Overview:
Active Pharmaceutical Ingredients (API) are ingredients used in a pharmaceutical drug of pesticide that is biologically active. These ingredients can be natural substances or chemical or a combination of substances used in a completed pharmaceutical products (FPP) developed for furnishing pharmacological activity or to have a direct effect in the diagnostics, mitigation, cure, prevention or treatment of disease or to have a direct effect in correcting, restoring or modifying physiological functions in humans. API production procedure involves a chain of operations resulting in the preparation of active pharmaceutical ingredients. Fermentation, multi-step chemical synthesis, crystallization, purification, million, drying, labelling, packing and testing are key steps or operations in the active pharmaceutical ingredients process.
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The global active pharmaceutical ingredients market is estimated to be valued at US$ 180.4 billion in 2020 and is expected to exhibit a CAGR of 6.7% during the forecast period (2020-2027).
Impact of COVID-19:
The COVID-19 pandemic has significantly affected active pharmaceutical ingredient market in Asia Pacific, as most of the manufacturers of the ingredients are based in countries like China and India. For instance, according to the U.S. FDA, 230 API manufacturing companies in China which is 13% of overall supply chain, fulfil the demand of API in the U.S. biopharmaceutical facilities, 510 in the U.S. and remaining 1,048 that is 59% other countries. Countries that were severely hit by COVID-19 experienced extreme shortage of raw material and medical resources at manufacturing sites leading to global supply disruption.
Drivers:
Increasing cases of chronic diseases are expected to propel growth of the global active pharmaceutical ingredients market over the forecast period. For instance, in 2015, the World Health Organization estimated global health and mortality rate, where stroke, ischemic heart disease, lower respiratory infection and chronic obstructive lung diseases caused the maximum number of deaths in the last decade.
Moreover, increasing investment in R&D to expand their product line is also expected to boost growth of the global active pharmaceutical ingredients market. For instance, in October 2017, Piramal Pharma Solutions (PPS) made an investment of US$ 55 million in its sites in Asia to increase it capacities and capabilities of API manufacturing.
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Key players are focusing on regional expansion to keep a strong competition in the market, which is expected to fuel growth of the active pharmaceutical ingredients market over the forecast period. For instance, in May 2019, SINOPEC and BASF began manufacturing in propionic acid plant at Verbund site in China having 30,000 metric tons yearly production capacity of propionic acid.
Restraint:
Strict global regulatory policies on facility certification, quality assessment of API manufacturing, growing issues of supply chain security and improved cGMP regulations impacting final cost of active pharmaceutical ingredients products are expected to hamper growth of the global active pharmaceutical ingredients market.
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Major Players:
Key players active in the global active pharmaceutical ingredients market include Pfizer, Inc., Dr. Reddy’s Laboratories Ltd., Mylan N.V., Lonza Group, Fresenius Kabi, Hikma Pharmaceuticals, Apotex Inc., Taro Pharmaceutical Industries Ltd., CordenPharma International, Glenmark Pharma, Teva Pharmaceutical Industries Ltd., Endo International plc, Novartis AG, Amneal Pharmaceuticals LLC, Lupin Limited, Stada Arzneimittel AG, Aurobindo Pharma Limited, Cipla Limited, Biological E. Limited, Evonik Industries AG, Sun Pharmaceutical Industries Ltd., and Krka Pharmaceuticals.
Table of Content
1. Research Objective and assumption
o Research Objectives
o Assumptions
o Abbreviations
2. Market Overview
o Report Description
• Market Definition and Scope
o Executive Summary
• Market Snippet By Product Type
• Market Snippet By Application
• Market Snippet By Technology
• Market Snippet By End User
• Market Snippet By Region
o Coherent Opportunity Map (COM)
3. Market Dynamics, Regulations, and Trends Analysis
o Market Dynamics
• Drivers
• Restraints
• Market Opportunities
o Technological Trends
o PEST Analysis
o Impact Analysis
4. Global Active Pharmaceutical Ingredients Market, By Product Type, 2021 – 2028 (US$ Million)
o Introduction
• Market Share Analysis, 2016 and 2028 (%)
• Y-o-Y Growth Analysis, 2021 – 2028
• Segment Trends
o Reagents & Consumables
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Software’s
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Instruments
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
5. Global Active Pharmaceutical Ingredients Market, By Application, 2021 – 2028 (US$ Million)
o Introduction
• Market Share Analysis, 2016 and 2028 (%)
• Y-o-Y Growth Analysis, 2021 – 2028
• Segment Trends
o Genomics
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Proteomics
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Diagnostics
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Drug Discovery
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
6. Global Active Pharmaceutical Ingredients Market, By Technology, 2021 – 2028 (US$ Million)
o Introduction
• Market Share Analysis, 2016 and 2028 (%)
• Y-o-Y Growth Analysis, 2021 – 2028
• Segment Trends
o Microarrays
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Microfluidics
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
7. Global Active Pharmaceutical Ingredients Market, By End User, 2021 – 2028 (US$ Million)
o Introduction
• Market Share Analysis, 2016 and 2028 (%)
• Y-o-Y Growth Analysis, 2021 – 2028
• Segment Trends
o Hospitals
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Diagnostic Labs
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Academic & Research Institutes
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
o Biotechnology & Pharmaceutical Companies
• Introduction
• Market Size and Forecast, and Y-o-Y Growth, 2021 – 2028, (US$ Million)
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