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Glioblastoma Pipeline Analysis: Key Pharma Players Set to Develop Novel Therapies and Explore Countless Opportunities

July 14th, 2022 DelveInsight Business Research Releases

DelveInsight’s ‘Glioblastoma Pipeline Insight 2022‘ report provides comprehensive global coverage of available, marketed, and pipeline glioblastoma therapies in various stages of clinical development, major pharmaceutical companies are working to advance the pipeline space and future growth potential of the glioblastoma pipeline domain.

For glioblastoma emerging drugs, the glioblastoma pipeline analysis report provides a 360° view of the therapeutics landscape by development point, product type, route of administration, molecule type, and MOA. The pipeline research covers business opportunities, challenges, future partnerships, strong competitors, and growth strategies.

Some of the Key Highlights from Glioblastoma Pipeline Report

  • Over 100+ glioblastoma pipeline therapies are in various stages of growth, and their anticipated acceptance in the glioblastoma market would significantly increase market revenue.
  • Leading glioblastoma companies such as Array Biopharma, AstraZeneca, Doule bond Pharmaceuticals, Philogen, Immatics N.V, BioNTech, InovioPharma, Noxxon Pharma, Celgene Corporation, Karyo Pharma, Neugate Theranostics, Novartis, Orphelia Pharma, Merck, Acerta Pharma, Genenta Science, CNS Pharmaceutical, Pfizer, Roche, Oncotelic Therapeutics, Autotelic Therapeutics, ACADIA Pharmaceuticals, Mayo Clinic, Cytogel, Xgene Pharmaceutical, Ascletis, 3-V Biosciences, Yumanity Therapeutics, and others are evaluating novel glioblastoma treatment drugs candidate to improve the treatment landscape.
  • Key glioblastoma pipeline therapies in various stages of development include Onfekafuspalfa, PLX3397, APVAC1, INO5401, Olaptesed pegol, Selinexor, L19TNF, H1PV, NG101m, ACP196, Temferon, Berubicin Hydrochloride, VXM01, Avelumab, Trabedersen, TVB2640, AZD1390, YTX7739, WP1122, and others.
  • Out of the emerging glioblastoma therapies, Trabedersen is in Phase III of clinical development, whereas, Selinexor is in Phase II stage of trials. 
  • Glioblastoma pipeline therapies in the early stage of development include AZD1390 in Phase I of clinical trials.

Request a sample and discover the recent advances in glioblastoma treatment @ Glioblastoma Pipeline Insight and Outlook

Glioblastoma Overview

Glioblastoma is a deadly form of cancer that can develop in the brain or spinal cord. Glioblastoma develops from astrocytes, which are cells that nourish nerve cells. It can develop at any age, but it is more common in elderly persons. It can aggravate headaches, nausea, vomiting, and seizures. The glioblastoma causes are unknown. 

Glioblastoma symptoms vary according to tumor type, as well as tumor size, location, and rate of growth. Glioblastoma symptoms include headache, nausea or vomiting, confusion or deterioration in brain function, memory loss, personality changes or irritability, and difficulties balancing. Computed tomography (CT or CAT scan) and magnetic resonance imaging (MRI) are two diagnostic instruments (MRI) widely used for glioblastoma diagnosis. Glioblastoma treatments may slow the progression of cancer and reduce signs and symptoms.

For more information about the disease, causes, and treatment, visit: Glioblastoma Pipeline Landscape

Glioblastoma Pipeline Analysis: Drug Profile

TVB2640:Ascletis Pharma

TVB2640 is an oral, selective fatty acid synthase (FASN) inhibitor. By inhibiting novo lipogenesis, TVB2640 reduces energy supply and disrupts membrane phospholipid composition in tumor cells (DNL). FASN is a critical enzyme that regulates DNL. It is currently in Phase III development for the glioblastoma treatment.

Trabedersen: Oncotelic Therapeutics

Trabedersen is an antisense TGF-2 inhibitor used to treat solid tumors, particularly brain cancer in adults and DIPG in children. Trabedersen (OT101) is a new antisense oligodeoxynucleotide (ODN) developed by Oncotelic for the treatment of patients with pancreatic carcinoma, malignant melanoma, colorectal carcinoma, high-grade glioma (HGG), and other TGF-2 overexpressing cancers (e.g., prostate carcinoma, renal cell carcinoma, etc.). TGF- is overexpressed in malignancies, suppressing the host’s innate immune response to the tumors. OT-101 treatment removes the TGF-cloaking effect, allowing innate or therapeutic immunity to target and eradicate tumors. Currently, the drug is in Phase III development for glioblastoma treatment.

Gain more knowledge on emerging glioblastoma drugs @ Glioblastoma Treatment Drugs 

Glioblastoma Pipeline Therapies and Key Companies

  • TVB2640:Ascletis Pharma
  • Trabedersen: Oncotelic Therapeutics
  • Selinexor: Karyopharm Therapeutics
  • Onfekafuspalfa: Philogen
  • AZD1390: AstraZeneca
  • YTX7739: Yumanity Therapeutics

Learn more about the glioblastoma FDA-approved drugs @ Glioblastoma Clinical Trials

Glioblastoma Pipeline Therapeutics Assessment  

  • By Product Type
  1. Monotherapy
  2. Combination Therapy
  • By Stage
  1. Discovery
  2. Pre-Clinical
  3. Phase I
  4. Phase II
  5. Phase III
  6. Pre-registration
  • By Route of Administration
  1. Oral 
  2. Parenteral 
  3. Intravitreal
  4. Subretinal
  5. Topical
  • By Molecule Type
  1. Monoclonal Antibody
  2. Peptides
  3. Polymer
  4. Small Molecule 
  5. Gene Therapy

Scope of the Glioblastoma Report

Coverage: Global

Key Glioblastoma Companies: Array Biopharma (NYSE: ARRY), AstraZeneca (NASDAQ: AZN), Doule bond Pharmaceuticals, Philogen (BIT: PHIL), Immatics N.V (NASDAQ: IMTX), BioNTech (NASDAQ: BNTX), InovioPharma, Noxxon Pharma (EPA: ALNOX), Celgene Corporation, Karyo Pharma (NASDAQ: KPTI), Neugate Theranostics, Novartis (NYSE: NVS), Orphelia Pharma, Merck (NYSE: MRK), Acerta Pharma, Genenta Science (NASDAQ: GNTA), CNS Pharmaceutical (NASDAQ: CNSP), Pfizer (NYSE: PFE), Roche (SWX:ROG), Oncotelic Therapeutics (OTCMKTS: OTLC), Autotelic Therapeutics, ACADIA Pharmaceuticals (NASDAQ: ACAD), Mayo Clinic, Cytogel, Xgene Pharmaceutical, Ascletis (OTCMKTS: ASCLF), 3-V Biosciences, Yumanity Therapeutics (NASDAQ: YMTX), and others

Key Glioblastoma Pipeline Therapies: Onfekafuspalfa, PLX3397, APVAC1, INO5401, Olaptesed pegol, Selinexor, L19TNF, H1PV, NG101m, ACP196, Temferon, Berubicin Hydrochloride, VXM01, Avelumab, Trabedersen, TVB2640, AZD1390, YTX7739, WP1122, and others

Table of Contents

1. Glioblastoma Pipeline Report Introduction
2. Glioblastoma Pipeline Report Executive Summary
3. Glioblastoma Pipeline: Overview
4. Analytical Perspective In-depth Commercial Assessment
5. Glioblastoma Pipeline Therapeutics
6. Glioblastoma Pipeline: Late Stage Products (Pre-registration)
7. Glioblastoma Pipeline: Late Stage Products (Phase III)
8. Glioblastoma Pipeline: Mid Stage Products (Phase II)
9. Glioblastoma Pipeline: Early Stage Products (Phase I)
10. Glioblastoma Pipeline Therapeutic Assessment
11. Inactive Products in the Glioblastoma Pipeline
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Key Companies
14. Key Products in the Glioblastoma Pipeline
15. Unmet Needs
16. Market Drivers and Barriers
17. Future Perspectives and Conclusion
18. Analyst Views
19. Appendix

Got queries? Reach out for more information @ Glioblastoma Drug Pipeline Assessment

Related Reports

Glioblastoma Market

Glioblastoma Market Insights, Epidemiology, and Market Forecast-2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key glioblastoma companies including Orphelia Pharma, Merck, Acerta Pharma, Genenta Science, CNS Pharmaceutical, Pfizer, Roche, among others.

Glioblastoma Epidemiology Forecast

Glioblastoma Epidemiology Forecast to 2032 report delivers an in-depth understanding of the disease, historical and forecasted glioblastoma epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

Recurrent Glioblastoma Market

Recurrent Glioblastoma Market Insights, Epidemiology, and Market Forecast-2032 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key recurrent glioblastoma companies including Genenta Science, CNS Pharmaceutical, Pfizer, Roche, among others.

Glioblastoma Multiforme Market

Glioblastoma Multiforme Market Insights, Epidemiology, and Market Forecast-2030 report deliver an in-depth understanding of the disease, historical and forecasted epidemiology, as well as the market trends, market drivers, market barriers, and key glioblastoma multiforme companies including CNS Pharmaceutical, Pfizer, Roche, Autotelic Therapeutics, among others.

Glioblastoma Multiforme Pipeline

Glioblastoma Multiforme Pipeline Insight, 2022 report provides comprehensive insights about the pipeline landscape, pipeline drug profiles, including clinical and non-clinical stage products, and the key glioblastoma multiforme companies, including CNS Pharmaceutical, Pfizer, Roche, Autotelic Therapeutics, among others.

Recurrent Glioblastoma Epidemiology Forecast

Recurrent Glioblastoma Epidemiology Forecast to 2032 report delivers an in-depth understanding of the disease, historical, and forecasted recurrent glioblastoma epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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About DelveInsight

DelveInsight is a leading Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.  

Contact Us

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info@delveinsight.com 

+1(919)321-6187

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