• Popular
    • Medicine
    • Radiology
    • Cardiology
    • Surgery
    • Nanomedicine
    • Military Medicine
    • Rehab
  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS
  • Submit PR
  • Log in
Medgadget
Medgadget
  • Popular
    • Medicine
      Magnetic Dressing Improves Diabetic Wound Healing

      Magnetic Dressing Improves Diabetic Wound Healing

      Eko’s Newest CORE 500 Stethoscope: A Review

      Eko’s Newest CORE 500 Stethoscope: A Review

      Microfluidic System Incorporates Eight Organ Tissues for Drug Testing

      Microfluidic System Incorporates Eight Organ Tissues for Drug Testing

      Suction Cup Delivers Drugs Through Cheek

      Suction Cup Delivers Drugs Through Cheek

    • Radiology
      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Portable and Radiation-Free Imaging with Magnetic Nanoparticles

      Imaging Technique Reveals Living Brain Tissue in its Complexity

      Imaging Technique Reveals Living Brain Tissue in its Complexity

    • Cardiology
      Eko’s Newest CORE 500 Stethoscope: A Review

      Eko’s Newest CORE 500 Stethoscope: A Review

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      Ultrasound-Equipped Bra Monitors for Breast Cancer

      3D Printed Heart Muscle Beats

      3D Printed Heart Muscle Beats

    • Surgery
      Magnetic Dressing Improves Diabetic Wound Healing

      Magnetic Dressing Improves Diabetic Wound Healing

      Sensor Monitors Transplanted Organs for Signs of Rejection

      Sensor Monitors Transplanted Organs for Signs of Rejection

      Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

      Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

      Droplet Battery Harnesses Ionic Gradients for Bioelectronic Implants

      Droplet Battery Harnesses Ionic Gradients for Bioelectronic Implants

    • Nanomedicine
      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Nanorobots Release Reactive Oxygen Species to Kill Fungal Biofilms

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Bottlebrush Nanoparticles Deliver Immunostimulatory Drugs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Deliver mRNA Therapy to the Lungs

      Nanoparticles Get Lymphatic Vessels Pumping

      Nanoparticles Get Lymphatic Vessels Pumping

    • Military Medicine
      Wearable Can Take Multiple Sweat Samples

      Wearable Can Take Multiple Sweat Samples

      Wound Dressing Detects Infection, Changes Color

      Wound Dressing Detects Infection, Changes Color

      Device Measures Hemoglobin More Accurately in Dark Skin

      Device Measures Hemoglobin More Accurately in Dark Skin

      Fingertip Sensor Measures Lithium Levels in Sweat

      Fingertip Sensor Measures Lithium Levels in Sweat

    • Rehab
      Stretchable E-Skin for Robotic Prostheses

      Stretchable E-Skin for Robotic Prostheses

      Glasses Provide Audible Prompts for Blind Wearers

      Glasses Provide Audible Prompts for Blind Wearers

      A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

      A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

      Robotic Ankle Helps with Postural Control in Amputees

      Robotic Ankle Helps with Postural Control in Amputees

  • Categories
    • Exclusive
    • A-D
      • Anesthesiology
      • Art
      • Cardiac Surgery
      • Cardiology
      • Critical Care
      • Dentistry
      • Dermatology
      • Diagnostics
    • E-I
      • Emergency Medicine
      • ENT
      • Genetics
      • Geriatrics
      • GI
      • Informatics
    • M-N
      • Medicine
      • Military Medicine
      • Nanomedicine
      • Net News
      • Neurology
      • Neurosurgery
      • Nuclear Medicine
    • O-P
      • Ob/Gyn
      • Oncology
      • Ophthalmology
      • Orthopedic Surgery
      • Pathology
      • Pediatrics
      • Plastic Surgery
      • Psychiatry
      • Public Health
    • R-V
      • Radiation Oncology
      • Radiology
      • Rehab
      • Reproductive Medicine
      • Space Medicine
      • Sports Medicine
      • Surgery
      • Thoracic Surgery
      • Urology
      • Vascular Surgery
  • SUBSCRIBE
  • Submit PR
  • About
  • Log in
  • Submit PR
  • Follow
    • Facebook
    • Twitter
    • Linkedin
    • Youtube
    • Instagram
    • RSS

Focused Ultrasound and Microbubbles Push Drugs Across Blood-Brain Barrier

March 5th, 2019 Medgadget Editors Materials, Oncology

The blood-brain barrier is an important defense mechanism that prevents infections and contamination within the brain. It is also responsible for making it extremely difficult to get therapeutic drugs, including chemo agents, into the brain. Now researchers at Washington University in St. Louis have developed an innovative method for pushing drugs across the blood-brain barrier.

The technique, called cavitation dose painting, relies on focused ultrasound to push microbubbles, along with drug molecules, across the barrier without causing much harm. Microbubbles are a contrast agent of ultrasound, and they are extremely sensitive to waves of ultrasound. Microbubbles puff up and back down as ultrasound waves pass through them, creating a localized pumping action. This motion can generate a push in the same direction as the ultrasound waves are heading, which allows it to be used to target the drug to enter the brain in a specific area.

By combining cavitation dose painting with passive cavitation imaging, a technique that can visualize the concentration of microbubbles, the researchers were able to see how much drug ends up actually being transported across the blood brain barrier. To confirm their findings, the team compared the results against positron emission tomography (PET) imaging and showed a “pixel by pixel” correlation between PET and ultrasound imaging in terms of tracking drug particles.

Open access study in Scientific Reports: Cavitation dose painting for focused ultrasound-induced blood-brain barrier disruption…

Via: Washington University in St. Louis…

Medgadget Editors

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

Sponsored
Ark Surgical Performs First Hysterectomies in the USA with its FDA-Cleared LapBox for Manual Morcellation

Ark Surgical Performs First Hysterectomies in the USA with its FDA-Cleared LapBox for Manual Morcellation

PACKAGING COMPLIANCE LABS WELCOMES NEW CFO, BERNADETTE LEGARETTA

PACKAGING COMPLIANCE LABS WELCOMES JENN GOFF, VP SALES, MARKETING, AND INNOVATION

Clarius Debuts its First Dual-Array Wireless Handheld Scanner Enabling Whole-Body Views of Superficial to Deep Anatomy

Clarius Debuts its First Dual-Array Wireless Handheld Scanner Enabling Whole-Body Views of Superficial to Deep Anatomy

National Liver Health Awareness Month Highlights the Urgent Need for Liver Disease Prevention

National Liver Health Awareness Month Highlights the Urgent Need for Liver Disease Prevention

interviews & reviews
A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

A Wearable to Manage Parkinson’s Motor Symptoms: Interview with Lucy Jung, CEO at Charco Neurotech

Eko’s Newest CORE 500 Stethoscope: A Review

Eko’s Newest CORE 500 Stethoscope: A Review

Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

Refillable Device for Drug Delivery Past the Blood-Brain Barrier: Interview with Mike Maglin, CEO at CraniUS

UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

UV-Free Air Decontamination: Interview with Sorel Rothschild, VP at Quantum Innovations

EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

EarliPoint Evaluation System for ASD Diagnosis: Interview with Tom Ressemann, CEO of EarliTec Dx

Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

Visually Guided Uterine Biopsies in Physician’s Office: Interview with Allison London Brown, CEO of LUMINELLE

  • Subscribe
  • Contact us
  • Submit
  • About
  • Back to top
Medgadget

Medical technologies transform the world! Join us and see the progress in real time. At Medgadget, we report the latest technology news, interview leaders in the field, and file dispatches from medical events around the world since 2004.

  • About
  • Editorial policies
  • Contact
  • Terms of Service
  • Privacy
  • Submit press release
  • Advertise
© Medgadget, Inc. All rights reserved. | The Medical Revolution Will Be Blogged.
Please support this website by adding us to your whitelist in your ad blocker. Ads are what helps us bring you premium content! Thank you!