“๐๐ง ๐ญ๐จ๐๐๐ฒ’๐ฌ ๐๐จ๐ฆ๐ฉ๐๐ญ๐ข๐ญ๐ข๐ฏ๐ ๐ฆ๐๐ซ๐ค๐๐ญ, ๐ข๐ง๐๐ฎ๐ฌ๐ญ๐ซ๐ฒ ๐๐ง๐๐ฅ๐ฒ๐ฌ๐ข๐ฌ ๐ข๐ฌ ๐ ๐๐ซ๐ข๐ญ๐ข๐๐๐ฅ ๐ฌ๐ญ๐๐ฉ ๐ข๐ง ๐ข๐๐๐ง๐ญ๐ข๐๐ฒ๐ข๐ง๐ ๐ญ๐ก๐ ๐๐จ๐ซ๐ซ๐๐๐ญ ๐ญ๐๐ซ๐ ๐๐ญ ๐๐จ๐ง๐ฌ๐ฎ๐ฆ๐๐ซ๐ฌ ๐๐ง๐ ๐ฉ๐ซ๐จ๐ฏ๐ข๐๐ข๐ง๐ ๐๐ฎ๐ฌ๐ญ๐จ๐ฆ๐ข๐ฌ๐๐ ๐ฌ๐จ๐ฅ๐ฎ๐ญ๐ข๐จ๐ง๐ฌ ๐๐จ๐ซ ๐ญ๐ก๐๐ข๐ซ ๐๐ฎ๐ฌ๐ข๐ง๐๐ฌ๐ฌ ๐ง๐๐๐๐ฌ. ๐๐ก๐ข๐ฅ๐ ๐๐จ๐ซ๐ฆ๐ฎ๐ฅ๐๐ญ๐ข๐ง๐ ๐ญ๐ก๐๐ฌ๐ ๐ฌ๐จ๐ฅ๐ฎ๐ญ๐ข๐จ๐ง๐ฌ, ๐๐ฏ๐๐ซ๐ฒ ๐๐๐๐๐ญ ๐๐ง๐ ๐ฌ๐ฉ๐๐๐ข๐๐ข๐ ๐ฉ๐ซ๐จ๐๐ฅ๐๐ฆ ๐ฉ๐ซ๐๐ฌ๐๐ง๐ญ๐๐ ๐๐ฒ ๐ญ๐ก๐ ๐ฉ๐๐ซ๐ญ๐ข๐๐ฎ๐ฅ๐๐ซ ๐ฌ๐๐๐ญ๐จ๐ซ ๐ข๐ฌ ๐ญ๐ก๐จ๐ซ๐จ๐ฎ๐ ๐ก๐ฅ๐ฒ ๐๐จ๐ง๐ฌ๐ข๐๐๐ซ๐๐. ๐๐ญ ๐๐ฅ๐ฌ๐จ ๐๐จ๐ง๐ฌ๐ข๐๐๐ซ๐ฌ ๐ง๐ฎ๐ฆ๐๐ซ๐จ๐ฎ๐ฌ ๐ ๐จ๐ฏ๐๐ซ๐ง๐ฆ๐๐ง๐ญ ๐ซ๐๐๐จ๐ซ๐ฆ๐ฌ, ๐ญ๐ก๐ ๐๐จ๐ฆ๐ฉ๐๐ญ๐ข๐ญ๐ข๐ฏ๐ ๐๐ง๐ฏ๐ข๐ซ๐จ๐ง๐ฆ๐๐ง๐ญ, ๐๐ฎ๐ฌ๐ญ๐จ๐ฆ๐๐ซ ๐๐๐ก๐๐ฏ๐ข๐จ๐ฎ๐ซ, ๐๐ฎ๐ซ๐ซ๐๐ง๐ญ ๐๐ง๐ ๐๐ฎ๐ญ๐ฎ๐ซ๐ ๐๐ฎ๐ฌ๐ข๐ง๐๐ฌ๐ฌ ๐ฌ๐ญ๐ซ๐๐ญ๐๐ ๐ข๐๐ฌ, ๐๐ง๐ ๐ซ๐๐ฉ๐ข๐๐ฅ๐ฒ ๐๐ก๐๐ง๐ ๐ข๐ง๐ ๐ญ๐๐๐ก๐ง๐ข๐๐๐ฅ ๐๐ซ๐๐๐ค๐ญ๐ก๐ซ๐จ๐ฎ๐ ๐ก๐ฌ. ๐๐ง๐๐ฎ๐ฌ๐ญ๐ซ๐ฒ ๐๐ง๐๐ฅ๐ฒ๐ฌ๐ข๐ฌ ๐๐ข๐๐ฌ ๐ข๐ง ๐ญ๐ก๐ ๐๐จ๐ซ๐ฆ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐จ๐ ๐๐ฎ๐ฌ๐ข๐ง๐๐ฌ๐ฌ ๐ฉ๐ฅ๐๐ง๐ฌ ๐๐ง๐ ๐ฉ๐จ๐ฅ๐ข๐๐ข๐๐ฌ.”
There is a vast range of possible causes for circadian rhythm sleep disorder, but it has been associated with certain diseases such as Parkinson’s and Alzheimer’s disease. While no substance is known to trigger this disorder, irregular sleep-wake patterns are caused by individual choices. For instance, a delayed sleep phase may be caused by shift work or jet lag. Environmental factors such as lighting or noise may predispose someone to the disorder.
Treatment options for circadian rhythm sleep disorder vary greatly and depend on the severity of the condition and the patient’s quality of life. This sleep supplement can help re-orient the circadian rhythm and induce sleepiness. It is important to see a physician before using melatonin supplements to treat circadian rhythm sleep disorder.
Insomnia and fatigue are signs of a circadian rhythm sleep disorder. People with this condition may be more likely to commit errors at work, experience increased risk of accidents and suffer from irritability.
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Excessive daytime sleepiness:
The excessive daytime sleepiness can affect the drivers, As per public health, due to sleepiness at wheel (while driving) many road accidents happens. Population who suffers from excessive daytime sleepiness is about 5%.
Increase in sleep-wake disorders:
As per stated by AJMC, (The center for biosimilar), the prevalence of narcolepsy had increased about 14%, from 38.9 in 2013 to 44.3 in 2016. The OSA increased 41% of prevalence from the study period of 2429 to 3240. This increased prevalence was also observed in other examined sleep disorders.
Furthermore, increasing U.S. FDA approval, announcement of new information or manufacturing capabilities and agreements by market players are expected to boost the circadian rhythm sleep disorder market growth over the forecast period.
For instance, Vanda Pharmaceutical, in December 2020 announced that U.S. Food and Drug Administration (FDA) approved its HETLIOZ capsule and liquid formulations for the diagnosis of children and adults, associated with Smith-Magenis Syndrome (SMS) a development disorder which causes sleep disturbances.
Moreover, in October 2018, Eisai announced that they presented new information for phase II evaluation of Lemborexant, an experimental sleep-wake regulation agent, for the diagnosis of irregular sleep wake rhythm disorder in sufferer patient with mild to moderate Alzheimerโs disease. Alzheimer โs disease data was presented in 11thย Clinical Trials conference in Barcelona, Spain. Including insomnia disorder, Lemborexant is also developed for diagnosis of multiple sleep-wake disorders.
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Circadian Rhythm Sleep Disorders Market โ Regional Insights
Among regions, North America and Europe are estimated to account for significant market share in the global circadian rhythm sleep disorders market. This is attributed to rising prevalence of chronic diseases (Obesity, Depression, Cardiovascular disease) and geriatric population. For instance, according to the European Commission, 2013 report, total 17% of European Population was above age 65 years. Therefore, rise in geriatric population is expected to drives growth of the circadian rhythm sleep disorders market in European Region. By National Library of Medicine, most common circadian rhythm sleep disorder is delayed sleep phase disorder with an estimated prevalence of 0.17% in the U.S. population and 7โ16% prevalence among adolescents.
Circadian Rhythm Sleep Disorders Market โ Taxonomy
By Treatment Type:
- Healthy Lifestyle Changes
- Bright Light Therapy
- Melatonin
By Application Type:
- Delayed Sleep Phase Disorder
- Advanced Sleep Phase Disorder
- Jet Lag
- Shift Work Disorder
- Irregular Sleep Wake Rhythm
- Non-24-hour Sleep-wake Syndrome
By Distributionย Channel:
- Institutional Sales
- Retail Sales
By Drugs:
- Melatonin
- Modafinil
- Tasimelteon
By End User:
- Hospitals
- Home Care Settings
- Sleep Centers
By Region:
- North America
- Europe
- Asia Pacific
- Middle East & Africa
- Latin America
Circadian Rhythm Sleep Disorders Market โ Competitive Landscape
Key players operating in the circadian rhythm sleep disorder market include:
- Vanda Pharmaceuticals
- Aeroflow, Inc.
- Cephalon, Inc.
- Takeda Pharmaceutical Company
- Teva Pharmaceutical Industries Ltd.
- Mylan N.V.
- The Sunbox Company
- Verilux, Inc.
- Northern Light Technologies
- Koninklijke Philips N.V.
- Amjo Corp.
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