Certain immune and non-immune cells produce cytokines, a class of protein that has an impact on the immune system. Some cytokines speed up the immune system while others suppress it. The body may fight cancer, infections, and other diseases with the aid of cytokines. Cytokine treatment for cancer may assist the immune system in eliminating cancer cells or preventing their growth. Interleukins and interferons are the two primary categories of cytokines utilised to treat cancer. Additionally, cytokine-based medicines have the potential to offer cutting-edge treatments for a variety of infectious illnesses, autoimmune disorders, and cancer.
By the end of 2022, the worldwide cytokine market is anticipated to be worth US$ 84,704.4 Mn.
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Over the course of the projected period, an increase in cancer incidence around the world is anticipated to boost market expansion for cytokines. For instance, cytokines have been shown to be a successful cancer treatment. Cytokine treatment for cancer may assist the immune system in eliminating cancer cells or preventing their growth. Thus, the use of cytokine treatment is expanding along with the occurrence of cancer. The American Cancer Society reports that, behind heart disease, cancer continues to be the second most prevalent cause of death in the country. In the US, there will likely be 1.9 million new cancer diagnoses and 609,360 cancer-related deaths in 2022, or roughly 1,670 fatalities every day.
Players in the worldwide cytokine market may anticipate to benefit from attractive growth possibilities as the number of diagnostic, therapeutic, and prophylactic uses of cytokines rises. For instance, Sanofi said in May 2022 that the FDA had approved the supplementary Biologics License Application for Dupixent (dupilumab) to treat adults with prurigo nodularis, a persistent inflammatory skin condition that produces intense itching and skin sores. Dupixent is a completely human monoclonal antibody that does not suppress the immune system but instead blocks the signalling of the interleukin-4 and interleukin-13 pathways.
Some significant issues that are anticipated to impede the growth of the global cytokine market include high prices of cytokine-based treatments and a lack of specificity. The high cost of cytokine-based therapeutics is anticipated to restrain the growth of the worldwide cytokine market, despite the fact that cytokines have the potential to be used in a broad variety of applications, including stem cell therapy, cancer therapy, and diagnostics. Additionally, the lack of specificity might be problematic in some diagnostic situations and restrains the market’s expansion of cytokines.
A cytokine storm, also known as an immunological reaction, occurs in certain COVID-19 individuals, according to the National Institutes of Health (NIH). A cytokine storm can result in acute respiratory distress syndrome, multiple organ failure, and other potentially fatal consequences. Scientists at Sanford Burnham Prebys Medical Discovery Institute were awarded a US$ 3 million grant from the NIH in September 2020 to investigate how SARS-CoV-19 compromises the immune system and find medications to hasten the recovery of affected people. The study’s main objective is to understand how the COVID-19 coronavirus disables the antiviral cytokine pathways.
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The market for cytokines was valued at US$ 77,796.1 Mn in 2021 and is anticipated to grow at a CAGR of 8.9% from 2022 to 2028 to reach US$ 141,667.1 Mn.
Tumor Necrosis Factor-TNF maintained a prominent position in the worldwide cytokine market in 2021, accounting for 55.4% of the market’s value share.
Over the projected period, an increase in research and development is anticipated to fuel the expansion of the worldwide cytokine market. For instance, Sonnet BioTherapeutics Holdings, Inc. presented findings from preclinical tests of its patented Fully-Human Albumin Binding candidates, SON-1010, SON-1210, in April 2022.
Over the course of the projected period, an increase in product approvals is anticipated to fuel market expansion for cytokines worldwide. For example, the U.S. Food and Drug Administration (FDA) authorised Amgen’s RIABNI (rituximab-arrx) in June 2022 as a biosimilar for individuals with moderate to severely active rheumatoid arthritis (RA) who have not responded adequately to one or more tumour necrosis factor (TNF) antagonist medications.
The leading companies in the worldwide cytokine market are GlaxoSmithKline PLC, Biocon Limited, Amgen Inc., Johnson & Johnson, Novartis International AG, Abbvie Inc., Pfizer Inc., UCB S.A., Sanofi SA, and Astra Zeneca PLC.
The FDA approved GlaxoSmithKline’s Nucala to treat hypereosinophilic syndrome in September 2020. (HES). In order to alleviate the symptoms associated with HES, Nucala acts by inhibiting the protein interleukin-5 (IL-5) from attaching to eosinophil cells.
For the treatment of patients 12 years of age and older with eosinophilic esophagitis, the US Food and Drug Administration (FDA) designated Dupixent (dupilumab) as a breakthrough therapy in September 2020.
Abrocitinib, an experimental once-daily oral Janus kinase 1 inhibitor, was tested in a Phase III research to determine its safety and effectiveness in treating people with moderate to severe atopic dermatitis. The results were released by Pfizer Inc. in March 2020.
Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Cytokine Market Size Analysis from 2022 to 2028
11.6 COVID-19 Outbreak: Cytokine Industry Impact
Chapter 2 Global Cytokine Competition by Types, Applications, and Top Regions and Countries
2.1 Global Cytokine (Volume and Value) by Type
2.3 Global Cytokine (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Cytokine Sales, Consumption, Export, Import by Regions (2017-2022)
Chapter 5 North America Cytokine Market Analysis
Chapter 6 East Asia Cytokine Market Analysis
Chapter 7 Europe Cytokine Market Analysis
Chapter 8 South Asia Cytokine Market Analysis
Chapter 9 Southeast Asia Cytokine Market Analysis
Chapter 10 Middle East Cytokine Market Analysis
Chapter 11 Africa Cytokine Market Analysis
Chapter 12 Oceania Cytokine Market Analysis
Chapter 13 South America Cytokine Market Analysis
Chapter 14 Company Profiles and Key Figures in Cytokine Business
Chapter 15 Global Cytokine Market Forecast (2022-2028)
Chapter 16 Conclusions
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