Medicines based on small molecules continue to be crucial in the treatment of various sorts of diseases, including cancer disorders, infectious diseases, cardiovascular diseases, and blood diseases, despite the expansion of biologic pharmaceuticals. Injectable medicines with small molecular weights are frequently required for patient care. Small molecule injectable medications have the following benefits over biologics:
The Congressional Budget Office estimates that 84% of the pharmaceutical industry’s income in 2016 came from small molecule medications. In addition, short molecule APIs constituted the basis for five of the top ten pharmaceuticals in terms of revenue and nine of the top ten drugs in terms of prescriptions.
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By putting medicine into into the circulation, intravenous infusion has a rapid therapeutic impact. Such quick administration is required for small molecule medications to treat patients, and is most frequently required in hospitals in emergency department situations or when there are unanticipated consequences.
The most efficient method of delivery is injection or infusion when a patient is unable to swallow their prescription. Others may require parenteral administration of the APIs since the digestive system may have degraded them.
Furthermore, extremely high quality and sterility requirements are followed in the manufacturing of the injectable goods.
The COVID-19 pandemic is expected to enhance the market for small molecule injectable medications since manufacturing facilities were built during the pandemic. For instance, Lonza, a producer of nutrition, biotechnology, and pharmaceutical products, intended to invest US$ 218.6 million in the construction of a new small molecule production facility at its Visp, Switzerland, location in 2021. There will be six floors of production area in the building. Initial plans for the company included the creation of antibody-drug conjugates (ADCs), along with the required containment measures.
The market’s growth is anticipated to accelerate over the forecast period as a result of agreements that market participants are involved in entering into to develop new medications for the treatment of a variety of diseases, including oncology disorders, infectious diseases, blood diseases, and cardiovascular diseases. For instance, ViiV Healthcare paid Halozyme an upfront fee of US$ 40 million in 2021 in exchange for an exclusive licence to four HIV small and big molecule targets, and it is now required to pay up to US$ 175 million in the future for the achievement of commercial milestones for each target. Additionally, Halozyme will be eligible to collect royalties in the mid-single digits from the sales of commercially available drugs utilising the technology.
The market for small molecule injectable medications is anticipated to reach US$ 188.9 billion in 2022 and grow at a CAGR of 7.9% during the forecast period (2022-2030).
Market participants are investing in the creation of novel small molecule injectable medications. Over the course of the projected period, this is anticipated to fuel market expansion for small molecule injectable pharmaceuticals worldwide.
Investment activity among industry participants is anticipated to fuel market expansion for small molecule injectable medicines throughout the forecast period. For instance, to increase the scope of its medication delivery systems, multinational healthcare corporation Novartis AG invested in Credence MedSystems, a speciality pharmaceutical company, in January 2021. With the funds, Credence will create an injectable system that will enhance user experience and work with current biopharmaceutical procedures.
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As a consequence of major businesses’ attempts to get regulatory authority permission for their small molecule injectable drugs, it is estimated that the global market for small molecule injectable pharmaceuticals would grow throughout the projected period.
Market growth for small molecule injectable pharmaceuticals is predicted to be fueled by product approvals by industry players during the forecast period. For example, the pharmaceutical company Aurobindo Pharma Ltd. declared in August 2021 that Eugia Pharma Specialties Limited had obtained U.S. FDA approval for the use of cyclophosphamide injection in the treatment of a variety of cancers, including rhabdomyosarcoma, lung cancer, and Ewing’s sarcoma.
An increase in product recalls is likely to slow the global market for small molecule injectable medicines during the forecasted period. A number of small molecule injectable pharmaceuticals are being recalled by regulatory agencies including the U.S. FDA because they contain glass-like particles, which is expected to hinder the growth of the market for these products globally throughout the forecast period. In October 2021, the U.S. Food and Drug Administration learned that one batch of CUBICIN 500mg for intravenous usage is being recalled by Merck & Co. The commencement of CUBICIN therapy is expected to occur in a hospital or other tightly monitored healthcare environment, hence the recall is being done at the user level, including administering and hospital facilities. About 22,000 vials were subject to this recall.
The market for small molecule injectable pharmaceuticals is divided into North America, Latin America, Europe, Asia Pacific, Middle East, and Africa on the basis of region.
Due to an increase in product approvals by regulatory bodies, the North American small molecule injectable medicines market is anticipated to keep a dominating position over the projected period. For instance, the U.S. Food and Drug Administration authorised premix Norepinephrine Bitartrate in 5% Dextrose Injection in 2021, according to the U.S.-based international healthcare corporation Baxter International Inc. It is the only ready-to-use formulation that is manufactured by the manufacturer and is available in two concentrations of 8 mg/250 mL and 4 mg/250 mL.
Furthermore, the U.S. FDA approved Cabenuva as a full treatment programme for adults with HIV-1 infection have no history of treatment failure in January 2021, according to ViiV Healthcare, a pharmaceutical company that specialises in developing therapies for HIV infection.
Due to the rising incidence of chronic disorders including cardiovascular disease, Alzheimer’s disease, and hypertension, Europe is also anticipated to have considerable growth in the worldwide market for small molecule injectable pharmaceuticals. For instance, as of May 2021, the National Health Service, Scotland reported that there were around 850,000 Alzheimer’s patients in the United Kingdom, and that figure is projected to increase to one million by 2025 and to two million by 2050.
The top companies involved in the production of small molecule injectable medications are Hikma Pharmaceuticals plc., Novartis AG, Gilead Sciences, Inc., Pfizer, Inc., Amgen, Inc., Sun Pharmaceutical Industries Ltd., F. Hoffmann-La Roche AG (Genentech, Inc.), Merck & Co., Inc., Dr. Reddy’s Laboratories Ltd., Teva Pharmaceutical Industries Ltd., Sanofi S.A., Aurobindo Pharma Ltd., GlaxoSmithKline Plc., AstraZeneca Plc, Johnson & Johnson, Baxter International Inc., Cipla Limited, and Fresenius Kabi AG.
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Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Small Molecule Injectable Drugs Market Size Analysis from 2022 to 2028
11.6 COVID-19 Outbreak: Small Molecule Injectable Drugs Industry Impact
Chapter 2 Global Small Molecule Injectable Drugs Competition by Types, Applications, and Top Regions and Countries
2.1 Global Small Molecule Injectable Drugs (Volume and Value) by Type
2.3 Global Small Molecule Injectable Drugs (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Small Molecule Injectable Drugs Sales, Consumption, Export, Import by Regions (2017-2022)
Chapter 5 North America Small Molecule Injectable Drugs Market Analysis
Chapter 6 East Asia Small Molecule Injectable Drugs Market Analysis
Chapter 7 Europe Small Molecule Injectable Drugs Market Analysis
Chapter 8 South Asia Small Molecule Injectable Drugs Market Analysis
Chapter 9 Southeast Asia Small Molecule Injectable Drugs Market Analysis
Chapter 10 Middle East Small Molecule Injectable Drugs Market Analysis
Chapter 11 Africa Small Molecule Injectable Drugs Market Analysis
Chapter 12 Oceania Small Molecule Injectable Drugs Market Analysis
Chapter 13 South America Small Molecule Injectable Drugs Market Analysis
Chapter 14 Company Profiles and Key Figures in Small Molecule Injectable Drugs Business
Chapter 15 Global Small Molecule Injectable Drugs Market Forecast (2022-2028)
Chapter 16 Conclusions
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