SEATTLE, July 26, 2021, (MEDGADGET) — Global Bacteriophage Therapy Market – Market Insights
Phages or bacteriophages are referred to bacterial viruses which invades the bacterial cell, disrupting its metabolism and causing lysis in the bacterium. Researches consider bacteriophages as a latest alternative for antibiotics. This therapy includes using viruses to inject into the bacterium its genetic material along with utilizing its host machinery for multiplying themselves. The phage therapy is useful for treatment and prevention of bacterial infections within the patient’s body.
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Global Bacteriophage Therapy Market – Drivers
Rising acquisition and merger activities by players of the market to strengthen their pipeline for candidates of phage therapy along with enhancing their R&D capabilities is expected to drive the global bacteriophage therapy market over the forecast period. For instance, Locus Biosciences Inc., in January 2019, signed a license agreement and exclusively collaborated with Janssen Pharmaceuticals, Inc. (part of the Janssen Pharmaceutical Companies of Johnson & Johnson) for the development, manufacturing, and commercialization of the products for CRISPR-Cas3-enhanced bacteriophage (crPhage) that target two major bacterial pathogens, to treat infection in respiratory tract, along with other linked infections. Janssen Pharmaceuticals, Inc. under the agreement acquired a license for Locus Biosciences Inc. product – CRISPR-Cas3-enhanced bacteriophage product. For this, Locus will accept an initial payment of US$20 million, which is estimated to reach at around US$ 98 million through future sales and commercialization of product.
Moreover, key companies are now collaborating with hospitals and research institutes for conducting clinical trials, in order to evaluate candidates for phage therapy, this is expected to drive the global bacteriophage therapy market growth. For instance, Intralytix, Inc., in May 2019, collaborated with New York Mount Sinai Hospital, to initiate clinical trials of Phase 1/2 for efficacy and safety evaluation of Ecoactive (Bacteriophage preparation) for intestinal adherent invasive e-coli in patients having inactive Crohn’s disease.
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Furthermore, rising incidence of infections caused due to drug resistance is expected to surge the bacteriophage therapy demand in the coming years, which is expected to drive growth of the global bacteriophage therapy market over the forecast period. For instance, in 2015, as per the National Center for Biotechnology Information (NCBI), it was found that the antibiotic resistance pervasiveness in streptococcus pneumoniae was high among Thai children. The multi-drug resistance S. pneumoniae (MDR-SP) was 31.6% prevalent as per the NCBI.
Global Bacteriophage Therapy Market – Regional Analysis
In 2018, North America is expected to gain a dominant share in the global bacteriophage therapy market, owing to acquisitions and partnerships by companies operating in this region. For instance, Adaptive Phage Therapeutics (APT), in December 2018, signed a collaborative agreement with Yale University’s Paul Turner Lab, for supply and manufacturing of therapeutic bacteriophage (phage) used for clinical trials. The agreement under its terms required APT to produce therapeutic phages according to standards of the Food and Drug Administration (FDA, and conditions of Good Manufacturing Practice (GMP). Likewise, a company based in the U.S., ContraFect Corporation, in November 2016, signed a research collaboration with Rockefeller (Rockefeller University) for identifying latest therapeutic candidates for lysin that targets gram-negative bacteria.
Moreover, rising antimicrobial resistance within the population is driving opportunities of growth for manufacturers for expanding their phage therapy products portfolio, which is predicted to initiate a favorable growth environment market in the segment of Asia Pacific. For instance, the Vitalis Phage Therapy, in June 2019, was introduced in India. Eliava Institute of Bacteriophages, Microbiology and Virology at Tbilisi, Georgia developed this programme, for the Indian patients. The programme gave an opportunity to the Indian patients who wished of undergoing phage therapy in Georgia, at Eliava Phage Therapy Center (EPTC)
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Global Bacteriophage Therapy Market – Key Players
Key players functioning in the global bacteriophage therapy market include Armata Pharmaceuticals, Inc., Pherecydes Pharma, Eliava Biopreparations Ltd., Intralytix, Inc., Nextbiotics, InnoPhage, Ltd, Phagelux Inc., Locus Biosciences, Inc., Eligo Bioscience SA, TechnoPhage, Phagomed Biopharma GmbH., Adaptive Phage Therapeutics, Inc., PhagePro, Inc., EnBiotix, Inc., BiomX Ltd., Intodeworld, Inc., Phi Therapeutics, ContraFect Corporation, Fixed-phage Ltd. and Micreos BV.
Table of Contents
- Research Objectives and Assumptions
- Research Objectives
- Assumptions
- Abbreviations
- Market Purview
- Report Description
- Market Definition and Scope
- Executive Summary
- Market Snippet, By Targeted Bacteria
- Market Snippet, By Disease Indication
- Market Snippet, By Route of Administration
- Market Snippet, By Region
- Coherent Opportunity Map (COM)
- Report Description
- Market Dynamics, Regulations, and Trends Analysis
- Antibiotic Resistance – Overview and Epidemiology
- Antibiotics vs. Bacteriophage Therapy – Advantages and Disadvantages
- Drivers
- Restraints
- Opportunities
- Impact Analysis
- Pipeline Analysis
- Regulatory Scenario
- Key Developments
- Merger, Collaboration, Acquisition & Agreements
- PEST Analysis
- Global Bacteriophage Therapy Market – Impact of Coronavirus (COVID-19) Pandemic
- Impact of COVID 19 on Overall Healthcare Market
- Supply Side and Demand Side Analysis
- Key Developments
- Impact on Research and Development
- Global Bacteriophage Therapy Market, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Introduction
- Market Share Analysis, 2020 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Escherichia coli
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Staphylococcus aureus
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Streptococcus
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Pseudomonas aeruginosa
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Salmonella
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Others
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Introduction
- Global Bacteriophage Therapy Market, By Disease Indication, 2016 – 2030, (US$ Mn)
- Introduction
- Market Share Analysis, 2020 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Urinary Tract Infections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Chronic Otitis
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Dental Extraction
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Chronic Ulcerative Colitis
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Bone Infections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Wound and Skin Infections
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Cystic Fibrosis
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Others (eye infections, lung infections, oral infections, GI infections)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Introduction
- Global Bacteriophage Therapy Market, By Route of Administration, 2016 – 2030, (US$ Mn)
- Introduction
- Market Share Analysis, 2020 and 2030 (%)
- Y-o-Y Growth Analysis, 2017 – 2030
- Segment Trends
- Oral
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Topical
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Parenteral
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2016 – 2030, (US$ Mn)
- Introduction
- Global Bacteriophage Therapy Market, By Region, 2016 – 2030, (US$ Mn)
- Introduction
- Market Share Analysis, By Region, 2020 and 2030 (%)
- Y-o-Y Growth Analysis, For Regions, 2017–2030
- North America
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- U.S.
- Canada
- Latin America
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- Brazil
- Mexico
- Argentina
- Rest of Latin America
- Europe
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- Germany
- U.K.
- France
- Italy
- Spain
- Russia
- Rest of Europe
- Asia Pacific
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- GCC
- Israel
- Rest of Middle East
- Africa
- Market Size and Forecast, By Targeted Bacteria, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Disease Indication, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Route of Administration, 2016 – 2030, (US$ Mn)
- Market Size and Forecast, By Country, 2016 – 2030, (US$ Mn)
- South Africa
- Central Africa
- North Africa
- Introduction
- Competitive Landscape
- Competitive Snapshot
- Heat Map Analysis
- Company Profiles
-
-
- Analyst Views
- Section
- References
- Research Methodology
- About us and Sales Contact
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