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Mitochondrial Disorders Treatment Market Set to Encounter Paramount Growth with Myriad Advances

September 16th, 2021 Coherent Market Insights Releases

Mitochondrial diseases are the hereditary chronic disorders differentiated by wide variety of genetic and biochemical mitochondrial mutations and defects. This disorder affects various organs, including brain, heart, skeletal muscles, liver, respiratory systems, and kidney. The mitochondrial disorder patients often endure from exercise intolerance, muscle weakness, and fatigue owing to decrease in the mitochondrial respiration, caused owing to mutations of mitochondrial DNA resulting in reduced ability for producing cellular adenosine triphosphate (ATP). In spite of major developments in understanding the molecular mechanisms, presently there aren’t any effective treatments of this disease.

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The mitochondrial disorder treatment is performed mostly with different co-factors, vitamins, off-label drugs licensed for other diseases, along with nutritional supplement. However, pharmaceutical companies and research organizations are focused on development of new drugs with technological advancements such as using biomarkers, sophisticated trial designs, and replacement therapies, thus generating a lucrative growth opportunity in the market.

Rising incidence of mitochondrial diseases causing significant mortality and morbidity combined with higher genetic transmission potentials to next generation are some factors expected to drive growth of the global mitochondrial disorders treatment market over the forecast period. As per the Wellcome Center for Mitochondrial Research, in 2015, over 10 out of 100,000 people had mitochondrial disorders that often express initially in early childhoods. As per the Genetic and Rare Disease Information Center data, women having mitochondrial genetic diseases a have 50% probability with every pregnancy of passing this altered gene along to offspring, therefore indicating increasing burden of this disease.

Moreover, presence of several clinical trials conducted by several research institutes for addressing the unfulfilled requirements of patients having mitochondrial disorders is expected to fuel growth of the global mitochondrial disorders treatment market over the forecast period. For instance, GenSight Biologics, a biopharma company engaged in developing and discovering innovative gene therapies of retinal neurodegenerative conditions and disorders of central nervous system, in April, 2018, declared the results from REVERSE clinical trial in Phase III evaluating the efficacy and safety of one intravitreal GS010 (rAAV2/2-ND4) injection to treat the mitochondrial disease- Leber Hereditary Optic Neuropathy (LHON).

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Higher investments in R&D by organizations to support the researchers to develop efficient therapies for addressing the patients’ unfulfilled medical needs is expected to drive growth of the global mitochondrial disorders treatment market over the forecast period. For instance, the Foundation for Mitochondrial Medicine (FMM) accelerates and supports the development of most potential mitochondrial treatments and research and for treating various mitochondrial disease and disorder types by sponsoring targeted therapeutic discovery project. The FMM, in 2014, in collaboration with Michael J. Fox Foundation for Parkinson’s Research (MJFF) supported the research project from the Department of Neuroscience at Mayo Clinic to investigate a therapeutic approach that is mitochondria-targeted to treat Parkinson’s disease.

Based on geography the global mitochondrial disorders treatment market is segmented into North America, Europe, Latin America, Asia Pacific, Africa, and Middle East. North America is expected to hold a dominant share in the global mitochondrial disorders treatment market during the forecast period, due to rising prevalence of this disease and increasing initiatives for spreading awareness and supporting the development of novel drugs. In 2015, as per the Institute of Medicine, U.S., over 30,000 the U.S. populace was affected by inherited defects within their mitochondria.

Moreover, as per the Foundation for Mitochondrial Medicine, over 1,000 children are born annually with some kind of mitochondrial disorder in the U.S. Furthermore, the North American Mitochondrial Disease Consortium (NAMDC), Rare Disease Clinical Research Network’s (RDCRN) part, works specially towards gathering information from patients of mitochondrial disease into a clinical registry of patients, thereby helping the researchers to recognize and recruit the patients for studies in the future.

Major players functioning in the global mitochondrial disorders treatment market are focused on strategic collaborations along with the research organizations for developing drugs for uncommon diseases by clinical advancements. For instance, NeuroVive Pharmaceutical AB, in February 2018, collaborated with Karolinska Institute to develop a NV556 compound for treating patients having mitochondrial myopathy. This firm is expected to commence clinical trials of this compound with effective outcomes through its preclinical trial.

Reasons to Purchase this Report

Current and future of global Mitochondrial Disorders Treatment market outlook in the developed and emerging markets

The segment that is expected to dominate the market as well as the segment which holds highest CAGR in the forecast period.

Regions/countries that are expected to witness the fastest growth rates during the forecast period

The latest developments, market shares, and strategies that are employed by the major market players

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Major players functioning in the global mitochondrial disorders treatment market are Centogene AG, Ixchel Pharma, GeneDx, Khondrion BV, NeuroVive Pharmaceutical AB, Mitobridge, Reata Pharmaceuticals Inc., Stealth Biotherapeutics, and others.

Global Mitochondrial Disorders Treatment Market: Market Taxonomy

Based on therapy type,

  • Vitamin and Supplement Therapy
  • Dietary Therapy
  • Pipeline Therapies
    • KL1333
    • NV556
    • Others

Based on distribution channel,

  • Hospital Pharmacies
  • Online Pharmacies
  • Retail Pharmacies

Based on geography,

  • North America
  • Europe
  • Latin America
  • Asia Pacific
  • Africa
  • Middle East

About Us:

Coherent Market Insights is a global market intelligence and consulting organization focused on assisting our plethora of clients to achieve transformational growth by helping them make critical business decisions. We are headquartered in India, having an office at global financial capital in the U.S. and sales consultants in the United Kingdom and Japan. Our client base includes players from across various business verticals in over 150 countries worldwide. We pride ourselves in catering to clients across the length and width of the horizon, from Fortune 500 enlisted companies to not-for-profit organizations, and startups looking to establish a foothold in the market. We excel in offering unmatched actionable market intelligence across various industry verticals, including chemicals and materials, healthcare, and food & beverages, consumer goods, packaging, semiconductors, software and services, Telecom, and Automotive. We offer syndicated market intelligence reports, customized research solutions, and consulting services.

Contact:

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