Global Immobilized Trypsin market analysis
Overview
Trypsin (EC number 3.4.21.4) is a serine protease enzyme that hydrolyzes esters of essential amino acids including lysine and arginine in peptides. The ideal temperature for trypsin activation is 37 degrees Celsius, with a pH range of 7.5 to 9.0. As a slurry, immobilized Trypsin is provided with preservatives including glycerol and sodium azide. It is used in science to identify proteins, characterise proteins, review post-translational modifications, and investigate protein-protein interactions.
Many companies produce immobilized trypsin, like Thermo Fischer Scientific, which produces immobilized trypsin Market that has been processed with L-1-TPCK (tosylamido-2-phenylethyl chloromethyl ketone) to suppress chymotrypsin production while maintaining trypsin activity. Promega Corporation, Merck KGaA, and others are among the other suppliers.
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Drivers
In the global immobilized trypsin market, leading manufacturers are producing immobilized trypsin enzyme with a shorter incubation period. Geno Technology Inc. and Promega Corporation’s immobilized trypsin allows a sample to be incubated in the spin columns for 2-18 hours. And at 37 degrees Celsius for 30 minutes, respectively. In the case of Merck KGaA’s trypsin spin columns with immobilized trypsin, the sample must be incubated for 15 minutes at room temperature in the columns. As a result, in the case of Merck KGaA produced substance, the incubation time of the sample with immobilized trypsin has been reduced. This will help researchers by allowing for faster protein digestion for protein analysis.
Immobilized trypsin has several uses in fundamental research. It’s used in affinity chromatography to separate trypsin inhibitors from a solution. Immobilized trypsin has a variety of uses in medicine, including protein-protein interactions and protein recognition in systems biology to locate drug targets in cells. Hence, biomedical studies will benefit from the use of immobilized trypsin since the procedure is cost-effective. Apart from these uses, immobilized trypsin is also used in other areas, such as detecting post-translational changes. Immobilized trypsin also has the advantages of being simple to use, widely available, and having a high specificity. During the forecast period, the aforementioned factors are expected to fuel growth of the global immobilized trypsin market.
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Restraints
Autolysis, intolerance of organic solvents or high temperatures, and losing out on specific locations with post-translational alterations, protein segments, or even subsets of proteins are all drawbacks of using trypsin, as per the NCBI (National Center for Biotechnology Information), 2017. Other enzymes are being investigated for catalytic activity as alternatives to immobilized trypsin in order to address this disadvantage. As per the NCBI (National Center for Biotechnology Information), the catalytic activity of six proteases (AspN, Chemotrypsin, ArgC, LysC, LysN, and GluC) was investigated in 2016, and the proteases were found to have encouraging results. The above factors are expected to restrain the global immobilized trypsin market growth over the forecast period.
Regional Analysis
North America is projected to witness substantial growth in the global immobilized trypsin market during the forecast period, owing to the manufacture of modified immobilized trypsin enzyme with improved throughput and trust in performance. Thermo Fisher Scientific introduced the Thermo Scientific Digest Pack, a protein analysis package for biopharmaceutical applications, in 2015. A thermo-stable immobilized trypsin is included in the package to speed up digestion and ensure high-quality data.
Furthermore, the North American area is home to the headquarters of major manufactures. Promega Corporation, Merck KGaA, and Thermo Fisher Scientific, for example, are all based in the United States. Hence, the above factors are projected to fuel growth of the global immobilized enzymes market during the forecast period.
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Key Players
Major companies contributing in the global immobilized trypsin market include Merck KGaA, Thermo Fisher Scientific, Promega Corporation, and Geno Technology Inc.
Market Segmentation
- According to the Types (Digestion Time),
- Immobilized Trypsin (2 – 18 hrs.)
- Immobilized Trypsin (30 minutes)
- Immobilized Trypsin (15 minutes)
- According to the Application,
- Protein Identification
- Protein Characterization
- Protein: Protein Interactions
- Others
- According to the Region,
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
Main points in Immobilized Trypsin Market Report Table of Content
Chapter 1 Industry Overview
1.1 Definition
1.2 Assumptions
1.3 Research Scope
1.4 Market Analysis by Regions
1.5 Global Immobilized Trypsin Market Size Analysis from 2021 to 2027
11.6 COVID-19 Outbreak: Immobilized Trypsin Industry Impact
Chapter 2 Global Immobilized Trypsin Competition by Types, Applications, and Top Regions and Countries
2.1 Global Immobilized Trypsin (Volume and Value) by Type
2.3 Global Immobilized Trypsin (Volume and Value) by Regions
Chapter 3 Production Market Analysis
3.1 Global Production Market Analysis
3.2 Regional Production Market Analysis
Chapter 4 Global Immobilized Trypsin Sales, Consumption, Export, Import by Regions (2016-2021)
Chapter 5 North America Immobilized Trypsin Market Analysis
Chapter 6 East Asia Immobilized Trypsin Market Analysis
Chapter 7 Europe Immobilized Trypsin Market Analysis
Chapter 8 South Asia Immobilized Trypsin Market Analysis
Chapter 9 Southeast Asia Immobilized Trypsin Market Analysis
Chapter 10 Middle East Immobilized Trypsin Market Analysis
Chapter 11 Africa Immobilized Trypsin Market Analysis
Chapter 12 Oceania Immobilized Trypsin Market Analysis
Chapter 13 South America Immobilized Trypsin Market Analysis
Chapter 14 Company Profiles and Key Figures in Immobilized Trypsin Business
Chapter 15 Global Immobilized Trypsin Market Forecast (2021-2027)
Chapter 16 Conclusions
Research Methodology
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