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Soft Robotic Sleeve for Lymphedema Treatment

May 6th, 2022 Conn Hastings Materials, Oncology, Rehab

Researchers at the University of Waterloo in Canada created a soft robotic sleeve to treat lymphedema. Lymphedema involves fluid accumulation in tissues because of damage to the lymph system. This wearable sleeve combines a microfluidic controller and soft robotic components that apply compression to the arm to reduce and control fluid accumulation. The small components avoid the need for a stationary pump to inflate the sleeve and allow for tetherless use during regular activities.

Lymphedema often strikes breast cancer patients, who frequently require surgical removal of lymph nodes in the armpit. This can cause fluid buildup in the arm, which can swell significantly. At present, compression sleeves can be used to treat the condition, but current iterations of such devices typically require a stationary pump to inflate the sleeve. Such bulky and expensive equipment is impractical to use for extended periods as it requires a user to sit in one place during use.

“My definition of wearable is you can wear it and do whatever you want, and not be plugged into a wall,” said Carolyn Ren, one of the developers of the new system. “Bringing in the microfluidics field, we wanted to make the system battery-powered but without compromising the performance.”

The system employs a microfluidic device that contains a series of channels that offer different degrees of resistance, meaning that air travels through them either quicker or slower. This system creates a time delay that controls the sequential inflation of different balloons within the sleeve so that the wearable sequentially pushes fluid in the tissue up and out of the arm.   

The device contains miniaturized valves and a 3.7-volt lithium-ion battery within a small control unit. The small components means that the system should cost just hundreds of dollars to manufacture, compared with thousands for conventional equipment.

Interestingly, the technology may also have other applications, including as a component in prosthetics for lower leg amputees. If a prosthetic wearer’s leg swells during activity, conventional prosthetic sockets cannot adjust, potentially leading to discomfort and friction. The researchers believe that soft robotics may assist in making the socket more adaptable and comfortable to wear.    

Study in Biomicrofluidics: A novel air microfluidics-enabled soft robotic sleeve: Toward realizing innovative lymphedema treatment

Via: American Institute of Physics

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Conn Hastings

Conn Hastings received a PhD from the Royal College of Surgeons in Ireland for his work in drug delivery, investigating the potential of injectable hydrogels to deliver cells, drugs and nanoparticles in the treatment of cancer and cardiovascular diseases. After achieving his PhD and completing a year of postdoctoral research, Conn pursued a career in academic publishing, before becoming a full-time science writer and editor, combining his experience within the biomedical sciences with his passion for written communication.

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