SEATTLE, May 28, 2021, (MEDGADGET) — Heparin is a drug and a naturally occurring glycosaminoglycan that is also known as unfractionated heparin (UFH). Heparin is an anticoagulant that is used to treat a variety of conditions including acute coronary syndrome, atrial fibrillation (AF), venous thromboembolism (VTE), cardiopulmonary bypass for cardiac surgery, and the Extracorporeal Membrane Oxygenation (ECMO) circuit for extracorporeal life support, hemofiltration, and indwelling central or peripheral venous catheters.
Drivers:
High prevalence of AF is expected to boost growth of Europe heparin market over the forecast period. According to the British Heart Foundation’s (BHF) Heart and Circulatory Disease Statistics 2019, released in partnership with the University of Birmingham’s Institute of Applied Health Science, 185,423 men and 155,331 women were diagnosed with AF in England, Scotland, Wales, Northern Ireland, and the United Kingdom in 2017/18.
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Furthermore, R&D to expand the application of heparin is also expected support growth of the market. For instance, Researchers from Chungbuk National University in South Korea announced in June 2020 that heparin-binding peptide may be used to treat rheumatoid arthritis.
Restraints:
Availability of alternative anticoagulants is expected to hamper growth of the market. Warfarin has long been the drug of choice for anticoagulant treatment around the world. Furthermore, new anticoagulants such as rivaroxaban, dabigatran, and apixaban are eating into heparin’s market share.
Furthermore, Heparin use can also cause an increase in serum aminotransferase, hyperkalemia, alopecia, and osteoporosis. As a result of these side effects, the market’s growth is expected to be limited.
Opportunities:
Use of sharp-catching label to prevent needlestick injuries is expected to offer lucrative growth opportunities for players in Europe heparin market. For instance, on medical packaging, B. Braun Medical Inc.’s Heparin Sodium Injection USP prefilled syringes have a needle-securing label created by Schreiner MediPharm.
Furthermore, R&D in heparin mechanism is expected to lead to market expansion. Researchers from Martin Luther University Halle Wittenberg in Germany, for example, published a study in May 2020 that looked at the anti-inflammatory properties of surface coatings made of either hyaluronic acid or heparin in combination with chitosan prepared as multilayers using the layer-by-layer technique.
Europe heparin market was valued at US$ 2,698.7 Mn in 2019 and is forecast to reach a value of US$ 4,085.8 Mn by 2027 at a CAGR of 6.1% between 2020 and 2027.
Europe heparin market is estimated to account for US$ 4,085.8 Mn in terms of value by the end of 2027.
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Regional Analysis:
Germany is expected to witness significant growth in in Europe heparin market during the forecast period. It held a dominant position in 2019 accounting for 28.3% share in terms of volume.
France and UK are also expected to witness significant growth in Europe heparin market during the forecast period.
Market Trends/Key Takeaways:
Major players in the market witnessed significant sales growth. For instance, Laboratorios Farmaceuticos Rovi S A recorded a 42 percent increase in heparin franchise sales (LMWH and other heparins) to around US$ 60 million in the first quarter of 2020.
The effectiveness of heparin alternatives in the treatment of VTE is also being studied by major market players. For example, the Bristol-Myers Squibb-Pfizer alliance revealed in December 2019 that Eliquis use was associated with lower rates of major bleeding, clinically significant non-major bleeding, and recurrent VTE in patients with active cancer as compared to LMWH at American society of hermatology annual meeting.
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Competitive Landscape:
Major players operating in Europe heparin market include., Fresenius SE & Co. KGaA, Leap Labchem Co., LEO Pharma A/S, Sanofi S.A., Syntex S.A., Teva Pharmaceutical Industries Ltd., United Biotech (P) Ltd, Amphastar Pharmaceuticals Inc., Abbott Laboratories, Aspen Pharmacare Holdings, Pfizer, Inc., Sagent Pharmaceuticals, Inc., B. Braun Melsungen AG, Baxter International Inc., GlaxoSmithKline plc, Bayer AG, Anselm Pharmaceuticals, Bristol-Myers Squibb Co., Dr. Reddy’s Laboratories LtdLaboratorios Farmaceuticos ROVI SA, and Intrapharm Laboratories.
Key Developments:
In April 2018, Laboratorios Farmaceúticos Rovi SA signed a license expanding agreement with Hikma Pharmaceuticals PLC for ROVI’s enoxaparin biosimilar.
Market Taxonomy:
Europe Heparin Market, By Product Type is segmented into:
- Low Molecular Weight Heparin
- Unfractionated Heparin
- Ultra Low Molecular Weight Heparin)
By End User:
- Hospitals
- Blood and Stem Cell Bank
- Others (Laboratories, Acute Care Centers)
By Region:
- North America
- Latin America
- Europe
- Asia Pacific
- Middle East
- Africa
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