Oligonucleotide Therapeutics Market 2022
This report provides in depth study of “Oligonucleotide Therapeutics Market” using SWOT analysis i.e. Strength, Weakness, Opportunities and Threat to the organization. Oligonucleotide Therapeutics Market report also provides an in-depth survey of key players in the market which is based on the various objectives of an organization such as profiling, the product outline, the quantity of production, required raw material, and the financial health of the organization.
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Oligonucleotides are short chain RNA or DNA which are usually manufactured by utilizing automated synthesizers. Purification of the oligonucleotide is done by anion exchange chromatography which is followed by desalting and freezing technique. For the synthesis of siRNA duplex oligonucleotide, an annealing step is carried out where two purified oligonucleotide strands are brought together in an equimolar ratio.
Oligonucleotide therapeutics are different from conventional medicine as they can inhibit the expression of certain genes. This has given rise to innovative new oligonucleotides that can target specific genes and treat chronic diseases. The development of oligonucleotide therapeutics is done through chemically modified artificial nucleic acids. The artificial oligonucleotides are being developed which has improved in vivo stability and enhanced affinity to target mRNA.
Oligonucleotide Therapeutics Market: Dynamics
The demand for oligonucleotides is expected to upsurge as there are very few approved molecules. This has offered oligonucleotide market players a wide scope to discover new molecular entities. Moreover, the technology upgrades of chemically synthesized oligonucleotides have led to the development of more stable and extended half-life molecules.
There are around 135 oligonucleotide therapeutics currently in different stages of drug development, which may further add to the limited three approved drugs currently available in the oligonucleotide therapeutics market.
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Oligonucleotide Therapeutics Market: Segmentation
On the basis of application
Infectious diseases
Oncology
Neurodegenerative disorders
Cardiovascular diseases
Kidney diseases
Others
On the basis of type
Antisense
Ribozymes
Aptamers
miRNA
CpG/Immunostimulatory
RNAi
Oligonucleotide Therapeutics Market: Region-wise Outlook
The presence of the main market leaders, market consolidation and commercialization of new molecules are all contributing towards the dominating position of North America in the oligonucleotides therapeutic market. Miragen Therapeutics, Inc. agreed to merge with Signal Genetics, Inc for an initial investment of USD 40 million. Through this merger both the companies expect to develop micro RNA-targeted oligonucleotide clinical products.
New molecule application is also another strategy the market players are using to mark their presence in the oligonucleotide therapeutic market. Biogen recently received FDA approval for a new drug application for nusinersen. If approved, the antisense oligonucleotides molecule would be the first of its kind to be used for treating spinal muscular atrophy.
Asia-Pacific is the fastest growing region as several oligonucleotide therapeutics manufacturers are looking forward to establishing manufacturing facilities in this region. Moreover, research undertaking and funding in the synthesis of oligonucleotides are expected to add on to the increasing demand.
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Recently, Daiichi Sankyo Co., Ltd. announced its intention to open up a new company named Orphan Disease Treatment Institute Co., Ltd. to treat Duchenne muscular dystrophy through its active ingredient ENA oligonucleotide. The company is a collaboration between Daiichi, Mitsubishi UFJ Capital Co., Ltd. and Innovation Network Corporation of Japan and looks forward to entering the oligonucleotide therapeutics market.
Key Questions Answered in the Oligonucleotide Therapeutics Market Report
How is the Oligonucleotide Therapeutics Market expected to grow over the projected period?
What direction is the Oligonucleotide Therapeutics Market expected to take in terms of volume and value during the forecast period?
What is the impact of macroeconomic factors on the Oligonucleotide Therapeutics Market in future?
What are the key market drivers in the Oligonucleotide Therapeutics Market?
What are significant opportunities and improvement areas for Oligonucleotide Therapeutics Market manufacturers?
What are the key developments and trends taking over the Oligonucleotide Therapeutics Market?
Which are the emerging countries that are expected to create significant growth opportunities in the Oligonucleotide Therapeutics Market?
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