A chimeric antigen receptor (CAR)-T cell therapy is a type of treatment in which a patient’s T cells, lymphocytes of a type produced or processed by the thymus gland and actively participating in the immune response, are modified to attack cancer cells.
Increasing prevalence of cancer is expected to boost growth of the global CAR-T cell therapy market over the forecast period. For instance, according to the World Health Organization, around 18.1 million new cases and 9.6 million deaths were registered due to cancer worldwide in 2018. Moreover, increasing preference for genetically engineered treatment approaches for the effective treatment of various types of cancers is also expected to aid in growth of the market.
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Increasing investments related to CAR-T cell therapy are expected to fuel growth of the global CAR-T cell therapy market over the forecast period. For instance, in 2016, Novartis International AG invested around US$ 9 billion in R&D in CAR-T cell therapy. Other companies that are actively involved in R&D in CAR-T cell therapy for diffuse large B-cell lymphoma and relapsed/refractory acute lymphoblastic leukemia include Juno Therapeutics and Kite Pharma Inc.
Among regions, North America is expected to hold dominant position in the global CAR-T cell therapy market over the forecast period. This is owing to increasing prevalence of cancer in the region. For instance, according to Fight Colorectal Cancer Organization, there will be an estimated 140,250 new cases of colorectal cancer in 2019 in the U.S.
Europe is expected to follow North America in terms of market share. However, conducting country-specific clinical trials across the region is expected to be a major challenge for growth of the market.
Among the types of therapy, the CD 19-based therapy segment is expected to hold dominant position in the global CAR-T cell therapy market over the forecast period. This is owing to increasing R&D related to CD 19 for the treatment of leukemia. Other antigens such as CD 20 and CD 22 are also expected to witness significant growth.
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Major players in the market are focused on conducting clinical trials to expand their product portfolio. For instance, in February 2020, Precision BioSciences announced its plan to initiate a clinical trial for its new CAR T-cell therapy candidate, PBCAR269A, for the treatment of relapsed or refractory multiple myeloma. The Phase 1/2a trial (NCT04171843) is expected to begin enrolling eligible adults in March at multiple U.S. sites. Moreover, in March 2020, Tessa Therapeutics received the U.S. Food and Drug Administration (FDA)’s Regenerative Medicine Advanced Therapy designation to its investigational CD30-targeted CAR T-cell therapy for the treatment of relapsed or refractory classical Hodgkin’s lymphoma.
Key Takeaways
- Increasing prevalence of cancer to augment growth of the global CAR-T cell therapy market over the forecast period
- North America is expected to account for 58.3% of overall industry share in 2018
- CD 19 segment is expected to touch a billion dollar mark by 2023
- Major players operating in the global CAR-T cell therapy market include, Novartis International AG, Kite Pharma, Inc. (Gilead Sciences, Inc.), Juno Therapeutics (Celgene Corporation), Bluebird Bio, Inc. (Celgene Corporation), Sorrento Therapeutics Inc., Mustang Bio, Inc., Aurora Biopharma Inc., Legend Biotech (Genscript Biotech Corporation), Pfizer, Inc., CARsgen Therapeutics, Ltd., and others.
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Table of Contents
- Research Objective and assumption
- Research Objectives
- Assumptions
- Abbreviations
- Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Market Snippet By Targeted Antigen
- Market Snippet By Therapeutic Application
- Coherent Opportunity Map (COM)
- Report Description
- Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Drivers
- Restraints
- Market Opportunities
- Regulatory Scenario
- Industry Trend
- Epidemiology/Prevalence/Incidence
- Merger and Acquisitions
- New Product Approvals/Launch
- Market Dynamics
- Global Car T Cell Therapy Market, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Introduction
- Market Share Analysis, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, 2017 – 2028
- Segment Trends
- CD 19
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- BCMA
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- HER2
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- GD2
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- CD20
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- CD22
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- CD30
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- CD33
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- HER1
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Others
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Introduction
- Global Car T Cell Therapy Market, By Therapeutic Application, 2017 – 2028 (USD Million)
- Introduction
- Market Share Analysis, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, 2017 – 2028
- Segment Trends
- Acute Lymphocytic Leukemia
- Introduction
- Market Share Analysis, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, 2017 – 2028
- Chronic Lymphocytic Leukemia
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Diffuse Large B-cell Lymphoma (DLBCL)
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Follicular Lymphoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Mantle Cell Lymphoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Multiple Myeloma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Glioblastoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Sarcoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Neuroblastoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Acute Myeloid Leukemia
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Breast Cancer
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Pancreatic Cancer
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Hepatocellular Carcinoma
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Colorectal Cancer
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Others
- Introduction
- Market Size and Forecast, and Y-O-Y Growth, 2017 – 2028, (US$ Million)
- Introduction
- Global Car T Cell Therapy Market, By Regions, 2017 – 2028 (US$ Million)
- Introduction
- Market Share Analysis, By Region, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, For Regions, 2017 – 2028
- North America
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Europe
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Asia Pacific
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Latin America
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Africa
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Middle East
- Market Share Analysis, By Segments, 2017 and 2028 (%)
- Y-O-Y Growth Analysis, By Segments, 2017 – 2028
- Market Size and Forecast, By Targeted Antigen, 2017 – 2028 (US$ Million)
- Market Size and Forecast, By Therapeutic Application, 2017 – 2028 (US$ Million)
- Introduction
- Competitive Landscape
- Heat Map Analysis
- Market Share Analysis
- Company Profiles
- Analyst Views
- Section
- References
- Research Methodology
- About us and Sales Contact
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Major Point Answered in CAR T Cell Therapy Market Research Study are: –
• What will the market growth rate, Overview and Analysis by Type of CAR T Cell Therapy market in 2026?
• What are the key factors driving, Analysis by Applications and Countries CAR T Cell Therapy market?
• What are Dynamics, This Overview Includes Analysis of Scope, and price analysis of top Manufacturers Profiles of CAR T Cell Therapy market?
• Who are Opportunities, Risk and Driving Force of CAR T Cell Therapy market? Knows Upstream Raw Materials Sourcing and Downstream Buyers
• Who are the key vendors in CAR T Cell Therapy market space? Business Overview by Type, Applications, Gross Margin and Market Share
• What are the CAR T Cell Therapy market opportunities and threats faced by the vendors in the market?
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