Protein A Resin Market
Market Overview
Protein A is a 42-kDa chemical component found in the cell wall of staphylococcu aureus and widely used in various applications across biotechnological industry. This is mainly attributed to features such as its ability to bind all human IgG class immunoglobulins except IgG3.
Statistics:
The global protein A resin market is estimated to account for US$ 511.7 Mn in terms of value in 2020 and is expected to reach US$ 907.3 Mn by the end of 2027.
Market Drivers
Rising approval of monoclonal antibodies for the treatment of different disease is expected to drive growth of the global protein A resin market during the forecast period. For instance, in December 2019, The World Health Organization (WHO) prequalified its first biosimilar medicine – trastuzumab –– a monoclonal antibody for the treatment of early stage breast cancer. On an average trastuzumab costs US$ 20,000. However, the biosimilar version of trastuzumab is generally 65% cheaper than the originator.
Furthermore, growing cases of chronic diseases such as cardiovascular disease and cancer is expected to propel the global protein A resin market growth over the forecast period. According to the American Cancer Society, in 2019, there will be an estimated 1,762,450 new cancer cases diagnosed and 606,880 cancer deaths in the U.S.
𝐂𝐡𝐫𝐢𝐬𝐭𝐦𝐚𝐬 𝐒𝐚𝐥𝐞 𝐈𝐬 𝐋𝐢𝐯𝐞!
𝐁𝐮𝐲 𝐍𝐨𝐰 𝐓𝐨 𝐀𝐯𝐚𝐢𝐥 𝐃𝐢𝐬𝐜𝐨𝐮𝐧𝐭 𝐅𝐫𝐨𝐦 𝟐𝟓-𝟑𝟎% 𝐭𝐢𝐥𝐥 𝟑𝟏-𝐃𝐞𝐜-𝟐𝟎𝟐𝟏
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Statistics:
Natural Protein A held dominant position in the global protein A resin market in 2019, accounting for 63.1% share in terms of value, followed by Recombinant Protein A, respectively.
Market Restraint
Availability of substitute methods for purification of monoclonal antibodies is expected to restrain growth of the global protein A resin market during the forecast period. Affinity chromatography, which utilizes protein A resin, is a conventional method for purification of monoclonal antibodies. However, cost and availability of protein A resin is very high to perform purification process. To reduce production costs, various companies prefer alternative methods such as membrane chromatography, mixed chromatography, and aqueous two-phase extractions (ATPS) for purification of monoclonal antibodies in large scales.
Furthermore, high cost related to protein A resin is expected to hamper the global protein A resin market growth over the forecast period. The cost of protein A resin is US$ 15,000 – US$ 16,000 per one litre. Large-scale manufacturers require protein A in large amounts for purification, which increases production costs of monoclonal antibodies.
Market Opportunities
Frequent launch of monoclonal antibodies can present lucrative growth opportunities in the market. For instance, in September 2019, Biocare Medical, LLC launched a new mouse monoclonal antibody, p16 INK4a, for in vitro diagnostic use in the qualitative identification of the p16 INK4a protein by immunohistochemistry in formalin-fixed paraffin-embedded human tissues.
Moreover, rising investment in R&D in monoclonal antibodies can provide major business opportunities. For instance, in February 2018, Ferring Pharmaceuticals announced to invest around US$ 30 million in the new Ferring Biotech Center in Saint-Prex, Switzerland, for R&D in monoclonal antibodies and biologics manufacturing.
The global protein A resin market was valued at US$ 474.0 Mn in 2019 and is forecast to reach a value of US$ 907.3 Mn by 2027 at a CAGR of 8.5% between 2020 and 2027.
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Market Trends
Rising research and development activities in synthesis of protein is one of the emerging trends in the market. For instance, in May 2020, researchers from Massachusetts Institute of Technology reported developed a protocol to rapidly produce protein chains up to 164 amino acids long.
Furthermore, key companies are focused on product launches, in order to gain a competitive edge in the market. For instance, in June 2018, Purolite Life Sciences, a provider of pharmaceutical applications, launched new-generation protein A agarose resin ‘Praesto Jetted A50’. This new resin is a combination of jetting technology and high performance protein A ligand.
Competitive Section
Major players operating in the global protein A resin market include, GE Healthcare, Thermo Fisher Scientific, Repligen, Tosoh Bioscience, EMD Millipore, Novasep, GenScript Biotech Corporation, Purolite Life Sciences, and Expedeon Ltd.
Key Developments
Major players in the global protein A resin market are focused on investment in expansion of manufacturing capabilities to enhance their market share. For instance, in September 2018, Purolite Life Sciences started a manufacturing facility in Llantrisant Business Park, Wales, capable of producing 100,000L of its Praesto range of agarose Protein A affinity resins.
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Table of Contents
- Research Objective and Assumption
- Research Objectives
- Assumptions
- Abbreviations
- Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Market Snippet, By Product
- Market Snippet, By Matrix Type
- Market Snippet, By Application
- Market Snippet, By End User
- Coherent Opportunity Map (COM)
- Report Description
- Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Drivers
- Restraints
- Market Opportunities
- Impact Analysis
- Key Developments
- Regulatory Scenario
- PEST Analysis
- COVID-19 Impact Analysis
- Market Dynamics
- Global Protein A Resin Market, By Product, 2019 – 2027 (US$ Mn)
- Introduction
- Market Share Analysis, 2019 and 2027 (%)
- Y-o-Y Growth Analysis, 2017–2027
- Segment Trends
- Natural Protein A
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Segment Trends
- Recombinant Protein A
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Segment Trends
- Introduction
- Global Protein A Resin Market, By Matrix Type, 2019 – 2027 (US$ Mn)
- Introduction
- Market Share Analysis, 2019 and 2027 (%)
- Y-o-Y Growth Analysis, 2017–2027
- Segment Trends
- Agarose-based
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Glass or Silica Based
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Organic Polymer Based
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Introduction
- Global Protein A Resin Market, By Application, 2019 – 2027 (US$ Mn)
- Introduction
- Market Share Analysis, 2019 and 2027 (%)
- Y-o-Y Growth Analysis, 2017–2027
- Segment Trends
- Immunoprecipitation (IP)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Antibody Purification
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Introduction
- Global Protein A Resin Market, By End User, 2019 – 2027 (US$ Mn)
- Introduction
- Market Share Analysis, 2019 and 2027 (%)
- Y-o-Y Growth Analysis, 2017–2027
- Segment Trends
- Biopharmaceutical Manufacturers
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Clinical Research Laboratories
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Academic Institutes
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2027, (US$ Mn)
- Introduction
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