Gamma Knife – Targeted Brain Tumor Treatment
Gamma knife is a stereotactic radiosurgical device and not an actual knife, which non-invasively treats malignant and benign tumors, vascular malformations, and trigeminal neuralgia in a single patient visit. Cyberknife on the other hand, which can treat cancer anywhere in the body, involves one to five radiation treatment capability. Gamma knife therapy is considered to be much safer than the open-skull surgeries, owing to these factors.
The global gamma knife market is expected to witness steady growth during the forecast period. There are over 300 gamma knife centers worldwide at present, which are estimated to treat nearly 60,000 patients annually. However, there still exists a high demand-supply gap in the countries in pacific region, and Africa continent. China, India, Thailand, South Korea, and Japan are leading countries in terms of the number of gamma knife centers. The global gamma knife market is therefore considerable in this region, however behind North America and Europe where the number of gamma knife centers exists far more than Asia.
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The global gamma knife market was valued at US$ 174.4 million in 2016 and is expected to expand at a CAGR of 7.7% during the forecast period (2017 – 2025).
Market Dynamics
Non-invasive precision to drive the global gamma knife market growth
Growing adoption of non-invasive precision treatment is expected to drive growth of the global gamma knife market during the forecast period. Gamma knife radiotherapy involves convergence of 201 beams that can treat the tumor cell leaving precisely leaving the surrounding healthy cells undamaged. Utilizing the pre-operative diagnostic images form CT/MRI scan, the instrument provides highly accurate irradiation at the tumor site. This is a major factor that drives the usage of gamma knife radiotherapy in treating brain tumors. Application of this procedure is increasing further in trigeminal neuralgia, and arteriovenous malformations.
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However, gamma knife is limited to 190 positions to reach the tumor cells, which in turn, is expected to hinder the global gamma knife market growth up to certain extent.
Alternative treatment options include Cyberknife, LINAC radiosurgery, conventional brain surgery, proton therapy, and modified linear accelerators. Gamma knife is the most researched and established radiosurgery. There are over 2,500 published studies for gamma knife.
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Potential target population for the global gamma knife market
- American Brain Tumor Association:
- Incidence of metastatic brain tumors is estimated in the range of 200,000-300,000 cases annually
- Incidence is high in the age group of 45-64 years
- Approximately 80,000 new cases of primary brain tumors is expected in 2017
- Around 700,000 people in the U.S. living with a primary brain and CNS tumor as of 2016
- American Association of Neurological Surgeons:
- Around 150,000 new cases of trigeminal neuralgia are diagnosed annually in the U.S.
- Disease is more common in women than men
- International Association for the Study of Pain (IASP):
- Global prevalence is in the range of 0.01% to 0.3% (2014)
Considering the current number of patients being treated i.e. 60,000, there exists a major growth potential for gamma knife market. Installation of gamma knife equipment at various locations to improve accessibility would propel the gamma knife market growth in near future.
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