Ubiquitin enzymes are also known as E2 enzymes found in tissues of a eukaryotic organism and it helps in achieving the second successive step in the ubiquitination process that aims at a protein to cut into various segments through the proteasome.
Globally, there are numerous studies and research groups that are going on for developing a viable drug by using Ubiquitin enzymes market. Many literatures studies in a short span of 1 year, nearly 1500 journals related to ubiquitin enzymes are being published since 2015. A number of procedural advances in ubiquitin enzyme had led to the enhancement and development of varied technological platforms, research-based assessment, tool essentials, chemicals, and pioneer compounds to help the different drug discovery programs in different academic and industry researchers. In fact, the current conclusive trend-lines from different literature studies explain that not only big pharma giants but also small scale to mid-sized players and academic institutions are benefiting from the ubiquitin enzyme.
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The top Major Competitive Players are 3SBio, 5AM Ventures, Abbiotec, Abcam, AcelRx Pharmaceuticals, Aegera Therapeutics, Aeneas Ventures, Agilis Biotherapeutics, Aileron Therapeutics, Alexion Pharmaceuticals and Amgen among others.
There are various strategic partnerships evolved and had linked various stakeholders to advance research and development processes in ubiquitin enzymes market. Therefore, the growing field of research has gained the attention of various venture capital firms and investors. This factor is expected to foster market growth.
The global ubiquitin enzymes market is segmented on the basis of product type, application, and geography. On the basis of product type, the market is divided into E1 and E2 enzymes as therapeutic targets, E3 enzymes as therapeutic targets, dub enzymes as therapeutic targets and associated drug class. On the basis of application, the ubiquitin enzymes industry is divided into cancer, biological engineering, and others.
Regional segmentation of the ubiquitin enzymes market by Coherent Market Insights comprises North America, Europe, Asia Pacific, Latin America, Middle East, and Africa. North America accounts for the largest share in the global ubiquitin enzymes market owing to the rising number of research centers and the presence of global pharma players.
Key players operating the ubiquitin enzymes market include 3SBio, 5 AM Ventures, Abbiotec, Abcam, AcelRx Pharmaceuticals, Aegera Therapeutics, Aeneas Ventures, Agilis Biotherapeutics, Aileron Therapeutics, Alexion Pharmaceuticals, and Amgen among others. Major market players are constantly working on research and development, as the market is largely untapped and offer highly lucrative growth opportunities. For instance, ubiquitin pathway-based inhibitors, there are over 45 molecules that are under development which are used to treat a variety of indications.
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Key Developments
Rising research and development activities related to ubiquitin enzymes is expected to boost market growth. For instance, in March 2019, researchers from Sungkyunkwan University School of Medicine reported that suppression of the ubiquitin pathway by small-molecule binding to ubiquitin increases doxorubicin sensitivity of the cancer cells.
In November 2018, researchers from Institut national de la recherche agronomique found that Ubiquitin-conjugating enzyme E2 E1 Is preferentially expressed in the cytoplasm of slow-twitch fibers and protects skeletal muscles from exacerbated atrophy upon dexamethasone treatment.
In March 2018, researchers from the Chinese Academy of Tropical Agricultural Sciences found a total of 40 putative ubiquitin-conjugating enzyme genes. The genes were grouped into 15 groups based on phylogenetic analysis.
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