Live Attenuated Vaccines Market
Live Attenuated Vaccines are vaccines developed by lowering pathogen pathogenicity (LAV). These pathogens are attenuated in the laboratory. The vaccination stimulates an aggressive immune response against infectious illnesses. They begin the formation of memory cells in order to respond to the virus that has already entered the body. The market for live attenuated vaccines is expanding due to increased vaccination awareness, increased government financing for immunization programmes, and the increasing occurrence of infectious illnesses. Improving healthcare infrastructure, rising demand for LAV, and a focus on illness prevention are further driving this market.
Market Size and Future Apprehension:
According to the most recent DataM Intelligence analysis, the worldwide “Live Attenuated Vaccines Market” is expected to grow at a CAGR of 10.4% during the forecast period 2022-2029.
Live-attenuated vaccines are very effective vaccines used in the prevention of a variety of diseases including influenza, chickenpox, measles, polio, and TB. Live-attenuated vaccines differ from traditional inactivated vaccines where the pathogen is “killed”, and as the name suggests the pathogen (typically a virus) remains active in live vaccines, however, is attenuated or modified in a way that the pathogen is not able to cause disease itself but can produce a robust immune response.
- There is growing evidence of live attenuated vaccine delays or refusals due to a lack of trust in the importance, safety, or effectiveness of vaccines, alongside persisting access issues.
- The Vaccine Confidence Project (VCP) has conducted numerous surveys, focussed groups, in-depth qualitative research, and large-scale digital media analytics, as well as convened expert roundtables and workshops to understand context-specific attitudes to vaccines among the general public.
- The VCP continues to research the roots, trends, and impacts of vaccine confidence issues at national and supranational levels to inform policy and trust-building activities and mitigate the need for crisis management in immunization programs.
There has also been a general consolidation of the worldwide vaccine industry, reflected by strategic alliances between and among companies on both sides of the Atlantic. According to industry officials, these mergers are driven largely by the desire to access technology and share intellectual property in order to develop combination vaccines.
Key Insight- Live Attenuated Vaccines Market
- Live-attenuated measles virus (MeV) has been extraordinarily effective in preventing measles infections and their often-deadly sequelae, accompanied by remarkable safety and stability.
- Although improved sanitation and antibiotics may have saved more lives, vaccines represent the most cost-effective life-saving device in history. Despite their success, one of the great ironies of vaccinology is that the vast majority of vaccines have been developed empirically, with little or no understanding of the immunological mechanisms by which they induce protective immunity.
- However, the failure to develop vaccines against global pandemics such as infection with human immunodeficiency virus (HIV) despite decades of effort has underscored the need to understand the immunological mechanisms by which vaccines confer protective immunity.
- In November 07, 2022- Rotarix (Rotavirus Vaccine, Live, Oral), which protects against rotavirus gastroenteritis brought on by G1 and non-G1 types (G3, G4, and G9) in infants, received FDA approval for an oral-dosing applicator-only presentation (liquid formulation). By eliminating the requirement to reconstitute the vaccine dose at the point of use, this new presentation formulation aims to make it more convenient for healthcare professionals to prepare Rotarix.
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One of the primary factors driving the growth of the live attenuated vaccines market is the increase in the number of individuals suffering from infectious illnesses throughout the world. The rise in demand for illness-specific new treatments for various disease complications, as well as the rise in demand for programmes aimed at preventing transmission and alleviating suffering, drive market expansion. The increase in the number of clinical trials done by numerous pharmaceutical businesses, as well as activities by public and private groups to produce improved medications, all have an impact on the market.
Limited operational revenue for innovative medication research and development, as well as hefty development costs, are projected to stymie industry expansion. Low healthcare budgets, particularly in emerging nations, and low awareness are expected to provide challenges to the market for live attenuated vaccines during the forecast period.
During the analysis period, the increase in demand for innovative treatments creates profitable opportunities for market participants.
The global Live Attenuated Vaccines Market segmented into by type, age group, end user, region
By Age Group:
By End User:
- Research Institutes
- North America
- Latin America
- Asia Pacific
- Middle East and Africa
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The market for live attenuated vaccines is highly competitive, with a significant number of current major players and minor sellers. Among the top companies in the worldwide market for live attenuated vaccines are
- Merck & Co. Inc
- GlaxoSmithKline plc
- Pfizer Inc
- Astellas Pharma
- CSL Limited
- Serum Institute of India Pvt. Ltd
- Emergent BioSolutions Inc
- Vivaldi Biosciences Inc
The leading players are implementing different growth strategies such as product launches, mergers and acquisitions, partnerships, and collaborations, which are helping to drive the worldwide expansion of the live attenuated vaccines market.
Globally, Live Attenuated Vaccines Market consists of North America, Latin America, Europe, Asia Pacific, Middle East and Africa regions. North America is the world’s largest market. Government initiatives for disease vaccination, such as influenza, as well as good management of public awareness campaigns, are encouraging the growth of this market in North America. Because of the availability of finances for R&D operations and the increased emphasis on R&D, Europe is the second biggest market. Due to a rise in the frequency of communicable illnesses, Asia Pacific is seeing the highest growth in this market.
- Codagenix Inc., a clinical-stage synthetic biology company with a rational vaccines design platform aimed at infectious diseases and cancer, announced in May 2022, in collaboration with the Serum Institute of India Pvt. Ltd., that the first patient had been dosed in a U.K.-based Phase 1 clinical trial to evaluate the use of Codagenix’s novel intranasal, live-attenuated virus vaccines, CoviLiv, as a booster in.
- Jynneos, a live attenuated vaccine, to be launched in May 2022 by the European biotech business Bavarian Nordic. Immunity against smallpox and monkeypox is provided by the vaccinations. Furthermore, antibiotics and hydration treatment are used to treat the symptom.
Pediatric Vaccines Market is segmentation By Disease type (Infectious Diseases (Polio, Influenza, Measles, Mumps and Rubella (MMR), Pneumococcal disease, Human papillomavirus, Hepatitis, Others), Allergies), By Vaccine Type (Monovalent Vaccines, Multivalent Vaccines), By Technology (Live attenuated Vaccines, Inactivated Vaccines, Sub-unit Vaccines, Toxoid Vaccines, Conjugate Vaccines, Others), and By Region (North America, Latin America, Europe, Asia Pacific, Middle East, and Africa) – Share, Size, Outlook, and Opportunity Analysis, 2022-2029
Japanese Encephalitis Vaccines Market is segmented By Type (Inactivated Vero Cell-derived Vaccines, Live Attenuated Vaccines, Inactivated Mouse Brain-derived Vaccines, Live Recombinant Vaccines), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies), and By Region (Akita, Aomori, Chiba, Fukui, Fukuoka, Others) – Share, Size, Outlook, and Opportunity Analysis, 2022-2029