Genes consists of deoxyribonucleic acid (DNA) that contains vital information to produce proteins that are important for the body’s optimal functioning. Genetic disorders are caused due to gene mutations where proteins are incorrectly made. The gene therapy aims at introducing healthy gene to damaged cells for counteracting abnormal genes or for making a desired protein. Gene therapies are extensively studied globally by researchers to treat various diseases including HIV, Cancer, hemophilia, Parkinson’s disease, and immune deficiencies by several approaches. For instance, as per the Journal Gene Technology and Resistance to Viruses published article in 2015, stated the future prospects of bone marrow gene therapies to treat HIV.
Three major approaches practiced in gene therapy include replacing the mutated gene by healthier one, introducing new gene within body for fighting a disease, and disabling the mutated gene which is functionally inadequate. The treatment of gene therapy that once was considered unfeasible, has currently become the trend in big and small companies. This has resulted in an increase in number of several successful startups, supported by the financiers with leading companies, this in turn is expected to boost growth of the global gene therapy market over the forecast period.
Global Gene Therapy Market – Dynamics
Rising technological developments, pre-clinical and clinical trials, and innovations are expected to fuel growth of the global gene therapy market over the forecast period. Gene therapy demand is increasing significantly owing to rising number of people suffering from cancer, HIV, hereditary disorders, and several chronic diseases. The 2018 report of American Cancer Society, stated that cancer accounted for over 609,640 fatalities within the U.S. Furthermore, the World Health Organization (WHO), in 2017, reported over 1.0 Mn deaths caused owing to illnesses elated to HIV illnesses worldwide. As per the Regenerative Medicine published article in 2014, there were over 4749 registries for stem-cell treatment related clinical trials. Various diseases is expected to propel the global gene therapy market growth during the forecast period. Furthermore, increasing R&D funding from commercial market companies and government agencies to develop innovative, safer, and efficient, practices of gene therapy is expected to propel the global gene therapy market growth during the forecast period. For instance, National Institutes of Health, in 2017 was provided funds worth US$ 1,644 Mn for research of stem cell. Furthermore, rising community acceptance and awareness for gene therapy of several disease treatments is expected to propel the global gene therapy market growth during the forecast period.
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However, undesired immune responses associated with the treatment, concerns regarding gene therapy’s unethical use and high expense of the treatment is expected to restrain the global gene therapy market growth during the forecast period.
Global Gene Therapy Market – Regional Insights
Based on geography, the global gene therapy market is segregated into North America, Latin America, Europe, Asia Pacific, Africa, and Middle East. North America accounts for the highest share in the global gene therapy market, due to well-established facilities of healthcare, extensive R&D activities, high healthcare expenditure per capita, as well as promising policies of medical reimbursement in this region. For instance, the U.S government, in 2018, approved US$ 3 Bn, for research funds of The National Institutes of Health. Moreover, rising incidence of cancer along with several chronic diseases is expected to boost demand for the gene therapies in North America. For instance, as per the report by 2018 American Cancer Society, cancer accounted for 609,640 deaths in the U.S. alone. Moreover, Asia Pacific is expected to register robust growth in the global gene therapy market in the near future, due to increasing population prone to several chronic conditions and availability of novel products providing better solutions for the patients for marginally low costs. For instance, a researchers group headed by the National Cancer Center Japan (NCC), in 2017, along with Toray Industries, Inc. designed a novel method which could detect 13 separate types of cancer with just a single blood drop.
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Global Gene Therapy Market – Competitive Advances
Major players functioning in the global gene therapy market are GlaxoSmithKline plc, Adaptimmune Therapeutics plc, Bluebird Bio, Inc., Celgene Corporation, Merck KGaA, Shanghai Sunway Biotech Co. Ltd., Transgene SA, OncoGenex Pharmaceuticals, Inc., and others. The market players are conducting several pre-clinical and clinical developmental stages for gene therapies. Major players are focused on development of novel technologies and collaborations with leading players for retaining their foothold within the market. For instance, the U.S. Food and Drug Administration (FDA), in 2017, approved the gene therapy named Luxturna, by Philadelphia-based Spark Therapeuticsa Biotech Company.
Based on gene therapy type,
- Somatic Gene Therapy
- Germline Gene Therapy
Based on the type of vector,
- Non-viral Vector
- Viral Vector
Based on disease indication,
- Cardio Vascular Diseases
- Genetic Disorders
- Infectious Diseases
- Neuro Disorders
Based on geography,
- North America
- Latin America
- Asia Pacific
- Middle East
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Table of Content
Global Gene Therapy Market Research Report
Section 1: Global Gene Therapy Industry Overview
Section 2: Global Economic Impact on Gene Therapy Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Gene Therapy Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy, and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Gene Therapy Market Forecast
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