Carglumic acid is a drug used to treat hyperammonemia in patients with a deficiency in N-acetyl glutamate synthase. Hyperammonemia is a rare genetic disorder (a metabolic condition) characterized by elevated levels of ammonia in the blood. Increased levels of ammonia are a primary cause of neurological disorders, such as Reye’s syndrome, hepatic encephalopathy, congenital deficiencies of urea cycle enzymes, some toxic encephalopathy, and several other metabolic disorders.
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Rise in research and development (R&D) activities is expected to boost the growth of the global carglumic acid market during the forecast period. For instance, in April 2017, Dipharma S.A. announced the successful development of a new, fast dissolving formulation of carglumic acid tablets stable at room temperature. Carglumic acid is a key therapeutic tool for the management of life threatening, rare metabolic disorders.
Moreover, frequent approvals and launches of novel products is expected to propel the growth of the global carglumic acid market over the forecast period. For instance, in September 2015, Health Canada has granted marketing authorization for Carbaglu (carglumic acid) from Italian pharma company Recordati. Carbaglu (carglumic acid) has been approved for the treatment of acute hyperammonemia or chronic hyperammonemia.
Side effects associated with carglumic acid and high cost of drugs (tablets) is expected to hinder growth of the global carglumic acid market. For instance, the drug, named Carbaglu (carglumic acid), costs around US$ 1042.12 for 5 tablets.
Moreover, such as carglumic acid can cause serious side effects such as anemia, ear infection, anorexia, asthenia, hyperhidrosis, influenza, pneumonia, and somnolence.
North America is expected to witness robust growth in the global carglumic acid market due to the increasing prevalence of neurological disorders and metabolic disorders and increasing demand for carglumic acid (a class of drug) in the region. For instance, in April 2017, Recordati establishes Canadian presence with launch of Recordati Rare Diseases Canada Inc., will be the exclusive provider of several treatments, including Carbaglu, Cosmegen (dactinomycin),and Cystadane (betaine anhydrous) in Canada.
Moreover, Asia Pacific is expected to witness significant growth in the global carglumic acid market due to favorable government initiatives and well-established healthcare infrastructure. For instance, in February 2019, establishment of National Network to Collaborate on Diagnosis and Treatment of Rare Diseases was announced by the National the Health Commission of the People’s Republic of China to further combat rare diseases, such as hyperammonemia.
Major players active in the global carglumic acid market are Dipharma Francis S.r.l., Recoedati S.p.A, Civentichem LLC., and Manus Aktteva Biopharma LLP., among others.
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Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Carglumic Acid Market Size Analysis from 2021 to 2028
11.6 COVID-19 Outbreak: Carglumic Acid Industry Impact
Chapter 2 Global Carglumic Acid Competition by Types, Applications, and Top Regions and Countries
2.1 Global Carglumic Acid (Volume and Value) by Type
2.3 Global Carglumic Acid (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Carglumic Acid Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Carglumic Acid Market Analysis
Chapter 6 East Asia Carglumic Acid Market Analysis
Chapter 7 Europe Carglumic Acid Market Analysis
Chapter 8 South Asia Carglumic Acid Market Analysis
Chapter 9 Southeast Asia Carglumic Acid Market Analysis
Chapter 10 Middle East Carglumic Acid Market Analysis
Chapter 11 Africa Carglumic Acid Market Analysis
Chapter 12 Oceania Carglumic Acid Market Analysis
Chapter 13 South America Carglumic Acid Market Analysis
Chapter 14 Company Profiles and Key Figures in Carglumic Acid Business
Chapter 15 Global Carglumic Acid Market Forecast (2021-2027)
Chapter 16 Conclusions
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