Developments in 3D printing have significantly altered the competitive landscape across many market segments, from the automation sector to the healthcare sector. The healthcare sector is being revolutionized by 3D printing of organs, the next generation of organ transplantation technology. This multimillion-dollar market is expanding at a healthy double-digit rate, giving medical businesses plenty of room to grow. Over the past five years, there has been a rising demand for organ transplants. Nearly 121 thousand people in the United States are on organ transplant waiting lists, according to the U.S. National Kidney Foundation. Eighty percent of these people are in need of a kidney transplant. In the last 28 years, the United States has seen over than 650 thousand transplants. The numbers, however, stand in stark contrast to actual demand, and a massive gap exists among both demand and supply of organs. Unfortunately, only 2% of patients receive transplants. A lot of emphasis has been put on the development of methods to artificially build organs that can save lives due to the increasing demand. Therefore, numerous businesses working in tandem with research facilities are developing 3D printed organs.
Vascular grafts, heart tissue, tracheal splints etc., will all be printed in 3D and transplanted in the near future, ushering in a new era of medicine. Those who enter the market early will have a leg up on the competition, which will boost their revenue to a greater degree.
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High demand for organs that can save lives, combined with shifting healthcare macroeconomics, suggests a bright future for 3D printed functional tissue. In order to meet the rising demand of millions of people seeking organ transplants, many university labs like the Wake Forest Institute for Regenerative Medicine and Harvard scientists in partnership with prominent medical device companies are holding out projects to develop lab-grown tissue. Technology like 3D printing has helped close the gap significantly. Market growth is also being fueled by rising healthcare spending and a larger consumer base.
Although there is optimism in the market, the industry is facing obstacles, such as the high cost of research and development results and regulatory pressures. It will require at least seven years for the technology to reach full commercialization, which will lead to steep operating expenses. The pressure on the industry might be reduced if the government provided funding.
Organ transplants, dental work, and biosensors are the three main categories into which 3D printed functional tissue falls. Over 65% of the market is expected to come from the organ transplant application segment by the end of the forecast period.
During the forecast period, North America and Europe are anticipated to account for a bulk of the market share. Because of its abundance of industry leaders and heavy investment in R&D, North America is anticipated to expand at the quickest rate worldwide. Also, in the last five years, more organ transplant surgeries have been performed in this area than anywhere else in the world.
According to CA’s preliminary research, the markets in North America and Europe will make up more than 85% of the global functional 3D printed tissue market by 2025. In order to keep up with the rising national demand for organ transplants, healthcare providers are looking into this technology. Macroeconomic factors are widely anticipated to play an even greater role in fueling growth in these areas. As a whole, the region invests more than 5% of its GDP in science and education. And in 2015, healthcare expenditures accounted for 16.7% of North American GDP and 10% of European GDP, making this region the world leader in healthcare spending.
Australia and Japan are seen as the region’s main drivers. The donation rate in Australia is close to 17 people per million, according to Organdonor. The country has made significant strides in the study of 3D bioprinting. The Menzies Institute at Griffith University is making progress towards 3D printing tissue and bones with funding from the National Health and Medical Research Council. More importantly, the bioprinting market will receive a boost in the near future thanks to an initiative taken by the Australian government to establish a US$2.7 Mn bioprinting centre. The local market is predicted to become fully commercialized within the next 15 years. This area is in its infancy, and it will be many years before it can support a commercial economy. Prior to the end of the predicted period, the majority of projects will have only completed their feasibility studies.
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The main companies involved in functional 3D Printed Tissue Market includes Aspect Biosystems, BioBots TeVido, Organovo, Cyfuse Biomedical, 3Dynamics Systems, Luxexcel Group, Stratasys, EnvisionTEC, etc.
There is a concentrated effort among market leaders to secure capital for product diversification. For example, in July of this year, the U.S.-based biotechnology firm Prellis Biologics raised US$8.7 million to further develops its holographic 3D bioprinting platform.
The 3D printing of tissues is also a topic of research and development at major institutes. In August, for example, scientists from EPFL’s Laboratory of Applied Photonics Devices (LAPD) and Utrecht University reported the development of a method called volumetric bioprinting to create complex tissue forms in hydrogels that are loaded with stem cells to produce growth of blood vessels in the resulting tissue mass.
In a similar vein, in April 2019, scientists at the Indian Institute of Technology in Hyderabad, India, fabricated 3D scaffolds out of waste eel skins for use in tissue engineering.
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