia Pacific
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 – 2030, (US$ Million)
- China
- India
- Japan
- ASEAN
- Australia
- South Korea
- Rest of Asia Pacific
- Middle East
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country, 2017 – 2030, (US$ Million)
- GCC
- Israel
- Rest of Middle East
- Africa
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, By Drug Class, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Route Of Administration, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Distribution Channel, 2017 – 2030, (US$ Million)
- Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2017 – 2030, (US$ Million)
- North Africa
- Central Africa
- South Africa
- Introduction
- Competitive Landscape
- Heat Map Analysis
- Company Profiles
- GSK Plc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- AstraZeneca Plc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Merck (Sigma-Aldrich)
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Dey Pharma
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Grifols, S.A.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Teva Pharmaceutical Industries Ltd
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Baxter
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Boehringer Ingelheim International GmbH
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Kamada Ltd
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Takeda Pharmaceutical Company Limited
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- LFB SA
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Abeona Therapeutics
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Alnylam Pharmaceuticals, Inc.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Vertex Pharmaceuticals Incorporated
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Kedrion S.p.A.
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- Arrowhead Pharmaceuticals, Inc
- Company Highlights
- Product Portfolio
- Key Highlights
- Financial Performance
- Market Strategies
- GSK Plc
- Section
- References
- Research Methodology
- About Us and Sales Contact
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