The Insight Partners published latest research study on “Organoids Market Forecast to 2027 – COVID-19 Impact and Global Analysis – by Type, Application, and Source,” the global organoids market was values US$ 689.47 million in 2019 and is expected to reach US$ 3,420.40 million by 2027. The market is estimated to grow at a CAGR of 22.1% from 2020 to 2027.
Organoids are tiny, self-organized, three-dimensional tissue cultures that are derived from stem cells. Such cultures can be crafted to replicate much of the complexity of an organ, or to express selected aspects of it like producing only certain types of cells. Organoids grow from stem cells—cells that can divide indefinitely and produce different types of cells as part of their progeny. Organoids can range in size from less than the width of a hair to five millimeters.
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Organoids Market: Competition Landscape and Key Developments
Major primary and secondary sources included in the report are STEMCELL Technologies, Inc.; Cellesce Ltd.; Hubrecht Organoid Technology; Definigen; 3Dnamics, Inc.; Organoid Therapeutics; PeproTech, Inc.; Thermo Fisher Scientific; Corning Incorporated (Life Sciences); and Merck KGgA.
The market players are focused toward bringing new and innovative products and services to sustain their position in the market. For instance, in January 2020 Merck and BioMed X0020collaborated a for new research program in autoimmune diseases. This research would involve use of conventional and high-throughput metagenomics and generation of intestinal organoids from murine and human subjects for identification of biomarkers of autoimmune diseases. Such developments are expected to boost the market growth during the forecast period.
Browse key market insights spread across 174 pages with 84 list of tables & 77 list of figures from the report, “Organoids Market Forecast to 2027 – COVID-19 Impact and Global Analysis By Type (Stomach, Intestine, Liver, Pancreas, Lung, Brain, Kidney, Others); Application (Developmental Biology, Disease Pathology of Infectious Disease, Regenerative Medicine, Drug Toxicity and Efficacy Testing, Drug Discovery and Personalized Medicine, Others); Source (Pluripotent Stem Cells, Organ-specific Adult Stem Cells), and Geography” in detail along with the table of contents: https://www.theinsightpartners.com/reports/organoids-market
Increasing demand for tumor modelling and biobanking, rising adoption of personalized drugs, and growing focus on developing alternatives for animal testing models are anticipated to drive the market. However, issues related to the incorporation of organoids into existing workflows and dearth of skilled professionals are likely to pose a negative impact on the market growth.
Organoids are microscopic and self-organizing 3D structures, which are grown from stem cells in vitro. They review various structural and functional characteristics of their in vivo counterpart organs. This multipurpose technology has led to the development of several novel human cancer models. It is now possible to create indefinitely expanding organoids starting from the tumor tissue of individuals suffering from a range of carcinomas. Alternatively, CRISPR-based gene modification allows the engineering of organoid models of cancer by introducing any combination of cancer gene alterations to normal organoids. Tumor organoids, when combined with immune cells and fibroblasts, become a model for the cancer microenvironment enabling immune-oncology applications. Also, recent studies have proved that organoids have a place in personalized medicine approaches.
The constant progress in organoid technology has paved the way for tumors and patient-centric 3D cultures of cells isolated from tumor biopsies. Over the past few decades, organoids have been generated from diverse human cancers, related to breast, colon, pancreas, prostate, bladder, and liver. Studies involving these models are increasing knowledge of the etiology and features of these malignancies. Due to constant advancements, in the current scenario, tumoroid lines are increasingly being passed in vitro, which opens up new paths for a range of downstream applications. Moreover, 3D-based cultures offer added advantages over the conventional 2D cancer-derived cell lines. Further, research and development activities have specified that tumoroid culturing is highly effective in allowing the collection of various cancer subtypes from a large pool of patients. As organoids can be easily derived and expanded from single cancer cells, the adoption of organoids to mimic intratumor diversification in culture is increasing, which, in turn, is projected to propel the global organoids market during the forecast period.
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Impact of COVID-19 on Organoids Market
The emergence of coronavirus pandemic is estimated to have a significant impact on the organoids market. Majority of the pharmaceutical companies around the globe are engaged in the development of vaccine for coronavirus. Moreover, COVID-19 has also caused increased interest in human lung organoid models. However, this shift of focus is anticipated to have a positive impact on the other segments of the market. Disruptions in supply chain caused due to halt in global operations are projected to have an adverse impact on the market.
The report highlights the trends prevalent in the global organoids market and the factors driving the market along with those that act as deterrents to its growth. The market is expected to grow due to increasing demand for tumor modelling and biobanking, rising adoption of personalized drugs, and growing focus on developing alternatives for animal testing models.
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