Avascular Necrosis Market is expected to witness a CAGR of 6.0% And estimated to surpass US$ 840 Million by 2028 | Bone Therapeutics, Boehringer Ingelheim GmbH, Bayer AG, Enzo Biochem Inc.

The Global Avascular Necrosis Market, accounted for US$ 512.9 million in 2017, and is expected to witness a CAGR of 6.0% over the forecast period (2018 – 2026).

Avascular necrosis is the condition, which is caused when flow of blood towards the thighbone’s head is stopped or reduced, leading to cell death of the bone tissue. No familiar pharmaceutical cure is available for the avascular necrosis’ permanent cure. Several non-operative treatment combinations are used for reducing symptomatic pain including electrical stimulation, shock wave therapy, hyperbaric oxygen therapy, pharmaceuticals (including bisphosphonates, anticoagulants, lipid lowering agents, and vasodilators), and physiotherapy, along with exercises of muscle strengthening.

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There different operative treatments available for avascular necrosis including cartilage and bone grafting, total hip replacement surgery, and osteotomies. Biopsy is the conclusive way of diagnosing avascular necrosis; however, it is used rarely as it needs surgery. Rehabilitation and recovery of avascular necrosis depends upon the used surgical treatment. For instance, usually core decompression needs patients to utilize crutches for couple of weeks, whereas bone graft combined with decompression needs recovery period that is way longer. Osteotomies restricts activity for a couple of months, but, a total hip replacement enables patients to start walking with help of support, in just days.

For delaying the progression of disease as well as reducing the requirement for invasive procedures, early treatment diagnosis plays a crucial part. As per the 2015 study by Chinese Medical Journal, direct price for patients undergo primary total hip arthroplasty for each hip with no revision, in China, is from US$ 8000 to US$ 10,000. Companies in the global avascular necrosis market focus majorly on developing inexpensive and effective therapies to treat the condition. For instance, Enzo Biochem, Inc. and Bone Therapeutics focuses upon gene regulation and treatment of cell-based product, which is expected to surge the market revenue of avascular necrosis.

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Key Takeaways of the Avascular Necrosis Market:

• The global avascular necrosis market is expected to expand at a 6.0% CAGR over the forecast period (2018–2026), due to avascular necrosis’ high prevalence combined with new therapy developments for the treatment of the disease. As per the 2015 data, by National Organization for Rare Disorders, avascular necrosis is amongst the rare disorders which affects 1 out of 2000 individuals.
• Among regions, Asia Pacific is expected to hold dominant position in the global avascular necrosis market growth during the forecast period, due to high rate of incidence of femoral head non-traumatic avascular necrosis. As per the 2010 study by Clinical Orthopedics and Related Research, in Japan around 2500–3300 latest non-traumatic avascular necrosis’ cases of femoral head were registered every year, while over 11,400 patients in 2004 were observed of having sought treatment.
• Major players functioning in the global avascular necrosis market are Bone Therapeutics, Bayer AG, Boehringer Ingelheim GmbH, Enzo Biochem Inc., Eli Lilly and Company, Ethicon Inc., Grifols SA, K-Stemcell Co Ltd., Integra LifeSciences Corporation, Medtronic Plc, Pfizer Inc., Merck KGaA, Sanofi SA, Wright Medical Group N.V., Stryker Corporation, and Zimmer Biomet Holdings.

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Table of Contents

1. Research Objective and Assumption
   • Research Objectives
   • Assumptions
   • Abbreviations
2. Market Overview
   • Report Description
     • Market Definition and Scope
   • Executive Summary
     • Market Snippet, By Type
     • Market Snippet, By Treatment
     • Market Snippet, By Region
   • Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
   • Market Dynamics
     • Drivers
     • Restraints
     • Market Opportunities
   • Impact Analysis
   • Market Trends
   • Key Developments
   • Technological Advancements
   • Epidemiology Analysis
   • PEST Analysis
   • Pipeline Analysis
4. Global Avascular Necrosis Market, By Type, 2016 – 2026, (US$ Million)
   • Introduction
     • Market Share Analysis, 2018 and 2026 (%)
     • Y-o-Y Growth Analysis, 2016 – 2026
     • Segment Trends
   • Trauma  Related  Avascular  Necrosis
     • Introduction
     • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
   • Non-Trauma  Related  Avascular  Necrosis
     • Introduction
     • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
5. Global Avascular Necrosis Market, By Treatment, 2016 – 2026, (US$ Million)
   • Introduction
     • Market Share Analysis, 2018 and 2026 (%)
     • Y-o-Y Growth Analysis, 2016 – 2026
     • Segment Trends
   • Drug-Based
     •  Introduction
     • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
   • Surgery-Based
     • Introduction
     • Market Size and Forecast, and Y-o-Y Growth, 2016 – 2026, (US$ Million)
       • Core decompression surgery
       • Osteotomy
       • Bone graft
       • Total joint replacement
6. Global Avascular Necrosis Market, By Region, 2016 – 2026, (US$ Million)
   • Introduction
     • Market Share Analysis, By Region, 2018 and 2026 (%)
     • Y-o-Y Growth Analysis, By Region, 2016 – 2026
     • Regional Trends
   • North America
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • U.S.
       • Canada
   • Europe
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • U.K.
       • Germany
       • Italy
       • France
       • Spain
       • Russia
       • Rest of Europe
   • Asia Pacific
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • China
       • Japan
       • India
       • ASEAN
       • Australia
       • South Korea
       • Rest of Asia Pacific
   • Latin America
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • Brazil
       • Mexico
       • Argentina
       • Rest of Latin America
   • Africa
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • Northern Africa
       • Central Africa
       • South Africa
   • Middle East
     • Market Size and Forecast, By Type, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Treatment, 2016 – 2026, (US$ Million)
     • Market Size and Forecast, By Country, 2016 – 2026, (US$ Million)
       • GCC Countries
       • Israel
       • Rest of Middle East

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