A team of researchers from Howard Hughes Medical Institute, Harvard, Stony Brook, Caltech, and UC Berkeley have developed a remarkable new microscope for looking at living cells in 3D still inside the body. The microscope relies on a technique dubbed as lattice light-sheet microscopy, which involves passing a plane of light through tissue repeatedly. The beam of light is powerful enough to image the insides of individual cells, but because it’s focused into a very narrow sheet it doesn’t seem to disturb the processes taking place inside the cells.
Here are a video of a bunch of amazing imagery captured using the new microscope:
Image credit: T. Liu et al./Science 2018
Study in journal Science: Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms…