5-Hydroxytryptophan (5-HTP), also known as oxitriptan, is a precursor to neurotransmitter serotonin and an intermediate product of tryptophan metabolism. 5-HTP is a naturally occurring amino acid that is used to regulate serotonin levels in the central nervous system and brain. 5-HTP is found in low amounts in foods such as cheese and turkey. 5-HTP is sold over-the-counter in Australia, the U.K., U.S. and Canada as dietary supplement that is widely used as antidepressant, appetite suppressant and sleep aid. Global 5-HTP Market was valued at just under USD 54.5 million in 2019 and is expected to reach over USD 93.2 million in 2027, growing at a CAGR of over 8.75% during the forecast period.
By type, global 5-HTP market is segmented into Food Grade and Pharmaceutical Grade. In 2020, global 5-HTP market was dominated by food grade segment with over 50% share in total revenue generation. It is also expected to be one of the fastest growing segments over the forecast period and maintain its dominance.
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Global 5-HTP market is segmented on the basis of applications such as Dietary supplements, Medicine, Food and beverages and Others. Dietary supplements segment dominated the global 5-HTP market with over 50% share in 2020. Retail pharmacy also accounted for significant share in 2020. However, online pharmacy segment is likely to grow at rapid pace over the forecast period. Despite of approval from FDA, 5-HTP has not yet used us main drug for the treatment of cancer. It is more likely used as a combination medication along with other mainstream drugs. Food and beverages is another application that has exhibited remarkable market penetration in a few years. It is poised for further growth. However, growth in food and beverages application is subject to FDA approval of use of 5-HTP as a food supplement.
North America dominated the global 5-HTP market in 2019 with over 45% share in total revenue generated by this industry. North America is closely followed by the Europe. However, with rising healthcare expenditure and growing awareness among people regarding healthcare is likely to drive growth of the 5-HTP market at rapid pace in Asia Pacific. The primary driver of the 5-HTP market is the dietary supplements status it experiences in North America. 5-HTP is generally used for primary insomnia and sleep related diseases; however, scientific studies suggest that 5-HTP hormone is also an effective cancer inhibitor, and is useful to fight depression and anxiety. Since its benefits are amply marketed in North America, over-the-counter sales have surged and the 5-HTP molecule has found reception in the market. Increased stress level among the youth has also contributed to high growth of the 5-HTP market. The same is not true for other markets such as Europe and Asia Pacific, as 5-HTP is largely regulated and is available only with medical prescription.
Major players in global 5-HTP market include but not limited to Linnea SA, Jiaherb Inc., SanHerb Biotech Co. Ltd, Chemill Inc. Xi’an Saiyang Bio-technology Company Ltd. and thers. The global 5-HTP market is highly concentrated with top 5 players accounting for just over 70% share in the global market.
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5-HTP Market by Type, 2015 – 2027 Volume (Tons) and Revenue (USD Million)
• Food Grade
• Pharmaceutical Grade
5-HTP Market by Application, 2015 – 2027 Volume (Tons) and Revenue (USD Million)
• Dietary supplements
• Food and beverages
5-HTP Market by Region, 2015 – 2027 Volume (Tons) and Revenue (USD Million)
• North America
o United States
• Asia Pacific
o South Korea
o Southeast Asia
• Latin America
• Middle East and Africa
o Saudi Arabia
o South Africa
5-HTP Market by Company, 2018 – 2019 Volume (Tons) and Revenue (USD Million)
• Linnea SA
• Jiaherb Inc.
• SanHerb Biotech Co. Ltd
• Chemill Inc.
• Xi’an Saiyang Bio-technology Company Ltd.
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