SEATTLE, June 03, 2021, (MEDGADGET) — Overview:
Oligonucleotides are small DNA or RNA molecules with a particular nucleotide residue sequence that makes up the entire molecule. To form a duplex chain, oligonucleotides bind to their respective DNA-RNA oligonucleotide in a particular sequencing manner. Oligonucleotides are chemically synthesised molecular chains containing phosphoramidite components from natural or chemically modified nucleosides. They have a broad variety of uses in generic testing, science, and forensics.
Covid-19 Impact:
The coronavirus disease (COVID-19) outbreak was first identified in Wuhan, China, on December 31, 2019. COVID-19 was declared a pandemic by the World Health Organization on March 11, 2020.
According to the World Health Organization’s Coronavirus Disease (COVID-19) Weekly Epidemiological Update, over 61.8 million cases and 1.4 million deaths due to coronavirus disease (COVID-19) were registered worldwide up until November 29, 2020.
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Market participants and government agencies are working to investigate the oligonucleotide platform for the advancement of COVID-19 therapy in order to combat the COVID-19 pandemic. For instance, Sarepta Therapeutics, Inc. and the United States Army Medical Research Institute of Infectious Diseases (USAMRIID), the Department of Defense’s lead laboratory for medical biological defence research, signed a cooperative research and development agreement (CRADA) on April 28, 2020 to identify antisense oligonucleotides against SARS-CoV-2 for the treatment of COVID-19.
Drivers:
Increased demand for high quality synthesized oligonucleotides in the market due to Research institutes and diagnostic centers shifting their focus on genomics and genetics is expected to propel the growth of global oligonucleotide synthesis market. For instance, in July 2020, researchers of Rosalind Franklin University of Medicine and Science initiated a new therapeutic approach for treating Batten disease, a fatal neurodegenerative disease in children with the help of antisense oligonucleotides.
Increasing demand for oligonucleotides from pharmaceutical companies due to Biotechnological companies focusing on expanding their manufacturing facilities is expected to boost the growth of global oligonucleotide synthesis market. For instance, in March 2020, STA pharmaceuticals, a subsidiary of WuXi AppTech, announced inauguration of its large scale oligonucleotide active pharmaceutical ingredient manufacturing facility in China
Restraints:
Natural oligonucleotides have a foundation of ribose or deoxyribose sugar phosphate, which is rapidly degraded by the nucleus in the body. Furthermore, oligo-degradation can affect cell growth and proliferation in generic research. Furthermore, the poor quality of microarray-generated oligonucleotide sequences is a significant barrier to microarray-based oligonucleotide synthesis. These factors are expected to hinder the growth of global oligonucleotide synthesis market growth.
The global oligonucleotide synthesis market is estimated to be valued at US$ 2,874.1 Million in 2020 and is expected to exhibit a CAGR of 11.3% during the forecast period (2020-2027).
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Market Taxonomy:
Oligonucleotide Synthesis Market, by Equipment & Services, is segmented into:
- Equipment/Synthesizer
- Reagents
- Services (Oligo Synthesis, Modification, and Purification)
By Technology:
- Column-based
- Microarray-based
By Nucleic Acid:
- DNA
- RNA
By Application:
- Drug Discovery
- Therapeutics
By End User:
- Academic Research Institutes
- Diagnostic Laboratories
- Pharmaceutical-Biotechnology Companies
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
Competitive Section:
Key players involved in the global oligonucleotide synthesis market include Thermo Fisher Scientific, Sigma-Aldrich Corporation, GE Healthcare, Integrated DNA Technologies, Inc., TriLink BioTechnologies, Inc, BioAutomation Corporation, Twist Bioscience, Shanghai SynTheAll Pharmaceutical Co., CUSABIO Technology LLC, Synbio Technologies, GENEWIZ, Eurofins Scientific, Agilent Technologies, Kaneka Eurogentec S.A., and LGC, Biosearch Technologies
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Detailed Segmentation:
- Global Oligonucleotide Synthesis Market, By Equipment & Services:
- Equipment/Synthesizer
- Reagents
- Services
- Oligo Synthesis
- Modification
- Purification
- Global Oligonucleotide Synthesis Market, By Technology:
- Column-based
- Microarray-based
- Global Oligonucleotide Synthesis Market, By Nucleic Acid Type:
- DNA
- RNA
- Global Oligonucleotide Synthesis Market, By Application:
- Drug Discovery
- Therapeutics
- Global Oligonucleotide Synthesis Market, By End User:
- Academic Research Institutes
- Diagnostic Laboratories
- Pharmaceutical-Biotechnology Companies
- Global Oligonucleotide Synthesis Market, By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
- Company Profiles
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