Market- Overview
The Global Bisphosphonates Market is estimated to reach US$ XX million during the forecast period (2022-2029).
Bisphosphonates are drugs that strengthen bones by slowing or preventing bone loss. Bisphosphonates work by preventing osteoclasts from breaking down and reabsorbing minerals like calcium from bone (the process is known as bone resorption). Bisphosphonates improve bone mass by allowing osteoblasts (bone-building cells) to act more effectively. Bisphosphonates are used to treat osteoporosis and Paget’s disease of the bones and lower elevated calcium levels in cancer patients.
Market Dynamics
The global bisphosphonates market growth is driven by the growing geriatric population, increasing number of women in the post-menopausal stage, and increasing prevalence of the bone disease.
An increasing number of women in the post-menopausal stage will drive the market growth
According to the United Nations, 985 million women aged 50 and up in the world.By 2050, the figure is expected to rise to 1.65 billion.” “An estimated 6,000 women in the United States reach menopause every day (more than 2 million per year).” “By 2026, it is estimated that nearly one-quarter (22%) of the Canadian population will be made up of women over the age of 50.” (Source: National Academy of Medical Sciences). It is estimated that around 13 million women in the UK are currently peri or menopausal (Wellbeing of Women) – that is one-third of the entire UK female population.” Osteoporosis, which is more common in older postmenopausal women, raises the risk of fractures, which can result in significant morbidity and mortality. Osteoporosis is primarily caused by postmenopausal bone loss due to oestrogen deficiency. Advanced age, genetics, smoking, thinness, and a variety of diseases and drugs that impair bone health are all important risk factors for postmenopausal osteoporosis.
Furthermore, the proportion of the world’s population aged 60 and up will nearly double from 12 percent to 22 percent between 2015 and 2050.By 2023, the number of persons aged 60 and more will outweigh youngsters under five.By 2050, 80% of the world’s elderly will live in low- and middle-income countries.The population is aging at a considerably higher rate than in the past.(Source:World Health Organization), this population will more likely to be suffered by bone disorders thus increasing the demand for Bisphosphonates.
These factors, as mentioned above, have a significant impact on the Bisphosphonates industry.
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Market Segmentation
By Therapeutic Areas
- Cancer
- Myeloma
- Breast Cancer
- Degenerative Bone Diseases
By Drugs
- Risedronate(Actonel)
- Alendronate(Fosamax)
- Ibandronate(Boniva)
By Mode of Delivery
- Oral
- Intravenous
Competitive Landscape
The global market for bisphosphonates is moderately competitive, with several major players. Merck & Co Inc, Sanofi- Aventis, F.Hoffmann-La Roche Ltd, Novartis International AG, Procter & Gamble Company, Pfizer Inc, Teva Pharmaceuticals Industries Ltd, Apotex Inc, Genentech Inc are among the market’s major players. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the Bisphosphonates market globally. For instance, on Februray 19 2019, ZIRABEVTM (bevacizumab), a biosimilar to Avastin®, has been approved in Europe by Pfizer.
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