Immuno-stimulants, also known as immuno-stimulators, are substances (drugs and nutrients) that stimulate the immune system by inducing activation or increasing the activity of any of its components. Immune-stimulants are of two types, such as specific and non-specific immune-stimulants. Specific immuno-stimulants or immuno-stimulators provide antigenic specificity in immune response, whereas non-specific act irrespective of antigenic specificity to enhance immune response of other antigens or stimulate components. Immune check activators increase the activity of the immune system. However, there are no approved immune check activators available on the market, with more than 20 molecules under clinical trials.
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Cancer immunotherapy specifically target the immune system to trigger a response to destroy tumor cells. Cancer immunotherapy (immuno-oncology) is the artificial stimulation of immune system to treat cancer, improving on the immune system’s natural ability to fight the disease. Various diverse approaches are in use and some are undergoing research and testing. Moreover, randomized trials result in exceptional survival rates and reduced recurrence. When cell-based immunotherapy is used in combination with conservative treatment approaches, the efficacy is improved by around 20–30%. Immunotherapy is treatment that uses certain parts of a person’s immune system to fight diseases such as cancer.
Market players are engaged in research and development activities and focusing on launching new products in the market, which in turn is expected to propel growth of the global immune check activators market over the forecast period. For instance, there are three different DNA immune activators in pre-clinical and clinical studies of Inovio Pharmaceutical. Inovio’s DNA-based IL-12 immune activator enhanced antigen-specific T cell immune responses from its HIV DNA vaccine, named PENNVAX. Moreover, the company has developed a new DNA-based cytokine immune activator, interleukin -33 (IL-33). Thus, frequent approvals and launch are expected to aid in the growth of the market.
Major players are constantly working on research and development, driving the growth of the global immune check activators market. For instance, there are more than 20 pipeline drugs around the world that are used to activate the immune response to antigens. The launch of these molecules, offering a new ray of hope for the treatment of this disease, will greatly accelerate the growth of the immune check activators market.
The global immune check activators market is divided into six regions, such as North America, South America, Asia Pacific, Europe, Middle East, and Africa.
Among regions, North America is expected to substantial robust growth in the global immune check activators market, owing to the increasing prevalence of cancer, increasing adoption of advanced research technologies, increase in government funding and support towards clinical trials, and the presence of major players, especially in the United States and Canada.
For instance, as of 2012, the National Cancer Institute and U.S. Department of Human Health and Services raised around US$ 5.1 billion in funding to develop cancer drugs.
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Key players active in the global immune check activators market are Enumeral, Eutilex Co. Ltd, Genmab, Inovio Pharmaceuticals, Inc., Celldex Therapeutics, ImmuNext, Hoffmann-La Roche, GlaxoSmithKline Pharmaceuticals, Bristol-Myers Squibb, Genentech, and Checkpoint Therapeutics, Inc., among others.
In April 2019, a research team from Medical University of Lublin assessed factors that impact the efficacy of immunotherapy with anti-PD-L1 antibodies in patients with non-small cell lung cancer. According to the team, additional markers are required to accurately determine which patients would benefit from immunotherapy treatment.
In July 2019, a research team from Medical College of Wisconsin conducted a study to identify the roles of Activator Protein (AP)-1 in the regulation of anti-tumor immune responses.
In August 2019, a research team from University of Bourgogne Franche-Comté highlighted the uncertain effects of signal transducer and activator of transcription 3 (STAT3) on the anti-tumoral immune response.
𝐂𝐡𝐫𝐢𝐬𝐭𝐦𝐚𝐬 𝐒𝐚𝐥𝐞 𝐈𝐬 𝐋𝐢𝐯𝐞
𝐁𝐮𝐲 𝐍𝐨𝐰 𝐓𝐎 𝐀𝐯𝐚𝐢𝐥 𝐃𝐢𝐬𝐜𝐨𝐮𝐧𝐭 𝐅𝐫𝐨𝐦 𝟐𝟓-𝟑𝟎% 𝐓𝐢𝐥𝐥 𝟑𝟏-𝐃𝐞𝐜-𝟐𝟎𝟐𝟏
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Table of Content
Chapter 1 Industry Overview
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Immune Check Activators Market Size Analysis from 2021 to 2028
11.6 COVID-19 Outbreak: Immune Check Activators Industry Impact
Chapter 2 Immune Check Activators Competition by Types, Applications, and Top Regions and Countries
2.1 Immune Check Activators (Volume and Value) by Type
2.3 Immune Check Activators (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Immune Check Activators Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Immune Check Activators Market Analysis
Chapter 6 East Asia Immune Check Activators Market Analysis
Chapter 7 Europe Immune Check Activators Market Analysis
Chapter 8 South Asia Immune Check Activators Market Analysis
Chapter 9 Southeast Asia Immune Check Activators Market Analysis
Chapter 10 Middle East Immune Check Activators Market Analysis
Chapter 11 Africa Immune Check Activators Market Analysis
Chapter 12 Oceania Immune Check Activators Market Analysis
Chapter 13 South America Immune Check Activators Market Analysis
Chapter 14 Company Profiles and Key Figures in Immune Check Activators Business
Chapter 15 Immune Check Activators Market Forecast (2021-2028)
Chapter 16 Conclusions
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