In-vitro toxicology testing is the scientific analysis of toxic effects produced by chemical substances on cultured mammalian cells or bacteria. Toxicity testing is very essential in drug discovery as identifies the toxic effects of new compound in the early stages of drug discovery. This early detection of toxicity reduces the development cost and time.
North America in-vitro toxicology testing market is expected to reach USD 7.89 billion by 2021 from USD 4.19 billion in 2016, growing at a CAGR of 13.50% for the next five years 2016-2021.
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Favorable regulatory authorities for toxicology testing using the in-vitro tests, growing technological advancements in toxicity testing models, increasing research & development expenditure towards cell culture, existence of stringent regulations related to animal utilization for toxicity testing, and increasing demand for in-vitro tests are driving the growth of in-vitro toxicology testing market in North America. However, requirement of extensive validation procedures for new in-vitro method and presence of stringent social & scientific laws pertaining to toxicology testing studies are some of the factors that restrain the growth of in-vitro toxicology testing market in North America.
North America in-vitro toxicology testing market is segmented based on the product, type, toxicity endpoints & tests, technology, method, and industry. Based on product, the market is further sub-segmented as assays, reagent & labware, and service. Assays segment is estimated to command the largest share of North America in-vitro toxicology testing market by product in 2016. Based on type, the market is segmented as ADME, dose, and toxic substance.
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Toxicity endpoints & tests is further segmented as systemic toxicity, dermal toxicity, carcinogenicity, ocular toxicity, skin sensitization & irritation, genotoxicity, neurotoxicity, and organ toxicity. Systemic toxicity is estimated to command the largest share of North America in-vitro toxicology testing market by toxicity endpoints & tests in 2016. Technology is further segmented as OMICS technologies & cell culture technology.
By method, the market is segmented as in-silico method, biochemical assays, cellular assays, and ex vivo models. In-silico method is estimated to command the largest share of North America in-vitro toxicology testing market by method in 2016. The market, by industry, is sub-segmented as cosmetics & household products, pharmaceutical, diagnostics, chemical, & food. The cosmetics & household products industry is estimated to account for the largest market share of North America in-vitro toxicology testing market by industry in 2016.
On the basis of geographical areas, North America in-vitro toxicology testing market is segmented as U.S., and Canada. U.S., is estimated to account for larger share of the North America in-vitro toxicology testing market in 2016, whereas Canada is estimated to grow at a higher CAGR during the forecast period 2016-2021.
The key players in in-vitro toxicology testing market include, Covance, Inc. (A subsidiary of LabCorp) (U.S.), Agilent Technologies, Inc. (U.S.), Bio-Rad Laboratories, Inc. (U.S.), Eurofins Scientific SE (Luxembourg), General Electric Company (U.S.), BioReliance, Inc. (A subsidiary of Merck & Co, Inc.) (U.S.), Charles River Laboratories International, Inc. (U.S.), Thermo Fisher Scientific, Inc. (U.S.), Catalent (U.S.), and Cyprotex (U.K.), among others.
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