Summary:
Advanced diagnostics for cancer represent a major market opportunity for life sciences companies. Many cancer types are on the rise as the aging populations of many countries continue to grow. As a result, there is an increasing demand for noninvasive, diagnostic assays that can detect cancers earlier, molecularly subtype tumors to guide therapy decisions and monitor cancer recurrence in treated individuals.
Despite advances in treatment, cancer remains the second leading cause of death, worldwide. Cancer exerts a tremendous toll on patients, families and society as a whole. One pressing need in cancer diagnostics is earlier stage identification, identifying cancer before it has spread to other parts of body. In order to meet this need, a number of companies are using advanced diagnostic platforms to develop and validate assays that detect cancer earlier. Sanomics, Prenetics, Guardant, Thrive Earlier Detection, AnPac BioMedical and Grail are notable examples.
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A second pressing need in cancer is more accurate classification of suspicious lesions or nodules (malignant or benign). Accurate classification leads to better treatment decisions and fewer unnecessary, invasive biopsies. In the case of lung cancer, peripheral lung nodules are very difficult to biopsy, deep within the small branches of the lung, often beyond the reach of the bronchoscope. Needle biopsy is problematic, carrying the risk of lung collapse and/or infection. New, non-invasive blood-based tests are needed to assess nodules.
A third, important medical need is for cancer diagnostics that guide therapy decisions. These diagnostics can be used to assess a patient’s likely response to a particular therapy, providing the physician with a guide to subsequent treatments. This is a growing application for both tissue and liquid-based assays.
These assays establish which of the newer, targeted drugs, including those that block certain molecular pathways, will work most effectively for a given tumor. This convergence of targeted drugs with genomics-based diagnostics leads to a powerful new paradigm in medicine.
Report Scope:
The scope of this report includes next generation diagnostic technologies, applications, industry subsegments, major funding initiatives, patents and companies. The market sizes for next generation cancer diagnostics are given for 2019, 2020 (estimated) and 2025 (forecasted).
This report reviews the main next generation diagnostic technologies, including next generation sequencing (NGS), polymerase chain reaction (PCR), multiplex conventional, cell or extracellular vesicle capture and arrays/microfluidics. The report also discusses, in-depth, various liquid biopsy platforms and how these compare with tissue-based testing.
The report discusses several significant, large-scale research initiatives that contribute to cancer diagnostic development. Key forces driving the market are enumerated.
The structures of several important industry subsectors are reviewed, as well as major industry acquisitions and strategic alliances from Jan. 2019 through June 2020. The industry subsectors analyzed include DNA sequencing instruments, long-read DNA sequencing, informatics, PCR, droplet digital PCR, CTC capture and detection and liquid biopsy.
The market for next generation cancer diagnostics is analyzed in depth. The market is analyzed by cancer site (bladder, brain, breast, colorectal, cancer of unknown primary, gastric, gynecologic, hematologic, kidney, liver, lung, pan-cancer, pancreatic, prostate, melanoma and thyroid), by test purpose (screening/early detection, diagnosis, monitoring, therapy guidance), by test platform (arrays/microfluidics, cell/EV capture, multiplex conventional, PCR and NGS) and by geography (North America, Europe, Asia Pacific, Rest of World).
Market data covers 2019, 2020 (estimated) and 2025 (forecasted).
There is a special section discussing the impact of COVID-19 on the market for next generation cancer diagnostics.
More than 130 companies in the next generation cancer diagnostics industry are profiled in this report.
Report provides a summary of the main industry acquisitions and strategic alliances from Jan. 2019 through June 2020, including key alliance trends.
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Report Includes:
– 22 data tables and 74 additional tables
– An overview of the global market and technologies for next generation cancer diagnostics
– Analyses of global market trends, with data from 2019, estimates for 2020, and projections of compound annual growth rates (CAGRs) through 2025
– Analyses of the next generation cancer diagnostics market by cancer site, analysis purpose, analysis platform and region
– Discussion on arrays and microfluidics (LOAC) technologies, multiplex conventional technologies, next generation sequencing technology and polymerase chain reaction (PCR) technology
– Evaluation of current market trends, market size, market forecast, pipeline analysis of new products, and regulatory scenarios of the cancer diagnostics market
– Discussion on factors affecting the market including cancer diagnostics needs, regulatory trends, industry structure, and patent statuses
– Details of the key initiatives and programs related to the next generation cancer diagnostics market
– Market share analysis of the key companies of the industry, their strategic profiling, competitive landscape, and their detailed company profiles, including Abbott Laboratories, Illumina Inc., Myriad Genetics Inc., Qiagen NV, Oche Holding AG, and Thermo Fisher Scientific Inc.20/20 GENE SYSTEMS
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ABBOTT LABORATORIES
ADAPTIVE BIOTECHNOLOGIES INC.
AGENDIA NV
AGILENT TECHNOLOGIES INC.
AKADEUM LIFE SCIENCES
AMBRY GENETICS
AMOY DIAGNOSTICS CO. LTD.
ANGLE PLC
APOCELL INC.
APOSTLE INC.
Arbor Vita Corp.
ARCHER DX
Arocell Ab
ARUP LABORATORIES
Aspira Labs
ASURAGEN, INC.
Atila Biosystems
AVIVA BIOSCIENCES
BECTON, DICKINSON AND CO.
BGI SHENZHEN
BIO-TECHNE CORP.
BIOCARTIS NV
BIOCEPT INC.
BIODESIX INC.
Biofidelity Ltd.
BIOFLUIDICA INC.
Biolidics Ltd.
BIOLOGICAL DYNAMICS INC.
Bioprognos Sl
BIOTHERANOSTICS INC.
BLUESTAR GENOMICS INC.
CANCER GENETICS INC.
CARIS LIFE SCIENCES
CASTLE BIOSCIENCES INC.
Cc Diagnostics Bv
Celcuity Inc.
CELL MICROSYSTEMS INC.
CELLMAX LIFE
Cellular Analytics
CELSEE DIAGNOSTICS
Chip Diagnostics
CHRONIX BIOMEDICAL
CIRCULOGENE THERANOSTICS
CLINICAL GENOMICS TECHNOLOGIES
CODIAK BIOSCIENCES
DANAHER CORP.
Decipher Biosciences
Dermtech
DIACARTA INC.
DNALYTICS
EPIC SCIENCES INC.
EPIGENOMICS AG
EXACT SCIENCES CORP.
FLUXION BIOSCIENCES INC.
FREENOME INC.
Fulgent Genetics Inc.
Genecentric Therapeutics
GENEDX INC.
Geneoscopy Llc
GENERA BIOSYSTEMS
GENESEQ BIOSCIENCES PTY LTD.
Genetron Health Technologies Inc.
GENEXOSOME TECHNOLOGIES INC.
GRAIL INC.
GUARDANT HEALTH INC.
HOLOGIC INC.
HTG MOLECULAR DIAGNOSTICS INC.
IDL BIOTECH
ILLUMINA INC.
Immunis Ai
Incelldx Inc.
INIVATA LTD.
Interpace Biosciences Inc.
INVITAE INC.
INVIVOSCRIBE INC.
JBS SCIENCE INC.
LABORATORY CORP. OF AMERICA INC.
LEXENT BIO INC.
LUCENCE DIAGNOSTICS PTE. LTD.
LUNGLIFE AI, INC.
MDNA LIFE SCIENCES INC.
MDXHEALTH INC.
Medgenome Inc.
MENARINI SILICON BIOSYSTEMS SPA
Mir Scientific
Miradx
Mutantdx
My Personal Therapeutics Ltd.
MYRIAD GENETICS INC.
Neo New Oncology Gmbh
NEOGENOMICS LABORATORIES
Nodexus
Novigenix Sa
Nrich Dx
Nucleix
NUPROBE INC.
Oncimmune Holdings Plc
ONCOCYTE CORP.
ONCODNA S.A.
OPKO HEALTH
OXFORD GENE TECHNOLOGY
Pacific Edge Ltd.
Pangaea Laboratory
PANGAEA ONCOLOGY
PERSONAL GENOME DIAGNOSTICS INC.
POLYMEDCO, INC.
PREDICINE INC.
PROVISTA DIAGNOSTICS INC.
QIAGEN NV
QUANTUMDX
QUEST DIAGNOSTICS INC.
RARECYTE INC.
RESOLUTION BIOSCIENCE INC.
ROCHE HOLDING AG
Saga Diagnostics Ab
Sanomics Ltd.
Sienna Cancer Diagnostics Ltd.
SINGLERA GENOMICS INC.
SISTEMAS GENOMICOS
Skylinedx Bv
Stage Zero Life Sciences
STRAND LIFE SCIENCES PVT., LTD.
SYSMEX INOSTICS GMBH
THERMO FISHER SCIENTIFIC INC.
Thrive Earlier Detection Corp.
Tiziana Life Sciences Plc
VERACYTE
VOLITIONRX
VORTEX BIOSCIENCES
XING TECHNOLOGIES LLC
YIKON GENOMICS CO. LTD.
Table of Contents
Chapter 1 Introduction
Chapter 2 Summary and Highlights
Chapter 3 Overview
Chapter 4 Technologies
Chapter 5 Liquid Biopsy Technologies
Chapter 6 Next Generation Cancer Diagnostics: Key Initiatives and Programs
Chapter 7 Next Generation Cancer Diagnostic Applications by Cancer Site
Chapter 8 Cancer Diagnostics Industries
Chapter 9 Industry Acquisitions and Strategic Alliances
Chapter 10 Cancer Diagnostics Markets
Chapter 11 Patents
Chapter 12 Company Profiles
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