Acumen Research and Consulting, a global provider of market research studies, has recently published a report titled “Downstream Processing Market (By Product: Chromatography Systems; By Technique: Cell Disruption, Solid-liquid separation, Concentration, Purification by Chromatography, Formulation; By Application: Antibiotic Production, Hormone Production, Vaccines Production, Enzyme Production, Vaccine Production) – Global Industry Analysis, Market Size, Opportunities and Forecast, 2019 – 2026” offers detailed insights of the market entailing insights on its different market segments.
The global Downstream Processing market is expected to reach above US$ 42,754 Mn by 2026 and is expected to register a CAGR of above 13%.
Downstream processing involves recovery of molecules, impurities and contaminants from a complex mixture. The equipments used in downstream processing covers a wide range of system of various size and complexity.
Market Dynamics
An increase in the use of downstream processing strategies for the development of COVID-19 vaccines is a huge factor driving the market. In February 2021, Rentschler Biopharma; Germany-based contract advancement and assembling association (CDMO) reported to begin business production, plan, and downstream preparing of CVnCoV COVID-19 competitor immunization by CureVac. Essentially, Bayer additionally declared to produce 160 million portions of CVnCoV in 2022.
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With continual advancement in quality treatment and genetic engineering methodology towards improvement of new monoclonal antibodies and antibodies is relied upon to additional lift the market development. Slow expansion in number of inpatient in emergency clinics identified with malignancy across the globe, high mortality because of inaccessibility of medications for explicit infections, alongside government interest in biotech innovative work exercises are different factors emphatically sway the market development. The Union Budget in 2017-2018 apportioned Department of Biotechnology US$ 333.31 Mn which is an increment of 22% to keep executing the division’s public biotech methodology and target expanding the turnover from the area to US$ 100 Bn by 2025 from US$ 7 Bn in 2016.
In January 2021, Thermo Fisher Scientific reported that it upheld 250 ventures for COVID-19 treatment just as antibody creation in 2020. The organization uses its CDMO abilities just as its bioprocess consumables and gear contributions for these ventures. It has additionally joined forces with Singapore and the U.S. government to extend its immunization and treatment advancement limits. Comparative endeavors have been made by EMD Millipore, Cytiva, Pall Biotech, and different organizations to utilize their bioprocess contributions for COVID-19 therapeutics advancement.
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Market Segment Analysis
The chromatography systems section ruled the market for downstream handling and represented the biggest income portion of 40.6% in 2020. Ceaseless R&D to improve the proficiency and speed of chromatography systems is expected to drive the portion development. In December 2020, Bolt Biotherapeutics directed chromatography displaying utilizing GoSilico ChromX reproduction programming to speed up bioprocessing.
A rise in the deals and developments relating to chromatography systems likewise works with segment development. For example, in January 2021, Sartorius Stedim Biotech declared to obtain the chromatography gear business from Novasep. This will help Sartorius to foster novel chromatography systems which thus will conquer productivity issues and bottlenecks in downstream handling.
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The channels portion is required to enroll the quickest CAGR from 2021 to 2028. The ascent in the utility of channels for viral inactivation is the key factor driving this market for downstream handling. In September 2020, a group of analysts from Pennsylvania State University investigated the productivity of BioEX empty fiber and Planova 20N infection channels for the expulsion of viral-size particles. Such investigations are expected to build the appropriation pace of channels for downstream handling of biologics.
Segment Analysis by Region
The Asia Pacific downstream processing market is expected to witness faster growth, owing to high government spending on development of biotechnology industry. These are an increase in number of patient suffering from chronic diseases, increasing number of contract manufacturing organizations (CMOs), and various product pipelines related to viral vectors, multi-specific monoclonal antibodies, peptides is expected to further support the market growth in this region. India has the second-highest number of US Food and Drug Administration (USFDA)–approved plants, after the USA and is the largest producer of recombinant Hepatitis B vaccine. Out of the top 10 biotech companies in India (by revenue), seven have expertise in bio-pharmaceuticals and three specialize in agri-biotech.
Competitive Landscape
The players in this field General Electric Company, Thermo Fisher Scientific Inc., Merck KGaA, Sartorius Stedim Biotech S.A., Danaher Corporation, Dover Corporation, Repligen, Boehringer Ingelheim International GmbH, 3M Company, Eppendorf AG, Corning Corporation, Ashai Kasei, Lonza Group Ltd, and Ferner PLC.
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