Monocyte activation test is one of the tests or examinations for the detection of pyrogens. A pyrogen is an element or the substance that creates rise in temperature in animal or in human. Pyrogens include heterogeneous class of fever with compounds obtained from microorganisms and the non-microbial elements. This type of pollution is called as a severe public health issue and can lead to symptoms from vascular modifications to death and shock. The MAT testing is essential for ensuring the optimal safety of the parenteral pharmaceutical products as well as the medical devices. The MAT test or the monocyte activation test is capable enough to detect both non-endotoxin and endotoxin pyrogens in one single test. Backed by several regulatory bodies, this strong MAT test assay generates sensitive results depending on the human immune reaction.
Monocyte Activation Test market was valued at over US$ 6.5 Mn. in 2018 and is anticipated to grow at a CAGR of 12.5% from 2019 to 2030.
The global monocyte activation test market is witnessing continuous advancements in test offerings and extensive growth in the product portfolio of major as well as local manufacturers. The growth of the global monocyte activation test market is attributed to increasing number of pharmaceutical and biotechnology industries globally, rising research and development, increased investments and surge in new drug approval activities. Additionally, a proposed ban on animal tests has resulted in reducing the use of the rabbit for pyrogen test. This is one of the significant factors that is driving the growth of monocyte activation tests globally. Increase in public and regulatory concerns about product safety further support the market growth.
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Major Key Players of the Monocyte Activation Test Market are:
Merck, Thermo Fisher Scientific, Becton, Dickinson and Company, Sanquin, Charles River Laboratories International, Inc., Microcoat Biotechnologie GmbH, SOLVIAS AG and Lonza Group among others.
Animals are used to test both the safety and efficacy of therapeutic drugs, cosmetics, household products, and chemicals. Fortunately there are developing numbers of effective non-animal alternatives that can replace the use of animals in pyrogen testing. Moreover, many countries have regulatory requirements that stipulate a ban on animal based pyrogen testing. There have been major changes in the European Union in recent years. In the EU the use of animals for pyrogen testing of cosmetic products has been banned since 2009, the use of animals for the testing of cosmetic ingredients also has been banned since March 2013. Furthermore, the EU banned the sale of any cosmetics tested on animals from March 2013 onwards. Israel imposed similar cosmetic testing bans in 2007 and 2013, and similar policy change is under consideration in India and South Korea. These factors are anticipated to present a lucrative growth opportunity for the global monocyte activation test market in the coming years.
The Monocyte Activation Test Market is segmented on the basis of Product, Source, End Users and region.
Major Product of Monocyte Activation Test Market covered are:
- Monocyte Activation Test Kits
- Reagents
Major Source of Monocyte Activation Test Market covered are:
- Blood Based
- Peripheral Blood Mononuclear Cell (PBMC) Based
- Cell Line Based
Major Applications of Monocyte Activation Test Market covered are:
- Medical Devices
- Lipid Parenteral
- Dialysis Liquids
- Blood Products
- Toxic/immune-modulatory Drugs
Rising prevalence and incidences of several diseases worldwide has triggered the need for advanced R&D scenario across all sectors of biotechnology, pharmaceuticals and research establishments. Both public and private sectors are now focusing on new innovative techniques to obtain latest medical breakthroughs. According to studies, it was estimated that the total spending on R&D by mid-market biotechnology companies, witnessed an increment of approximately 18% between 2015 and 2016. Growing need to address several forms of ailments has been crucial in dictating the funding and R&D spending by government establishments as well as major market players and other research institutes. Increasing R&D investments and spending is anticipated to positively contribute to the growth of the global monocyte activation test market.
Research objectives:-
– To study and analyze the global Monocyte Activation Test consumption (value & volume) by key regions/countries, product type and application, history data.
– To understand the structure of the Monocyte Activation Test market by identifying its various sub-segments.
– Focuses on the key global Monocyte Activation Test manufacturers, to define, describe and analyze the sales volume, value, market share, market competitive landscape, SWOT analysis, and development plans in the next few years.
– To analyze the Monocyte Activation Test with respect to individual growth trends, future prospects, and their contribution to the total market.
– To share detailed information about the key factors influencing the growth of the market (growth potential, opportunities, drivers, industry-specific challenges and risks).
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Table of Contents
- INTRODUCTION
- Market Definition
- Market Ecosystem
- Currency Used
- RESEARCH METHODOLOGY
- Research Framework
- Data Collection Technology
- Data Sources
- Market Estimation Methodology
- Data Validation and Triangulation
- ABSTRACT OF THE STUDY
- MARKET DYNAMICS ASSESMENT
- Overview
- Drivers
- Barriers/Challenges
- Opportunities
- UNIQUE SELLING PROPOSITIONS (USPs)
- Technological Advancement in Pyrogen Tests
- Application Horizon Assessment
- Effectual Turnaround Time for Monocyte Activation Test (MAT)
- Global MAT Market – Analysis & Forecast, By Product
- Monocyte Activation Test Kits
- Reagents
- Global MAT Market – Analysis & Forecast, By Source
- Blood Based
- Peripheral Blood Mononuclear Cell (PBMC) Based
- Cell Line Based
- Global MAT Market – Analysis & Forecast, By Application
- Medical Devices
- Lipid Parenteral
- Dialysis Liquids
- Blood Products
- Toxic/immune-modulatory Drugs
- Global MAT Market – Analysis & Forecast, By End User
- Biotechnology Industry
- Pharmaceuticals Industry
- Medical devices Industry
- Others
- Global MAT Market – Analysis & Forecast, By Region
- North America Monocyte Activation Test Market
- Europe Monocyte Activation Test Market
- Asia Monocyte Activation Test Pacific Market
- Rest of the World (ROW) Monocyte Activation Test Market
- COMPETETIVE LANDSCAPE
- Market Share Analysis (2018)
- Key Strategies Assessment.
- New Product Launches
- Merger & Acquisitions
- Agreements, Collaborations, & Partnerships
- Other Strategies
- COMPANY PROFILES (Business Overview, Products/Services Offered, Financial Performance, R&D Intensity, Marketing & Sales Intensity, Recent Developments, Analyst Corner)*
- Merck KGaA
- Thermo Fisher Scientific
- Becton, Dickinson and Company
- SOLVIAS AG
- Lonza Group
- Charles River Laboratories International, Inc.
- Sanquin
- Microcoat Biotechnologie GmbH (*Finanial details might not be captured in case of privately-held companies or for companies that do not report this information in public domain)
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