SEATTLE, July 22, 2021, (MEDGADGET) — Global Polymer-drug Conjugates Market Analysis
Polymer-drug conjugates are nanoscale medicinal compounds that are now being utilized to treat cancer and hepatitis. Polymers are being developed that are sensitive to certain enzymes found in sick tissue. Traditional polymers like cellulose and chitin, which are employed in polymer-drug conjugates, can be destroyed by enzyme activity and acidity. The medications remain bound to the polymer and are not active until the sick tissue’s enzymes are present. Healthy tissues are substantially less damaged as a result of this procedure.
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The global polymer-drug conjugates market is projected to expand due to new pipeline medications created via polymer-drug conjugation. The National Cancer Institute (NCI) began a phase II clinical trial for CRLX101, a nanoparticle drug conjugate composed of 20 (S)-Camptothecin covalently linked to a sequential, cyclodextrin-polyethylene glycol-based polymer for the line therapy prostate cancer, in March 2016, and the trial is expected to be completed by March 2020.
The global polymer-drug conjugates market is forecast to expand slowly due to the limited application of polymer-drug conjugates. As per a 2016 report published in Bioengineering and Translational Medicine, polymer-drug conjugates are generated via a covalent bond between the pharmaceutical and the polymer, and not all pharmaceuticals contain chemical functional groups that allow for covalent conjugation. Furthermore, they provide triggered medication release that is limited to tumor tissue or cells.
The lack of defined and improved laboratory or clinical methodologies for evaluating polymer-drug conjugate stability, tumor infiltration, digestion, and toxicity is impeding the global polymer-drug conjugates market expansion.
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Owing to a growth in the number of clinical trials in the U.S., North America is expected to have a dominating position in the global polymer-drug conjugates market. Apellis Pharmaceuticals stated in January 2018 that it will begin a phase III clinical trial for APL-2 in the U.S. APL-2 is a cyclic peptide medication attached to a polyethylene glycol polymer that is used to cure geographic atrophy in age-related macular degeneration.
In addition, rising research on new Drug Delivery Systems (DDS) in Asia Pacific is likely to drive considerable growth in the polymer drug conjugates market in the area over the forecast period. In August 2018, Osaka University developed a DDS employing polyethylene glycol and polylysine block copolymer with ubenimex conjugate (PEG-b-PLys) in conjunction with Tokyo Institute of Technology in Japan (Ube). In mice, intravenous injection of ubenimex with these polymers was found to drastically diminish tumor growth. Such outcomes are projected to provide a beneficial boost to the global polymer-drug conjugates market’s long-term growth.
Major companies contributing in the global polymer-drug conjugates market are GlaxoSmithKline plc., Lipotek, ADAMA India Private Limited, Abeona Therapeutics, Inc., Access Pharma, Gowan Company, Landec Corporation, Avadel, Sansheng Pharmaceutical Group, and JenKem Technology USA.
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Table of Content
Global Polymer-drug Conjugates Market Research Report
Section 1: Global Polymer-drug Conjugates Industry Overview
Section 2: Global Economic Impact on Polymer-drug Conjugates Industry
Section 3: Global Market Competition by Industry Producers
Section 4: Global Productions, Revenue (Value), according to Regions
Section 5: Global Supplies (Production), Consumption, Export, Import, geographically
Section 6: Global Productions, Revenue (Value), Price Trend, Product Type
Section 7: Global Market Analysis, on the basis of Application
Section 8: Polymer-drug Conjugates Market Pricing Analysis
Section 9: Market Chain, Sourcing Strategy and Downstream Buyers
Section 10: Strategies and key policies by Distributors/Suppliers/Traders
Section 11: Key Marketing Strategy Analysis, by Market Vendors
Section 12: Market Effect Factors Analysis
Section 13: Global Polymer-drug Conjugates Market Forecast
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