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Table of Contents
1. An Introductory Insight into Photodynamic Cancer Therapy
1.1 Overview
1.2 History and Evolution of the Photodynamic Cancer Therapy
2. Photodynamic Therapy andndash; A Breakthrough in Modern Cancer Therapy
2.1 Dire Need for Photodynamic Therapy in Cancer Treatment andndash; An Insight into its promising features
2.2 Superiority of Photodynamic Cancer Therapy over Traditional Cancer Therapy Method
3. Working Mechanism of the Photodynamic Cancer Therapy- It’s Components and Their Role
3.1 Procedure for Photodynamic Therapy
3.2 Photosensitizers (PS) andndash; A Crucial Component of the Photodynamic Therapy
3.2.1 Classification of Photosensitizers
3.2.2 Desired Features of an Effective Photosensitizer Agent
3.2.3 Photosensitizers Currently Used in Photodynamic Therapy
3.3 Oxygen – The Vital Substrate in Photodynamic Therapy
3.4 Light Source – For Safe and Effective Activation of the Photosensitizer
4. Photosensitizer Delivery andndash; For Increased Efficacy of the Photdynamic Therapy
4.1 Organic Nano Particles Photosensitizer Delivery in Photo Dynamic therapy
4.2 Inorganic Nanocarrier of Photosensitizers in Photodynamic Therapy
5. Anti-Tumor Activity of the Photodynamic Therapy
5.1 Direct Tumor Photodynamic Therapy Damage
5.2 Vascular Damage
5.3 Inflammatory and Immune Response
6. Current Status of Various Cancer Treatments Using Photodynamic Therapy
6.1 Non-Melanoma Skin Cancer
6.2 Prostate Cancer
6.3 Breast Cancer
6.4 Brain Tumor
6.5 Lung Cancer
6.6 Head and Neck Cancer
6.7 Oral Lesions and Oesophageal Cancer
6.8 Cervical Cancer
6.9 Colorectal Cancer
6.10 Cancer of the Bile Duct and the Pancreas
7. Photodynamic Combinational Cancer Therapy- Overcoming Current Cancer Therapy Limitations
8. Recent and Promising Advances in the Photodynamic Therapy Segment
8.1 Intracellular “Activated” Two-Photon photodynamic Therapy for Breast Cancer
8.2 Gold Nano-Clusters: A New Nanotech Innovation for Photodynamic Therapy.
8.3 Photodynamic Therapy and Combinational Therapy using Microbial Adjuvants and Cytokines
9. Current Market Scenario of the Photodynamic Therapy and its Cognizance in the Oncology Segment
9.1 Global Photodynamic Therapy Market Analysis by Device and Essentials
9.2 Regional Analysis of the Photodynamic Therapy Market
9.2.1 North America
9.2.2 Europe
9.2.3 Asia Pacific
9.2.4 Latin America, Middle East and Africa
10. Favorable Factors for the Growth of Photodynamic Cancer Therapy Market
10.1 Rise in Global Cancer Incident
10.2 Increasing Awareness Regarding Photodynamic Therapy
10.3 Limitations and Failures of Existing Cancer Therapeutics
10.4 Advancement in Research and Development
10.5 Increasing Investment in the Photodynamic Therapy Segment
10.6 Presence of a Strong Clinical Pipeline
10.7 Approvals of the FDA
11. Challenges to the Photodynamic Therapy Market Growth
11.1 Technical and Scientific Limitations
11.2 Dominance of Conventional Therapeutics
11.3 Commercial Challenges
11.4 Patient Specific Issues
11.5 Side Effects Associated with the Photodynamic Therapy
12. Anticipation Regarding the Future of Photodynamic Cancer Therapy
13. Global Cancer Photosensitisers Clinical Pipeline by Company and Phase
13.1 Preclinical
13.2 Phase-I
13.3 Phase-I/II
13.4 Phase-II
13.5 Phase-III
13.6 Registered
14. Marketed Cancer Photosensitisers Clinical Pipeline by Company
14.1 Hexyl Aminolevulinate (Cevira, Cysview, Hexvix and Hexvix PDT)
14.2 Methyl Aminolevulinate (Metvix, Metvix PDT, Metvixia and Visonac)
14.3 Talaporfin (Aptocine, Aptocine, Aptocine and Litx)
14.4 Aminolevulinic Acid (Litx and Alaglio)
14.5 Aminolevulinic Acid (Alaglio, Effala, Gleolan and Gliolan)
14.6 Porfimer Sodium (Photobarr, Photofrin, Photofrin II and Photofrin PDT)
14.7 Methoxsalen Solution (UVADEX)
14.8 Temoporfin (Foscan)
15. Competitive Landscape
15.1 Theralase Technologies
15.2 Dusa Pharmaceuticals
15.3 Biofrontera AG
15.4 Soligenix
15.5 Coherent
15.6 Lumenis
15.7 Nanoprobes
15.8 PhotoMedex
15.9 Biolitec
15.10 Ambicare Health
15.11 Quest Pharma Tech
15.12 Photolitec
Figure 1-1: Evolution of Photodynamic Therapy
Figure 2-1: The Need for Cancer Photodynamic Therapy
Figure 2-2: Superiority of Cancer Photodynamic Therapy over Other Methods
Figure 3-1: Working Principle of Photodynamic Therapy
Figure 3-2: Desired Features of an Ideal Photosensitizer
Figure 3-3: Cellular Mechanism of Photodynamic Therapy
Figure 3-4: Various Types of Light Sources Used in Photodynamic Therapy
Figure 4-1: Drug Carriers for Photodynamic Therapy
Figure 4-2: Delivery of Photosensitizer Drugs Using Liposomes
Figure 4-3: Structure of a Quantum Dot
Figure 4-4: Gold Nanoparticles for Targeted Delivery of Photosensitizers
Figure 5-1: Apoptosis of Tumor Cell Induced by Photodynamic Therapy
Figure 5-2: Vascular Damage of Tumor Cells Induced By Photodynamic Cancer Therapy
Figure 5-3: Tumor Cell Death Pathways by Reactive Oxygen Species
Figure 6-1: Photodynamic Therapy for Lung Cancer
Figure 6-2: Photodynamic Therapy for the treatment of Cervical Cancer
Figure 7-1: Limitation of Cancer Photodynamic Therapy
Figure 9-1: Use of Photodynamic Therapy for Various Skin Cancer Types
Figure 9-2: Global andndash; Cancer Photodynamic Therapy Market Opportunity (US$ Billion), 2017-2023
Figure 9-3: Global – Cancer Photodynamic Therapy Shares by Devices and Essentials
Figure 9-4: Global andndash; Cancer Photosensitisers Clinical Pipeline by Phase (%), 2017 till 2023
Figure 9-5: Global – Photosensitisers Clinical Pipeline by Phase (Number), 2017 till 2023
Figure 9-6: Global andndash; Cancer Photosensitisers Clinical Pipeline by Phase (%), 2017 till 2023
Figure 9-7: Global andndash; Cancer Photosensitisers Clinical Pipeline by Phase (Number), 2017 till 2023
Figure 10-1: Global – Driving Factors of the Cancer Photodynamic Therapy Market
Figure 10-2: Global – Breast, Lung and Skin Cancer Statistics, 2013-2016
Figure 11-1: Global andndash; Cancer Photodynamic Therapy Market Challenges
Figure 11-2: Global – Scientific Limitations of the Cancer Photodynamic therapy
Figure 11-3: Global – Commercial Challenges to the Photodynamic Therapy Market
Figure 12-1: Global – Future Governing Factors of the Photodynamic Therapy Market
