Post-operative pain includes all types of acute pain that occur due to injuries and resolve in an appropriate healing period. Such pain often responds to analgesic medication, as well as a treatment of the precipitating cause. Post-operative pain could also trigger cardiovascular, respiratory, endocrine, metabolic dysfunctions. Post-operative pain treatment is thus aimed at mobilizing the patient as early as possible. It allows the patient to drink and eat and to be able to deep breathe and cough. If the patients are not made to undergo a proper post-operative pain treatment, they can potentially develop cardiac problems, chest infections, depression, wound-induced infection, and hypoxia. Post-operative pain treatment has evolved over recent years, with different concepts of how drugs affect the body when used in specific combinations.
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Opioids and non-steroidal anti-inflammatory drugs are expected to contribute to a major market share, in terms of value, in the global post-operative pain management market. Opioids are substances that act on the opioid receptors to produce morphine-like effects. They are most often used to relieve pain. Whereas, non-steroidal anti-inflammatory drugs are used to treat pain, inflammation, and fever.
Increasing number of surgical procedure is expected to act as a value-driver to the global postoperative pain management market. As per the World Bank, in the U.S. there were 30,537 number of surgical procedures performed in 2012. As per National Center for Health Statistics, of overall surgical procedures half of the procedure requires postoperative pain medication which provides high opportunity for manufacturers. As per Centers for Disease Control and Prevention (CDC), every year there are around 41 million visits in emergency department due to trauma. Around 450,000 burns require medical attention annually. Increase in trauma cases to act as a fuel to the overall growth of postoperative pain management market. Some postoperative pain drugs include side effects. Despite the many advancement in postoperative pain management, opioids are still considered as the mainstay pain therapy in many settings.
All opioids have significant side effects that are limiting its use. One of the major side-effects associated with the use of opioid is respiratory depression. According to CDC, the prescription opioid overdose killed around 16,500 people in 2015. The increasing cases of drug overdoses and side-effects associated with postoperative pain drugs is expected to act as a restraint to the overall market. Increasing geriatric population in emerging economies and increasing prevalent cases of acute diseases is expected to fuel growth of the market. Increasing patient awareness regarding surgeries and operations and the growing research related to pain management is expected to create high opportunity for pain relieving drug manufacturers.
Increasing government’s initiative to promote better postoperative pain treatment is expected to increase growth of market. One such initiative is APOP project (Acute postoperative pain management), it is national multicenter quality improvement initiative started by Australia government in 2008. The project was aimed to improve the management of postoperative pain by promoting the best practice. North America region is expected to contribute major share to the overall postoperative pain management market due to the increasing healthcare expenditure, better reimbursement policies, easy availability of advanced healthcare treatment and growing healthcare infrastructure in these region. Europe is expected to be the second most lucrative market for the postoperative pain management.
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Global Post-operative Pain Management Market – Key Players
The global postoperative pain management market is highly fragmented, owing to the participation of many established and emerging players, such as Bayer AG, DURECT Corporation, Pfizer Inc., BTG International Ltd, Novartis AG, and A.P. Pharma, Inc.
These market contenders are involved in various business strategies, such as gaining product approval from regulatory authorities, in order to strengthen their market presence. For instance, in July 2019, Alembic Pharmaceuticals, a leading India-based pharmaceutical company, received the U.S. Food and Drug Administration (FDA) approval for pregabalin capsules, which are indicated for neuropathic pain. In July 2019, InvaGen Pharmaceuticals, a subsidiary company of Cipla Limited, received the FDA approval for its generic version of pregabalin capsules. These capsules are indicated for the management of neuropathic pain associated with certain diseases. Furthermore, BioElectronics Corporation received the U.S. FDA approval for its RecoveryRX device, which is indicated for treatment of post-operative pain, in August 2019.
Global Post-operative Pain Management Market Taxonomy
On the basis of product type, the global post-operative pain management market is segmented into:
- Non-steroidal anti-inflammatory drugs
- Paracetamol (acetaminophen)
- Ketorolac tromethamine
- Cyclooxygenase-2-selective inhibitors
- Local anesthetics
Based on the type of pain, the global post-operative pain management market is bifurcated into:
- Neuropathic Pain
- Nociceptive Pain
- Visceral Pain
- Somatic Pain
The global post-operative pain management market consists of various distribution channels, including:
- Hospital Pharmacies
- Retail Pharmacies & Drug stores
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