Diclofenac is the nonsteroidal anti-inflammatory drug (NSAID) that works to reduce hormones, which causes pain and inflammation within the body. The non-steroidal anti-inflammatory drug (NSAID) is a widely used therapeutic class in analgesic compounds, prescribed for use to relieve pain of post extraction. The most frequently indicated NSAID is diclofenac sodium which exhibits analgesic, anti-pyretic, and anti-inflammatory activity. Transdermal patches of diclofenac are used for getting temporary relief from minor pains and aches of the joints and muscle that are directly applied to the site of pain. The transdermal patches of diclofenac were more effective, compared to diclofenac tablets, due to the once-daily application along with less systemic adverse effect frequency. Transdermal patches are developed for offering novel drug delivery system of diclofenac, with decreased prevalence of adverse systemic effects owing to lower concentrations of plasma. Diclofenac patch is developed for treating pain related to conditions including gout, migraine, sprain of joints and muscles, rheumatoid arthritis, and moderate to mild fever in certain cases.
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Global Diclofenac Patches Market Drivers
High incidence of the chronic pain disease is expected to drive growth of the global diclofenac patches market over the forecast period. As per the American Academy of Pain Medicine (AAPM), in 2011, over 1.8 bn people were affected by chronic pain. Furthermore, as per the National Institutes of Health (NIH) over 10% the U.S. populace endure with chronic pain. As per the British Medical Journal published study in 2016, over 33% – 50% the U.K. populace are affected by chronic pain. Furthermore, as per the 2015 published, NIH estimates by the American Pain Society (APS), over 50 million populace in the U.S. endured from chronic pain. Furthermore, rising incidence of pain along with increasing incidence of diseases including cancer among others are expected to drive the global diclofenac patches market over the forecast period. For instance, as per the National Cancer Institute, in 2018, over 1,735,350 latest cancer cases are estimated to be detected in the U.S., with 609,640 individuals are estimated to die due to the disease. Moreover, as per the Cancer Atlas: 2017, around 14.1 Mn new cases of cancer were diagnosed in 2012. Furthermore, India, China along with other Central and East Asian nations accounted for over 50% new cases of cancer and deaths, in 2017. Moreover, as per the similar source, till 2025, there would be around 19.3 Mn new cases of cancer and 11.4 Mn deaths by cancer, in emerging economies.
Growing R&D in NSAIDs for increasing its effectiveness for pain management along with extending its applications in several areas of the medical field, which is expected to drive the global diclofenac patches market over the forecast period. For instance, as per the International Journal of Ophthalmology: April 2018, published study, prophylactic non-steroidal anti-inflammatory drugs (NSAIDs) application in post- and pre-cataract surgery might help in reducing the frequency and severity of development of cystoid macular edema (CME) within eyes of the diabetic patients. Moreover, researchers from the Indian Institute of Technology (IIT) Hyderabad, in November 2017, developed a new skin patch that releases diclofenac to the targeted site in such a controlled way that, there would be constant drug release for over 12 hours. Moreover, the drug comes with less half-life of just 1-2 hours, therefore continuous release of up to 12 hrs provides consistent diclofenac efficiency for a prolonged period.
Global Diclofenac Patches Market Restraints
Diclofenac patches possess increased likelihood of heart attacks or strokes if applied for prolonged period than it is prescribed, which is expected to restrain growth of the global diclofenac patches market over the forecast period. NSAIDs result in an increased risk for severe cardiovascular thrombotic events, such as stroke and myocardial infarction (MI), which could be fatal. The risk might occur early during treatment and might increase the usage duration. Diclofenac patches are even associated with more or less side effects such as abnormal pain, vomiting and nausea, skin rash, tinnitus, and constipation.
Moreover, adoption of the diclofenac patch within routine practices are low, than the diclofenac injection or tablet, which is potentially due to absence of awareness as well as mental inertia for accepting new concepts among patients and medical professionals.
Global Diclofenac Patches Market – Regional Analysis
Based on region, the global diclofenac patches market is segregated into North America, Europe, Latin America, Middle East, Africa, and Asia Pacific. North America accounts for the highest share in the global diclofenac patches market, due to high prevalence of sprains, strains of joints and muscle, in the region. As per the National Health Statistics Reports: November 2016, an estimated 4,262 strains and sprains injuries were reported within the U.S. from 2011 to 2014, which also is the key cause of natural injuries (41.4%) in sports as well as recreation-related episodes of injury.
Global Diclofenac Patches Market – Competitive Landscape
Major players functioning in the global diclofenac patches market are Pfizer Inc., GlaxoSmithKline Pharmaceuticals Ltd., Cadila Healthcare, Hisamitsu Pharmaceutical co. Inc., Teikoku Seiyaku Co., Ltd., and others
Global Diclofenac Patches Market Taxonomy
Based on Application
- Sprains
- Lesions
- Strains
Based on End User
- Retail Pharmacy
- Hospital Pharmacy
- Online Pharmacy
Based on Region
- North America
- Europe
- Latin America
- Asia Pacific
- Africa
- Middle East
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