Pulmonary Arterial Hypertension Market: Global Size, Trends, Competitive, Historical & Forecast Analysis, 2019-2025- Changing consumer lifestyle and growing consumption of alcohol and tobacco drive the market growth.
Global Pulmonary Arterial Hypertension Market is valued at USD 5.85 Billion in 2018 and expected to reach USD 10.36 Billion by 2025 with a CAGR of 8.5% over the forecast period.
Pulmonary arterial hypertension referred to the high blood pressure in the arteries going to the lung. In healthy individuals, the blood pressure in these arteries is much lower than in the rest of the body and the blood pressure of the arteries going to the rest of the body is around 120/80 millimeters of mercury (mm Hg) and pulmonary artery blood pressure is about 25/10 mm Hg. If the pulmonary arterial pressure exceeds about 40/20 mm Hg or the average pressure exceeds 25 mm Hg, then it is called pulmonary arterial hypertension. The right ventricle of the heart, which supplies blood to the pulmonary arteries, is unable to pump effectively If pulmonary hypertension persists or becomes very high. In this situation, the person experiences symptoms such as; loss of energy, shortness of breath and edema, which is a sign of right heart failure. The major cause of pulmonary hypertension is schistosomiasis. The other major risk factor for pulmonary hypertension is high altitude. It is estimated that more than 140 million persons worldwide and up to 1 million in the United States live 10,000 feet or more above sea level. It is more common among women, non-Hispanic blacks, and among people aged 75 or older. Heart failure is common in pulmonary hypertension.
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Global pulmonary arterial hypertension market report is segmented on the basis of drug class and region & country level. Based upon drug class, global pulmonary arterial hypertension market is classified into prostacyclin and prostacyclin analogs, soluble guanylate cyclase stimulators, endothelin receptor antagonists (ERAs) and phosphodiesterase-5 (PDE-5) inhibitors.
The regions covered in this Pulmonary Arterial Hypertension Market report are North America, Europe, Asia-Pacific and Rest of the World. On the basis of country level, the market of Pulmonary Arterial Hypertension is sub divided into U.S., Mexico, Canada, U.K., France, Germany, Italy, China, Japan, India, South East Asia, Middle East Asia (UAE, Saudi Arabia, Egypt) GCC, Africa, etc.
Key Players for Global Pulmonary Arterial Hypertension Market Report–
Some major key players for Global Pulmonary Arterial Hypertension Market are Novartis International AG, Gilead Sciences, Inc., Liquidia Technologies, Inc., Actelion Pharmaceuticals, Ltd., Pfizer Inc., Dong-A ST Co., Ltd., Merck Sharp & Dohme Corp, Reata Pharmaceuticals, Inc., Bayer HealthCare, Toray Industries, Inc., United Therapeutics Corporation, GlaxoSmithKline Plc. (GSK), Arena Pharmaceuticals and others.
Drug Identified that could Reverse Pulmonary Arterial Hypertension.
August 8th, 2018; Scientists at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension (PAH), a severe lung disease with a five-year survival rate of 50 percent. They identified a drug with a positive safety profile that inhibits a gene called HIF-2α, which they discovered earlier promotes the progressive thickening of the lung artery walls—a key feature of PAH called “vascular remodeling,” which leads to right-sided heart failure, the main cause of death in PAH patients. Recently, they demonstrated in three clinically-relevant animal models that inhibiting HIF-2α with a compound results in reversal of established PAH, suppression of vascular remodeling and right heart failure, and increased survival.
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Changing Consumer Lifestyle and Growing Consumption of Alcohol and Tobacco Drive the Market Growth.
The major factor driving the growth of global pulmonary arterial hypertension market is increasing aging population coupled with the increasing prevalence of liver disease (cirrhosis), chronic lung diseases like emphysema and others. For example; As per Statista; According to the data, from 2013 to 2015 there were over 58 thousand alcohol-related cirrhosis deaths and over 61 thousand cirrhosis deaths with other causes. The death rate for alcohol-related cirrhosis was around 5.4 and for all other cirrhosis it was 5.5. The death rate among those aged 45-54 years in 2015 was 13.9 per 100,000. Some other common underlying causes include pulmonary arterial hypertension from some types of congenital heart disease, connective tissue disease, coronary artery disease, high blood pressure, blood clots to the lungs, and chronic lung diseases like emphysema.
In addition, increasing consumption of alcohol and tobacco is also increase the prevalence of pulmonary arterial hypertension and foster the market growth. Furthermore, increasing healthcare spending and favourable government initiatives are also supplementing the market growth. However, lack of awareness may hamper the market growth. In spite of that, increasing approval of new drugs can provide various opportunities for the further growth of the market.
North America is Expected to Dominate the Global Pulmonary Arterial Hypertension Market
The global pulmonary arterial hypertension market is segmented into North America, Europe, Asia-Pacific Latin America and Middle East & Africa. North America is expected to dominate the global pulmonary arterial hypertension market within the forecast period attributed to the highly developed healthcare infrastructure and increasing cases of pulmonary arterial hypertension in this region. In addition, supportive government initiatives and reimbursement policies and presence of leading players are also supplementing the market growth in this region. Asia Pacific is projected to witness a fast growth at a highest CAGR in the global pulmonary arterial hypertension market owing to high population base, improving healthcare infrastructure in this region.
Key Benefits for Global Pulmonary Arterial Hypertension Market Report–
Global Pulmonary Arterial Hypertension Market report covers in-depth historical and forecast analysis.
Global Pulmonary Arterial Hypertension Market research report provides detail information about Market Introduction, Market Summary, Global market Revenue (Revenue USD), Market Drivers, Market Restraints, Market Opportunities, Competitive Analysis, Regional and Country Level.
Global Pulmonary Arterial Hypertension Market report helps to identify opportunities in marketplace.
Global Pulmonary Arterial Hypertension Market report covers extensive analysis of emerging trends and competitive landscape.
Global Pulmonary Arterial Hypertension Market Segmentation: –
By Drug Class:
Prostacyclin and Prostacyclin Analogs
Soluble Guanylate Cyclase Stimulators
Endothelin Receptor Antagonists (ERAs)
Phosphodiesterase-5 (PDE-5) Inhibitors
By Regional & Country Level:
Middle East and Africa
Rest of Middle East and Africa
Table of Content
1. Chapter – Report Causesology
1.1. Research Process
1.2. Primary Research
1.3. Secondary Research
1.4. Market Size Estimates
1.5. Data Triangulation
1.6. Forecast Model
1.7. USP’s of Report
1.8. Report Description
2. Chapter – Global Pulmonary Arterial Hypertension Market Overview: Qualitative Analysis
2.1. Market Introduction
2.2. Executive Summary
2.3. Global Pulmonary Arterial Hypertension Market Classification
2.4. Market Drivers
2.5. Market Restraints
2.6. Market Opportunity
2.7. Pulmonary Arterial Hypertension Market: Trends
2.8. Porter’s Five Forces Analysis
2.8.1. Bargaining Power of Suppliers
2.8.2. Bargaining Power of Consumers
2.8.3. Threat of New Entrants
2.8.4. Threat of Substitute Type and Services
2.8.5. Competitive Rivalry within the Industry
2.9. Market Attractiveness Analysis
2.9.1. Market Attractiveness Analysis by Segmentation
2.9.2. Market Attractiveness Analysis by Region
3. Chapter – Global Pulmonary Arterial Hypertension Market Overview: Quantitative Analysis
4. Chapter – Global Pulmonary Arterial Hypertension Market Analysis: By Drug Class
5. Chapter – Global Pulmonary Arterial Hypertension Market Analysis: By Manufacturer
8. Chapter –Pulmonary Arterial Hypertension Market: Regional Analysis
9. Chapter – Company Profiles
9.1 GlaxoSmithKline Plc.
9.1.3. Type portfolio
9.1.4. Pulmonary Arterial Hypertension Market Revenue (USD Million) and Market Share (%), 2014 – 2018
9.1.5. Pulmonary Arterial Hypertension Sales Market Share (%), 2014 – 2018
9.1.6. Business strategy
9.1.7. Recent developments
9.2. Actelion Pharmaceuticals, Ltd.
9.3. United Therapeutics Corporation
9.4. Pfizer, Inc.
9.5 Gilead Sciences, Inc
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