Alkaline Proteases are a family of polysaccharides and peptides having an important role in various biological processes. Alkaline (alkaline) amino acids are major components of many enzymes and play an important role in energy metabolism, immunity, and the synthesis of DNA and RNA. It plays a crucial role in the development of microorganisms at the level of the genome. Many physiological processes are regulated by these complex polysaccharides.
Bacillus subtilisin is primarily used for the manufacture of alkaline proteases market with biomedical significance. They are important for metabolizing non-energy conserving molecules such as fatty acids, cholesterol, bile salts, and amino acids in blood, skin, muscles, etc. Most of the medically used alkaline proteases found so far are thermo-stabilized with optimal activity levels lying somewhere between 50 C and 70 C. Thermo-stabilized proteins are found in different forms such as peptides (naturally occurring polysaccharides) and complexes (mimetic). Many bacterial sources are also known to contain alkaline proteases. Some of the most common are Shigella (which is a genus of gram-positive bacteria), Enterobacteria, and E coli.
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Expanding protein engineering field along with the development of industrial enzymes is primarily fueling growth of the alkaline protease market. These enzymes demonstrate high stability and resistance to proteolytic hydrolysis, due to their high degree of cross-linking to hydrogen bonds, disulphide bonds, and hydrophobic interactions. Moreover, they are stable in association with chelating agents and perbonates.
By application segment, the alkaline proteases market size has been classified into detergents, pharmaceuticals, meat tenderizers, protein hydrolyzates, food products, and waste processing. Alkaline proteases have important role in the bioprocessing of used X-ray or photographic films for silver recovery. They are widely used in detergents due to their better cleaning properties, safer dirt removal conditions, and higher performance efficiency at lower washing temperature. Immobilized alkaline protease is extracted from Bacillus subtilis has been studied for development of ointment compositions, non-woven tissues, gauze, and new bandage materials. Aspergillus oryzae derived proteases are majorly used as a diagnostic aid in certain lytic enzyme deficiency syndrome. Alkaline proteases with keratinolytic activity are being explored in feather degradation and feather meal production for glues, fertilizers, biodegradable foils, and films.
Bacillus Species: Major Source of Alkaline Proteases
Alkaline protease enzymes can be extracted from bacterial and fungal sources. Other sources include Aspergillus species, Issatchenkia orientalis, Yarrowia lipolytica, Aureobasidium pullulans, and Cryptococcus aureus. Bacillus licheniformis and Bacillus coagulans can be used profitably for large scale production of alkaline protease. Bacillus Species is often commercially used in bioremediation mixes, or as probiotic agent in aquaculture. Alkaline protease from B. subtilis was used for management of waste feathers from poultry slaughterhouse.
Additionally, alkaline proteases extracted from fungal origin provide an advantage of separation owing to easy removal of the mycelia from the final product by simple filtration.
High production cost is inhibiting the widespread use of extracellular enzymes for remediation. Technological development in the field of immobilized enzymes offers possibility of wider and economical use of these enzymes. Advancements in microbiology and biotechnology have created a favorable condition for development of proteases. Extensive studies are underway to increase stability to pH, temperature, organic solvents, reuse, and recovery of enzymes with the help of various enzyme immobilization techniques such as whole cell and cell free immobilization techniques. Characterization of enzymes, isolation and identification of promising strains, and optimization of products is a continuous process for improving existing application and also discovering potential application areas.
Ab Enzymes, Acumedia Manufacturers, Inc., Advanced Enzymes, Novozymes, Noor Enzymes, Royal DSM, Sigma Aldrich Corporation, Solvay Enzymes and Specialty Enzymes & Biotechnologies Co. are some of the key players in the global alkaline proteases market.
Key players in the market are focused on expanding their product portfolio. For instance, in July 2018, Royal DSM introduced PreventASe XR, an enzymatic solution that prevents the formation of acrylamide in high-pH applications to extend use of enzymatic acrylamide-reduction solution to more snacks and baked goods.
Major market players are also focused on expanding their geographical presence to enhance their market share. For instance, in June 2019, Novozymes started a new office in Kenya with the objective to expand its presence in East Africa. Moreover, the company was named the most innovative company in Denmark by European Patents Office in March 2019.
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Table of Content
Global Alkaline Proteases Market Research Report
Section 1: Global Alkaline Proteases Industry Overview
Section 2: Global Economic Impact on Alkaline Proteases Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Alkaline Proteases Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Alkaline Proteases Market Forecast
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