Ascites is a condition distinguished by formation of excess fluid within abdominal cavity, especially within peritoneal cavity. This causes when body is not able to evacuate fluids. When the ascites is caused owing to cancer, it’s known as malignant ascites or malignant peritoneal effusion. Malignancies which are most frequently associated with the malignant ascites are the cancers of liver, ovary, breast, lungs, colon, and lymphoma. In the condition of ascites, lymph glands within the body is blocked, leading to symptoms of ascites including loss of sleep, low blood pressure, fatigue, as well as skin problems. Major symptoms of malignant ascites are abdominal pain or discomfort, shortness of breath, swelling of the abdomen, leg or ankle swelling, weight gain, and constipation.
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Ascites could be diagnosed through ultrasound, CT scans, physical examination, and x-ray test. Survival rate of such patients is extremely low, however, with adequate treatment including paracentesis, surgeries, and chemotherapy are available. Several conventional treatments of malignant ascites are chemotherapy, paracentesis, shunting, and drug use including spironolactone and spironolactone. Cirrhosis of liver is among the common causes of ascites however, other conditions including kidney failure, cancer, heart failure, or infection could also lead to ascites.
Increasing incidence of cirrhosis is the key factor expected to fuel the global malignant ascites market growth over the forecast period. For instance, as per the World Journal of Gastroenterology published study in 2011, around 50% patients have ascites in a decade of diagnosis. As per the Journal of Clinical and Translational Hepatology article published in 2014, stated that advancements in condition of ascites is associated with a poor prognosis, having 15% mortality rate in 1-year and over 44% within 5-year follow up.
Furthermore, favorable policies of reimbursement such as 2010 Patient Protection and Affordable Care Act (PPACA) along with rising incidence of cancer are also propelling the market growth. For instance, according to 2018 American Cancer Society report, cancer was responsible for 609,640 deaths in the U.S. Moreover, major companies are adopting market strategies including acquisitions are expected to propel growth of the global malignant ascites market over the forecast period, For instance, NanoAntibiotics, in 2016, acquired LAT Pharma LLC, a biotechnology startup known for the developments of novel medicines for treating life-threatening liver cirrhosis complications.
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However, complications and stringent regulations related to treatment of ascites including internal bleeding post paracentesis treatment, radiation exposure in chemotherapy is expected to hinder the global malignant ascites market growth over the forecast period. For instance, as per the Experimental & Molecular Medicine published report in 2017, stated that radiation could induce toxicities within non-tumorous tissues of liver tissues which may hamper course of therapy and even have severe chronic side-effects, such as late fibrosis.
Global Malignant Ascites Treatment Market – Regional Insights
Based on region, the global malignant ascites treatment market is segregated into North America, Latin America, Europe, Asia Pacific, Africa, and Middle East. North America holds a dominant position in the global malignant ascites treatment market, due to high expenditure on healthcare, well-developed technologies, and rising incidence of cirrhosis, which is expected to drive the global malignant ascites treatment market within this region. For instance, as per the Journal of Clinical Gastroenterology published study in 2015, showed incidence of cirrhosis within the U.S. was around 0.27%, accounting for 633,323 adults.
Furthermore, Asia Pacific is expected to register robust growth in the global malignant ascites treatment market during the forecast period, due to rising incidence of cirrhosis. For instance, as per the BMJ Open Gastroenterology published study in 2015, hospitalization owing viral hepatitis cirrhosis reduced by 10% from 2006 till 2010, however, alcoholic cirrhosis and non-viral hepatitis cirrhosis exhibited a surge of 33% and 35% in China.
Global Malignant Ascites Treatment Market – Competitive Landscape
Major players functioning in the global malignant ascites treatment market are PharmaCyte Biotech Inc., Fresenius SE & Co. KGaA, Sequana Medical, BD, BioVie, Medtronic plc, GI Supply, Mylan Pharmaceuticals Inc., Actavis Elizabeth LLC, GE Healthcare, Siemens AG, Trion Pharma, and Fresenius Biotech. Key players are focusing on adoption of strategies including collaborations, and rising R&D funding for strengthening the product portfolio as well as retaining their market position, For instance, Lead Compound BIV201 by BioVie received the U.S. FDA Orphan-Drug Designation to treat ascites, in 2016
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Current and future of global Malignant Ascites Treatment market outlook in the developed and emerging markets
The segment that is expected to dominate the market as well as the segment which holds highest CAGR in the forecast period.
Regions/countries that are expected to witness the fastest growth rates during the forecast period
The latest developments, market shares, and strategies that are employed by the major market players
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Global Malignant Ascites Treatment Market – Taxonomy
Based on treatment type,
- Surgical Treatment
- Therapeutic Treatment
Based on application,
- Breast Cancer
- Ovarian Cancer
- Gastrointestinal Cancer
- Carcinoma of Unknown Primary
- Colorectal Cancer
Based on geography
- North America
- Latin America
- Asia Pacific
- Middle East
The study objectives of this report are:
• To study and analyze the global Keyword size (value and volume) by the company, key regions/countries, products and application, history data from 2020 to 2027, and forecast to 2027.
• To understand the structure of Keyword by identifying its various sub-segments.
• To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
• Focuses on the key global Keyword manufacturers, to define, describe and analyze the sales volume, value, market share, market competition landscape, SWOT analysis, and development plans in the next few years.
• To analyze the Keyword with respect to individual growth trends, future prospects, and their contribution to the total market.
• To project the value and volume of Keyword sub-markets, with respect to key regions (along with their respective key countries).
• To analyze competitive developments such as expansions, agreements, new product launches, and acquisitions in the market.
• To strategically profile the key players and comprehensively analyze their growth strategies
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