Flumazenil is an antagonist administered intravenously or intramuscularly. In terms of medicine, it functions as a benzodiazepine antagonist and antidote. After diagnostic procedures, flumazenil is frequently used in anaesthesia to awaken the patient. Flumazenil is given intravenously, either diluted or undiluted.
Due to disruptions in the medicine supply chain, the COVID-19 pandemic is predicted to slow the growth of the worldwide flumazenil market. For instance, the successful steps implemented to stop the COVID-19 pandemic’s spread have ultimately had a negative impact on the drug supply chain, according to statistics provided by the United Nations Office on Drugs and Crime in July 2020. A global scarcity of various sorts of pharmaceuticals has been observed in a number of nations.
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Flumazenil manufacture and transportation were impacted by the supply chain, which limited the drug’s availability on the market.
The worldwide flumazenil market is anticipated to be constrained by the drug’s withdrawal from the market. For instance, in accordance with Section 506C of the Federal Food, Drug, and Cosmetic Act, the U.S. Food and Drug Administration published recommendations in March 2020 for businesses to follow when notifying FDA of the permanent halt or cessation of the manufacture of pharmaceuticals (FD&C Act). Flumazenil injectable, which was available in multi-dose vials containing 0.5 mg of the medication in 5 mL (0.1 mg/mL), has been discontinued, according to information given by the U.S. FDA.
The market for flumazenil is anticipated to reach US$ 20.528 billion in 2022 and grow at a CAGR of 2.8% over that time.
Players in the market are focusing on the introduction of new goods. Over the course of the forecast period, this is anticipated to fuel the expansion of the worldwide flumazenil market.
Market participants are introducing new products, which is anticipated to fuel market expansion for flumazenil throughout the forecast period. For instance, the drug maker Hikma Pharmaceuticals introduced Flumazenil Injection, USP 0.5 mg/5 mL in January 2018. Flumazenil Injection contains flumazenil as well as edetate disodium, acetic acid, propylparaben, hydrochloric acid, sodium chloride, sodium hydroxide, and methylparaben, as inactive components. A benzodiazepine derivative called flumazenil interferes with the effects of benzodiazepines on the central nervous system.
The world market for flumazenil is predicted to rise as more individuals suffer from anxiety disorders.
Over the projection period, an increase in the population with anxiety disorders is anticipated to fuel market expansion for flumazenil. For instance, according to statistics from the year 2017 that was released in April 2018 by the scientific online magazine Our World in Data, 284 million individuals worldwide suffered from anxiety disorders. Antidepressant medications, such as benzodiazepines, are administered for the patient to address anxiety problems. The usage of flumazenil as a general anaesthetic for patients to completely or partially reverse the sedative effects of benzodiazepines is anticipated to propel the expansion of the worldwide flumazenil market.
Over the projection period, it is anticipated that increasing Flumazenil adverse effects would restrain market expansion. For instance, usage of flumazenil results in side effects including drowsiness, neurologic effects, seizure, cardiovascular illnesses like hypertension, bradycardia, tachycardia, chest discomfort, and arrhythmias, per May 8, 2022 data from the National Institute of Health. These problems can limit the expansion of the flumazenil market globally.
The worldwide flumazenil market is divided into North America, Latin America, Europe, Asia Pacific, the Middle East, and Africa based on geography.
Due to the rise in anxiety disorders among individuals, the North American flumazenil market is anticipated to dominate other regions over the projected period. For instance, the number of individuals with symptoms of an anxiety or depressive illness grew from 36.4% to 41.5%, according to statistics from the Centers for Disease Control and Prevention that was released on March 26, 2021. Early on, patients are prescribed benzodiazepines for the treatment of anxiety disorders. People get sedative effects from benzodiazepines. For full or partial reversal of the sedative effects in patients, flumazenil is administered as a general anaesthetic.
Due to the rising incidence of liver cirrhosis, Europe is also anticipated to have considerable expansion in the flumazenil market. For instance, 2,302,171 people were diagnosed with cirrhosis between 2005 and 2018, according to data from The Lancet Regional Health – Europe that was published on November 3, 2021. Cellular degradation, inflammation, and fibrous tissue thickening are symptoms of a chronic liver illness like cirrhosis. The flumazenil market is anticipated to develop as a result of its usage in the early stages of cirrhosis therapy.
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Bedford Pharmaceuticals, Akorn-Strides, Physicians Total Care, Inc., LLC, Sandoz Canada Incorporated, Pfizer Laboratories Div Pfizer Inc., Fresenius Kabi USA, Hikma Farmaceutica, LLC, DBA HealthFirst, Mylan Pharmaceuticals, Genentech, Inc., HF Acquisition Co. LLC, General Injectables & Vaccines Inc, West Ward Pharmaceutical, and Sina Health Inc, are some of the major players operating in the global flumazenil market.
Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Flumazenil Market Size Analysis from 2022 to 2028
11.6 COVID-19 Outbreak: Flumazenil Industry Impact
Chapter 2 Global Flumazenil Competition by Types, Applications, and Top Regions and Countries
2.1 Global Flumazenil (Volume and Value) by Type
2.3 Global Flumazenil (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Flumazenil Sales, Consumption, Export, Import by Regions (2017-2022)
Chapter 5 North America Flumazenil Market Analysis
Chapter 6 East Asia Flumazenil Market Analysis
Chapter 7 Europe Flumazenil Market Analysis
Chapter 8 South Asia Flumazenil Market Analysis
Chapter 9 Southeast Asia Flumazenil Market Analysis
Chapter 10 Middle East Flumazenil Market Analysis
Chapter 11 Africa Flumazenil Market Analysis
Chapter 12 Oceania Flumazenil Market Analysis
Chapter 13 South America Flumazenil Market Analysis
Chapter 14 Company Profiles and Key Figures in Flumazenil Business
Chapter 15 Global Flumazenil Market Forecast (2022-2028)
Chapter 16 Conclusions
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