Cryo-electron microscopy is a technique for imaging solidified hydrated examples at cryogenic temperatures by electron microscopy. Examples stay in their local state without the requirement for colors or fixatives, permitting the investigation of fine cell structures, infections and protein edifices at sub-atomic goal. Cryo-electron microscopy is progressively turning into a standard innovation for considering the design of cells, infections and protein congregations at sub-atomic goal. Late improvements in magnifying lens plan and imaging equipment, matched with upgraded picture handling and robotization capacities, seem ready to additional development the adequacy of Cryo-electron microscopy strategies. These advancements guarantee to speed up and degree of mechanization and to improve the goals that can be accomplished, delivering this innovation fit for deciding a wide assortment of natural structures. Global Cryo-Electron Microscopy Market was valued at just under USD 550 million in 2019 and is expected to reach over USD 1,015 million in 2027, growing at a CAGR of over 1.75% during the forecast period.
By type, global Cryo-Electron Microscopy market is segmented into Electron crystallography, Single particle analysis, Cryo-electron tomography and Others. In 2019, global Cryo-Electron Microscopy market was dominated by electron crystallography segment with almost 40% share in total revenue generation. It is also expected to be one of the fastest growing segments over the forecast period and maintain its dominance. Electron cryomicroscopy, or cryoEM, is an arising strategy for contemplating the three-dimensional structures of proteins and huge macromolecular machines. Electron crystallography is a part of cryoEM in which structures of proteins can be learned at goals that rival those accomplished by X-beam crystallography. Electron crystallography utilizes two-dimensional precious stones of a layer protein inserted inside a lipid bilayer.
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Global Cryo-Electron Microscopy market is segmented on the basis of applications such as Semiconductors, Life Sciences, Material Sciences, Nanotechnology, and Other. Material Sciences segment accounted for the largest revenue share of over USD 150 million in the year 2019. Developing regard for investigation in material science is unsurprising to drive the development of this application fragment. Magnifying instruments are used for the hierarchical and compound assessment of assets, involving metals, pottery, polymers, biomaterials, and alloys.
There is no direct substitute of Cryo-electron microscopy but X-ray crystallography and NMR spectroscopy can be the indirect substitute for it. NMR spectroscopy and X-ray crystallography are also used for determining the atomic structures of macro-biomolecular complexes. Each of them has unique strengths and weaknesses. While the two techniques are highly complementary, they have generally been used separately to address the structure and functions of biomolecular complexes. But recent technical improvements have triggered a resolution revolution in the single particle Cryo-EM method. While X-ray crystallography, NMR spectroscopy and Cryo-EM are different in many respects, from sample preparation to structure determination, they both have the power to solve macromolecular structures at atomic resolution. But, the high price of Cryo electron microscopes (around USD 5 Million Per/Unit) makes it affordable for the big hospitals and research institutions.
Global Cryo-Electron Microscopy market is dominated by North America with over 40% share in 2019. Higher demand for Cryo-Electron Microscopy in the region can be attributed to the presence of large number of research institutes pertaining to Semiconductors, Life Sciences, Material Sciences, and Nanotechnology field. However, Asia Pacific is expected to show tremendous growth over the forecast period.
Major players in global Cryo-Electron Microscopy market include but not limited to FEI, JEOL Ltd., ZEISS International, Hitachi, Ltd., Delong America Inc, Cordouan Technologies and Others. The global Cryo-Electron Microscopy market is highly concentrated with top six players accounting for just over 60% share in the global market.
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Cryo-Electron Microscopy Market by Type, 2015 – 2027 Volume (K Units) and Revenue (USD Million)
• Electron crystallography
• Single particle analysis
• Cryo-electron tomography
Cryo-Electron Microscopy Market by Application, 2015 – 2027 Volume (K Units) and Revenue (USD Million)
Cryo-Electron Microscopy Market by Region, 2015 – 2027 Volume (K Units) and Revenue (USD Million)
• North America
o United States
• Asia Pacific
o South Korea
o Southeast Asia
• Latin America
• Middle East and Africa
o Saudi Arabia
o South Africa
Cryo-Electron Microscopy Market by Company, 2018 – 2019 Volume (K Units) and Revenue (USD Million)
• JEOL Ltd.
• ZEISS International
• Hitachi, Ltd.
• Delong America Inc
• Cordouan Technologies.
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