Hypocretin or Orexin is a neuropeptide produced by the lateral hypothalamus that regulates arousal, appetite, wakefulness, and other habits. Orexin receptor antagonists are drugs used to treat insomnia.
Suvorexant is a double orexin receptor antagonist that deterrents both OX1R and OX2R pathways. It promotes sleep through the mandatory obstruction of orexin-A and orexin-B, neuropeptides that promote awakening. The human brain contains around 70,000 Orexin neurons, apprear in the peripheral lateral hypothalamus, that send signals via the brain and spinal cord.
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Global Orexin Receptors Antagonist Market: Drivers
The key driver of the global orexin receptors antagonist market is the increasing cases of insomnia. It is caused by a number of factors, including depression, stress and anxiety. Lifestyle problems can lead to insomnia such as irregular sleep patterns, drinking and smoking before going to bed. Insomnia is caused by the growing aging population, increasing stress in the urban population. As per the American Academy of Sleep Medicine AASM reported in 2014, insomnia affects 30% of adults, 15-20% of people have short-term insomnia and 10% of adults have severe insomnia, around the world.
Increasing acknowledgement about insomnia and entry into the Belsomara market is likely to increase the growth of the global ORA market. Furthermore, researches are being conducted on whether suvorexant can be utilized to treat depression and anxiety so as to further increase the global ORA market.
Global Orexin Receptors Antagonist Market: Restraints
Although the best drug available against insomnia is suvorexant (Orexin Receptors Antagonist), other classes of drugs like Melatonin Antagonist, Antidepressants, Non-benzodiazepines and Benzodiazepines, medical devices like SR1 Delta Sleeper, Fisher Wallace Stimulator, Dream Headband, Sleep Shepherd Blue, 2Breathe Sleep Inducer can also help to treat insomnia which can negatively obstruct the market growth.
Furthermore, in 2010 the National Sleep Foundation (NSF) states that only 15% of people were diagnosed with insomnia and only 6% received treatment. The general disregard for the side effects of the drug, such as insomnia and headaches, insomnia, drowsiness the next day, and weight loss, prevents patients from using the drug.
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Furthermore, a clinical study by NCBI in 2015 showed that placebo therapy for insomnia is also efficient for patients who are hindering the growth of the global ORA market.
Global Orexin Receptors Antagonist Market: Regional analysis
North America leads the orexin receptors antagonist market. The growing demand and awareness of insomnia treatments in the US and Canada and the high healthcare costs are likely to drive the market growth. Furthermore, the high rate of insomnia within the elderly in the US is likely to increase demand. In 2017, 30-50% of the US population over the age of 60 had insomnia, as per AASM.
In the Asia-Pacific, China is likely to see a lucrative market growth due to the high population of insomnia. As per the China National Knowledge Internship (CNKI), 15% of China’s population aged 43 years and over suffers from insomnia in 2017, as per a report in the Journal of Community Medicine and Health Education. Significant growth is likely in Asia Pacific in the near future as shift-work disease and increasing stress levels are likely to increase the rate of patients in Asia Pacific. Additionally, favourable compensation strategies for treatment products, a strong production pipeline and rising stress levels are other factors contributing to the increase.
Global Orexin Receptors Antagonist Market: Segmentation
On the basis of Application, Global Orexin Receptors Antagonist Market is segmented into:
- Depression and Anxiety
On the basis of Dosage, Global Orexin Receptors Antagonist Market is segmented into:
On the basis of Region, Global Orexin Receptors Antagonist Market is segmented into:
- North America
- Asia Pacific
- Latin America
- Middle East
𝗕𝘂𝘆 𝗡𝗼𝘄 𝗧𝗼 𝗚𝗲𝘁 𝗙𝗹𝗮𝘁 30% 𝗢𝗳𝗳
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Merck & Co. Inc., Sanofi, Pfizer, Inc., Takeda Pharmaceutical Company Ltd., Purdue Pharmaceuticals L.P., Eisai, Co. Ltd., Meda Consumer Healthcare Inc., Pernix Therapeutics, Vanda Pharmaceuticals, and ECR Pharmaceuticals.
Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Global Orexin Receptors (Hypocretin Receptor) Antagonist Market Size Analysis from 2021 to 2027
11.6 COVID-19 Outbreak: Orexin Receptors (Hypocretin Receptor) Antagonist Industry Impact
Chapter 2 Global Orexin Receptors (Hypocretin Receptor) Antagonist Competition by Types, Applications, and Top Regions and Countries
2.1 Global Orexin Receptors (Hypocretin Receptor) Antagonist (Volume and Value) by Type
2.3 Global Orexin Receptors (Hypocretin Receptor) Antagonist (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Orexin Receptors (Hypocretin Receptor) Antagonist Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 6 East Asia Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 7 Europe Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 8 South Asia Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 9 Southeast Asia Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 10 Middle East Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 11 Africa Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 12 Oceania Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 13 South America Orexin Receptors (Hypocretin Receptor) Antagonist Market Analysis
Chapter 14 Company Profiles and Key Figures in Orexin Receptors (Hypocretin Receptor) Antagonist Business
Chapter 15 Global Orexin Receptors (Hypocretin Receptor) Antagonist Market Forecast (2021-2027)
Chapter 16 Conclusions
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