Adapalene is a medication, which is used to treat mild to moderate acne. Moreover, adapalene reduces the deposition of the keratin in skin and hence this helps in the effective treatment for keratosis pilaris and callus. Additionally, adapalene suppress the inflammatory response and inhibit lipoxygenase activity and oxidative metabolism of arachidonic acid into prostaglandins, therefore, adapalene is used as an anti-inflammatory agent. Adapalene can be used in combination with benzoyl peroxide as well as with antimicrobial agent such as clindamycin to enhance the maximum efficiency for the treatment.
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Adapalene is available under the brand name of Differin and in different forms such as cream, gel, and lotion. In the U.S., adapalene is available in three different preparation that include 0.1% cream, 0.1% gel, and 0.3% gel, while only 0.1% cream and 0.1% gel are available in Europe. Adapalene is generally used daily once during bedtime and are not applicable to the skin that is sunburned, or broken and until the skin has healed. Adapalene should not be used by the pregnant women, as drug is absorbed through the skin and can be harmful for the unborn baby.
Global Adapalene Products Market Drivers
The global adapalene products market is expected to witness significant growth over the forecast period, owing to increasing approval of adapalene products by the regulatory authorities such as U.S. Food Drug and Administration (FDA). For instance, in 2016, Differin gel 0.1% (Galderma Laboratories company product) was approved by U.S Food Drug and Administration (FDA) for over the counter (OCT) treatment of acne. Differin gel 0.1% is approved for patients who are 12 years and above.
Furthermore, rising prevalence of skin related problems such as acne among populace is another factor that is expected to drive global adapalene products market growth. For instance, according to the National Center for Biotechnology Information(NCBI) 2019 report, out of 100 about 15 to 30 teenagers are suffering from the moderate to severe acne and is mostly found in females, in comparison to male.
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Moreover, availability of less expensive adapalene is the factor that is expected to boost the global adapalene products market growth over the forecast period. For instance, for a 45 g tube, average cost of the prescribed only branded Differin gel 0.1% is US$ 300, while the average cost of the prescribed only generic adapalene 0.1% gel is US$ 150.
Global Adapalene Products Market Restraints
However, side effects associated with the adapalene such as skin discoloration, red skin, contact dermatitis, and intense burning sensation are expected to hamper the global adapalene products market growth over the forecast period.
Moreover, availability of alternative options such as Ziana Gel (Clindamycin Phosphate) is another factor that is expected to hinder the global adapalene products market growth.
Global Adapalene Products Market Regional Analysis
Among regions, North America is expected to account for highest market share in the global adapalene products market over the forecast period, owing to increasing launches of adapalene products such as Epiduo for the topical treatment of acne vulgaris. For instance, in 2017, Teva Pharmaceutical Industries Ltd. launched generic Epiduo gel, which contains 0.1% adapalene and 2.5% benzoyl peroxide. Epiduo gel is used for the treatment of acne vulgaris and is applicable for patients who are of 9 years old or above.
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Moreover, Europe is expected to exhibit highest CAGR over the forecast period due to the increasing launches of adapalene products for the treatment of acne in the region. For instance, in September 2019, La Roche-Posay Laboratoire Pharmaceutique launched Effaclar Adapalene gel 0.1%, which is used in the treatment of acne. From the same source, in 2019, La Roche-Posay Laboratoire Pharmaceutique also launched My Skin Track PoreScan, which is artificial intelligence-based skin app to analyze skin acne, which in turn, is expected to drive demand for adapalene products in the market.
Global Adapalene Products Market: Key Players
Key players operating in the global adapalene products market include Galderma Laboratories LP, Teva Pharmaceutical Industries Ltd., Finorga SA, La Roche-Posay Laboratoire Pharmaceutique, Sandoz, Excella GmbH & Co. KG, Shionogi & Company, Limited, Johnson & Johnson, Stiefel Laboratories, and Niksan Pharmaceutical.
On the basis of formulation, the global adapalene products market is segmented into:
On the basis of application, the global adapalene products market is segmented into:
- Keratosis Pilaris
- Darier Disease
- Actinic Keratosis
On the basis of distribution channel, the global adapalene products market is segmented into:
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
On the basis of region, the global adapalene products market is segmented into:
- North America
- Latin America
- Middle East
- Asia Pacific
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